DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FarO and CG5065

DIOPT Version :9

Sequence 1:	NP_652021.1	Gene:	FarO / 45707	FlyBaseID:	FBgn0023550	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001163168.1	Gene:	CG5065 / 36860	FlyBaseID:	FBgn0034145	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	164/529 - (31%)
Similarity:	258/529 - (48%)	Gaps:	76/529 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 EFFEDSEIFVTGGSGVVGKALVEKLLRSC-NVRRIYVLLRPRKQLTAEQRLVRLRQATVFHVLAV 74
            :|:....:|:|||:|.:||.||||||||| .:|.||:|:||::......||..|..|.:|..|..
  Fly   121 QFYAGRSVFITGGTGFMGKVLVEKLLRSCPEIRNIYLLIRPKRGQEVSARLTELLNAPLFESLRQ 185

  Fly    75 QKPEELDKIVAVPGDVSLPGLGI---DPSMMQRMKGVSLVYHCAATVRFDEPLREAVRLNVGGTL 136
            :||:||.|::.:.||::...|||   |.:::.|  .||:|:|.||||:|||.|:.:|.:|:.||.
  Fly   186 EKPKELSKVIPISGDITSEELGISEKDQNLLCR--NVSVVFHSAATVKFDEKLKLSVTINMLGTK 248

  Fly   137 EALKFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSSPMDWRLCLRMIDDVADDGMLNALTRKLI 201
            ..::....:..|.|.|||||.|.|...|.|....|:.|.:....:.:|:.:.:| :|:.||.:||
  Fly   249 RLVELCHRMLSLDALIHVSTAYCNCDRTDVSEVIYAPPYNPDDIISLINWLPED-ILDQLTPRLI 312

  Fly   202 MGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALVGAGIL 266
            ...||||||||.|||.::......|||.:.|||||..::.:|..|:..:..|..||.:.:..|:.
  Fly   313 GKRPNTYTFTKALAEHMLLKEAGNLPVAIVRPSIVTASLNEPFAGWVDNFNGPTGLVSALAKGMF 377

  Fly   267 KTVYLGKDIRLDITPQDIGIKSMLCYTKMGYDIYRQGPPADLPVFLSSSCT----------HVPH 321
            :|:...|:...|:.|.||.|..|:...      :|........:.:.:.||          .|.|
  Fly   378 RTMMCEKNYVADMVPVDIVINLMIAAA------WRTATRKSNNLLIYNCCTGQRNPIIWSEFVKH 436

  Fly   322 TFTQIAEQMDTLDLW---RDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALILDLLLRIFGQ 383
            ..|.:.:......||   .|:...:.:....|             ..|..|||.|||.:.||.|:
  Fly   437 AMTSVRKHPLEGCLWYPTGDLRMNRPMNTLNC-------------IAKHFLPAYILDGVARIMGK 488

  Fly   384 KPVLMSAVRKAYQTLEVMQPFMFNNW---DSPGVSDMETLS-KHGEGSAF-----NFDAFNHPDI 439
            ||.:::...|..:.:|.::.|....|   |....:.:.||| |..|...|     |:|.:....:
  Fly   489 KPFVVNVQNKIAKAVECLEYFATRQWRFKDDNVHALLHTLSPKDREIFVFDVRHINWDKYVERYV 553

  Fly   440 HGLVIQSCSNMLHSIRTHLLREDPKTLERS-KRILRIKVFLYRLLRLFLLYKLILW--------- 494
            .|            .|..|.::.|::|..| ||:||: .:|::|.:|..:  |:.|
  Fly   554 LG------------FREFLFKQRPESLPASRKRMLRL-YYLHQLTKLVAV--LLTWRFLMSRSKR 603

  Fly   495 ---LWRSYL 500
               ||.|:|
  Fly   604 LNDLWSSFL 612

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FarO	NP_652021.1	FAR-N_SDR_e	18..328	CDD:187547	115/323 (36%)
FarO	NP_652021.1	FAR_C	379..>410	CDD:296071	9/33 (27%)
CG5065	NP_001163168.1	FAR-N_SDR_e	126..445	CDD:187547	115/327 (35%)
CG5065	NP_001163168.1	Sterile	472..562	CDD:281068	27/101 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466818
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	10	9.750