DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment FarO and CG1441

DIOPT Version :9

Sequence 1:	NP_652021.1	Gene:	FarO / 45707	FlyBaseID:	FBgn0023550	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_610535.1	Gene:	CG1441 / 36029	FlyBaseID:	FBgn0033464	Length:	517	Species:	Drosophila melanogaster

Alignment Length:	515	Identity:	155/515 - (30%)
Similarity:	260/515 - (50%)	Gaps:	36/515 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GEME--------EFFEDSEIFVTGGSGVVGKALVEKLLRSC-NVRRIYVLLRPRKQLTAEQRLVR 62
            ||::        |.|:...:|:|||:|.:||.||||||||| .::|||:|:||:|....::|:..
  Fly    18 GEIDDNEVDRIAECFKGRSLFITGGTGFLGKVLVEKLLRSCGGLKRIYLLIRPKKGKDPQERIKD 82

  Fly    63 LRQATVFHVLAVQKPEE--LDKIVAVPGDVSLPGLGIDPSMMQRMK-GVSLVYHCAATVRFDEPL 124
            :.|..:|..:...:.||  |.::||:.|||..|||||....::.:: .||:||||||||||||||
  Fly    83 IFQNVLFDQVKQMRGEEHILQQVVAIAGDVLSPGLGISEKDLETLRQEVSIVYHCAATVRFDEPL 147

  Fly   125 REAVRLNVGGTLEALKFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSSPMDWRLCLRMIDDVAD 189
            |.||.:|..||...|:.|.||..|..|.:.||.|.:.::..:..|.|..|.|....::..:.:.|
  Fly   148 RNAVFMNTRGTKYMLELALTLKHLDFFAYCSTAYCHLHVKTLYEKPYDPPADPHKVMQACEWLTD 212

  Fly   190 DGMLNALTRKLIMGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGA 254
            |.:. .:.||::...||||.:||:|||:||.:....||.::.|||||:...::|.||::.::.|.
  Fly   213 DEVA-TIERKVLGAIPNTYAYTKSLAEALVVEKFEELPAVILRPSIVIPIWKEPIPGWTDNINGP 276

  Fly   255 MGLFALVGAGILKTVYLGKDIRLDITPQDIGIKSMLCYTKMGYDIYRQ---GPPADLPVFLSSSC 316
            .||....|.|:::|:|.......|..|.|:.:..:|..:      :|.   |......|...:|.
  Fly   277 TGLLIGAGKGVIRTMYCNSSGYGDFLPVDVAVNGILVAS------WRNITAGTDKTNRVAHMTSS 335

  Fly   317 THVPHTFTQIAEQMDTLDLW---RDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALILDLLL 378
            ..:..::.:|.|    |..|   ..|........||.......|.:...:...|.:|||.:|.||
  Fly   336 NDIKVSWAEIIE----LGRWVIENKVPLNGVAWYPGGSMKSNYWVHFICMVLFQWMPALFVDALL 396

  Fly   379 RIFGQKPVLMSAVRKAYQTLEVMQPFMFNNW--DSPGVSDMETLSKHGEGSAFNFDAFNHPDIHG 441
            .|....|||.....:.|:..||.:.:..|.|  |:.....:..|..:.|...:..:     .|..
  Fly   397 WILRYPPVLCRVQNRIYKGFEVFEYYANNVWNFDNSEAVKLRKLMNNKERRTYVIE-----KIEL 456

  Fly   442 LVIQSCSNMLHSIRTHLLREDPKTLERSKRILRIKVFLYRLLRLFLLYKLILWLWRSYLA 501
            .:|...:|.:...|..:|:|..:::..::|.:::...:.::.:...::.::..|:|.:.|
  Fly   457 DLIDYFTNCVLCARRLILKESDESIPAARRHMKVMWVVDKVYKGIWIFGILYMLYRCFFA 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FarO	NP_652021.1	FAR-N_SDR_e	18..328	CDD:187547	115/316 (36%)
FarO	NP_652021.1	FAR_C	379..>410	CDD:296071	9/32 (28%)
CG1441	NP_610535.1	PLN02996	24..464	CDD:215538	145/455 (32%)
		FAR-N_SDR_e	35..348	CDD:187547	116/323 (36%)
		Sterile	385..475	CDD:281068	23/94 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466740
Domainoid	1	1.000	159	1.000	Domainoid score	I1277
eggNOG	1	0.900	-	-		E1_COG3320
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	1	1.000	-	-		mtm964
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11011
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
	9	8.850