DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FarO and CG8303

DIOPT Version :9

Sequence 1:	NP_652021.1	Gene:	FarO / 45707	FlyBaseID:	FBgn0023550	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001286495.1	Gene:	CG8303 / 36858	FlyBaseID:	FBgn0034143	Length:	543	Species:	Drosophila melanogaster

Alignment Length:	564	Identity:	155/564 - (27%)
Similarity:	245/564 - (43%)	Gaps:	122/564 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HPLSGEM--EEFFEDSEIFVTGGSGVVGKALVEKLLRS-CNVRRIYVLLRPRKQLTAEQRLVRLR 64
            |.||..:  .|||....||||||:|.:|..|:|.||.: .::..||||:|.:::....:|:.||.
  Fly    31 HQLSTSLTIPEFFAHKNIFVTGGTGFLGTVLIEALLDTHPDIGTIYVLVRGKRKFDPNERIRRLL 95

  Fly    65 QATVFHVLAVQKPEE--LDKIVAVPGDVSLPGLGIDPSMMQRM-KGVSLVYHCAATVRFDEPLRE 126
            |..:|     :|..|  |.|:|.|.|::|.|..|..|.::|.: ..|:::||.|||::|..|||.
  Fly    96 QKPIF-----EKYSEKTLSKVVPVVGELSEPNFGFGPELLQELIDRVNVIYHSAATIKFSSPLRT 155

  Fly   127 AVRLNVGGTLEALKFAETLPQLRAFIHVSTFYSNPYLTR--VEPKYYSSPMDWRLCLRMI-DDVA 188
            |:|.|:.||:..::.|:.|.||.|:|:.||.:.|.. .|  :..:.|.|..|....::|. ||.|
  Fly   156 AIRTNLTGTMRTIELAKQLKQLAAYIYCSTAFCNSN-NRGLIAEEVYKSQFDPYEMMKMAEDDSA 219

  Fly   189 DDGMLNALTRKLIMGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGF-SPSLM 252
            .:...:...:..|...||||||||||:|:|:......||..:.|||||...:|.|..|: ..:..
  Fly   220 WEDFTDQKCKGYIRDHPNTYTFTKNLSENLLMAEMSGLPAAIVRPSIVYGTLEHPMKGWVGNANS 284

  Fly   253 GAMGLFALVGAGILKTVYLGKDIRLDITPQDIGIKSMLCYTKMGYDI-YRQGPPADL-------- 308
            |.:|..|....||.:|:....:..:||.|.|..|.|.|.   ||:.: .|:....::
  Fly   285 GHLGFLAGFVKGIFRTMCGNANAVIDIIPCDYVINSSLV---MGWYVGTRKLEQPEIIHCTSGEV 346

  Fly   309 -PVFLSSSCT--------HVPHTFTQIAEQMDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLVF 364
             |:.|:..||        |.|::|           :|:.|...:|           .|.|....:
  Fly   347 NPLNLAEFCTIINDSVERHPPNSF-----------VWKPVTKLRN-----------GWRYNLFFY 389

  Fly   365 TKQILPALILDLLLRIFGQKPVLMSAVRKAYQTLEVMQ------------PFMFNNWDSPGVSDM 417
            ...:|||::..:..::||    :......||:.:.|.|            .|.::..::..:|
  Fly   390 LFHLLPAMVFIIPEKLFG----IGMPQHTAYEYMRVFQKGTKAFDYFLDKDFRYSLKNALRIS-- 448

  Fly   418 ETLSKHGEGSAFNFDAFNHPDIHGLVIQSC------SNMLHSIRTHLLREDPKTLERSKRILRIK 476
             .|....:...:||||           ..|      ...|..||....:|...|.:..:...  |
  Fly   449 -ALIPESDRRRYNFDA-----------SQCDWSEFIDRCLIGIRRFYFKESAVTTDWHRNYW--K 499

  Fly   477 VF--------------LYRLLRL-----------FLLYKLILWL 495
            ||              ||..|.|           .|::..::||
  Fly   500 VFNVLYYAGYVVIFAVLYFALTLTLGLQIGLTLAVLIWGFLVWL 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FarO	NP_652021.1	FAR-N_SDR_e	18..328	CDD:187547	112/335 (33%)
FarO	NP_652021.1	FAR_C	379..>410	CDD:296071	7/42 (17%)
CG8303	NP_001286495.1	FAR-N_SDR_e	46..366	CDD:187547	109/328 (33%)
CG8303	NP_001286495.1	Sterile	392..485	CDD:281068	20/110 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466736
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.950