DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FarO and far1

DIOPT Version :9

Sequence 1:	NP_652021.1	Gene:	FarO / 45707	FlyBaseID:	FBgn0023550	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	XP_005174372.1	Gene:	far1 / 406829	ZFINID:	ZDB-GENE-040426-2908	Length:	518	Species:	Danio rerio

Alignment Length:	515	Identity:	150/515 - (29%)
Similarity:	255/515 - (49%)	Gaps:	57/515 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 EFFEDSEIFVTGGSGVVGKALVEKLLRSC-NVRRIYVLLRPRKQLTAEQRLVRLRQATVFHVLAV 74
            |::....:.:||.:|.:||.|:||||||| .|:..|||:||:.....:.|:..:....:|..|..
Zfish     6 EYYVGKNVLITGATGFMGKVLLEKLLRSCPGVKAAYVLVRPKAGQAPDARIADMINCKLFDRLRE 70

  Fly    75 QKPEELDKIVAVPGDVSLPGLGIDPSMMQRMKG-VSLVYHCAATVRFDEPLREAVRLNVGGTLEA 138
            .:|:...||||:..|::.|.|.:.....:.:.| :::|:|||||:||:|||::|::|||..|.:.
Zfish    71 DQPDFAGKIVAINSDLTQPNLDLSAEDQETLTGCINVVFHCAATIRFNEPLKDAMQLNVLATQKM 135

  Fly   139 LKFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSSPMDWRLCLRMIDDV--ADDGMLNALTRKLI 201
            :..|..:..|..||||||.|:|.....:|...|..|:|:|   ::||.:  .||.:::.:|.:|:
Zfish   136 VSLAHRMKHLEVFIHVSTAYANCDRELIEEVVYPPPVDYR---KLIDTLEWMDDKLVSLMTPRLL 197

  Fly   202 MGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALVGAGIL 266
            ...|||||:||.|||.||......|.:.:.|||||..:.::|.||:..:..|..|:|...|.|||
Zfish   198 GERPNTYTYTKALAEQLVQQECGNLNIAIIRPSIVGASWKEPFPGWIDNFNGPSGIFIAAGKGIL 262

  Fly   267 KTVYLGKDIRLDITPQDIGIKSMLC---YTKMGYDIYRQGPPADLPVFLSSSCT----------- 317
            :|:....:...|:.|.|:.|.:.|.   |:    ...|...|..|.|:   :||
Zfish   263 RTMRASNNAVADLVPVDVVINTTLAAAWYS----GSQRHARPRSLLVY---NCTTGGINPFHWGE 320

  Fly   318 ---HVPHTFTQ-IAEQMDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALILDLLL 378
               ||..||.: ..||          ||.:    |..:.|......|:.:......||.:.||.|
Zfish   321 VEYHVISTFKRNPLEQ----------AFRR----PNVNLTTNHLINQYWIAVSHKAPAFLYDLFL 371

  Fly   379 RIFGQKPVLMSAVRKAYQTLEVMQPFMFNN--WDSPGVSDMETLSKHGEGSAFNFDAFNHPDIHG 441
            |:.|::|.:|..:.:.::.:.|::.|..::  |::..|:.:.......:...||||.   ..:|.
Zfish   372 RMSGREPRMMKTITRLHKAMMVLEYFTSHSWVWNTDNVTMLMNQMGAEDKKVFNFDV---RQLHW 433

  Fly   442 LVIQSCSNMLHSIRTHLLREDPKTLERSKRILRIKVFLYRLLRLFLLYKLILWLWRSYLA 501
              .:...|.....:.::|.|:...|..:::.|.    ..|.:|......|::.:||.::|
Zfish   434 --AEYMENYCMGTKKYVLNEELSGLPAARKHLN----KLRNIRYTFNTVLVVLIWRIFIA 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FarO	NP_652021.1	FAR-N_SDR_e	18..328	CDD:187547	113/331 (34%)
FarO	NP_652021.1	FAR_C	379..>410	CDD:296071	6/32 (19%)
far1	XP_005174372.1	FAR-N_SDR_e	11..333	CDD:187547	113/331 (34%)
far1	XP_005174372.1	Sterile	360..450	CDD:308580	19/94 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593270
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	1	1.100	-	-	O	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.850