DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FarO and si:dkey-97m3.1

DIOPT Version :9

Sequence 1:	NP_652021.1	Gene:	FarO / 45707	FlyBaseID:	FBgn0023550	Length:	504	Species:	Drosophila melanogaster
Sequence 2:	NP_001076558.1	Gene:	si:dkey-97m3.1 / 100034578	ZFINID:	ZDB-GENE-060503-367	Length:	515	Species:	Danio rerio

Alignment Length:	521	Identity:	157/521 - (30%)
Similarity:	262/521 - (50%)	Gaps:	64/521 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GEMEEFFEDSEIFVTGGSGVVGKALVEKLLRSC-NVRRIYVLLRPRKQLTAEQRLVRLRQATVFH 70
            |.:.|::....:.:||.:|.:||.||||||||| :|..:|:|:||:...:..:|:..:.:..:|.
Zfish     2 GSISEWYAGKNVLITGATGFMGKVLVEKLLRSCPDVNALYILVRPKAGQSMSERVQDMMKCKLFD 66

  Fly    71 VLAVQKPEELDKIVAVPGDVSLPGLGIDPSMMQRMKG-VSLVYHCAATVRFDEPLREAVRLNVGG 134
            .:....||...||:|:..::..|||.|....::.:.. |.:|:|||||:||||||:.|::|||..
Zfish    67 RVREDNPEFHQKIIAISSELMQPGLAISAQDVETLTSRVHIVFHCAATIRFDEPLKHALQLNVMA 131

  Fly   135 TLEALKFAETLPQLRAFIHVSTFYSNPYLTRVEPKYYSSPMDWRLCLRMIDDV--ADDGMLNALT 197
            |.:.|..|:.:.||:||||:||.|:|.....::...|..|::.|   ::||.:  .|:.::..:|
Zfish   132 TQQLLSLAQQMQQLQAFIHISTAYANCNRRHIDELIYPPPVEPR---KLIDSLEWMDESIIRDIT 193

  Fly   198 RKLIMGFPNTYTFTKNLAESLVNDYRHRLPVIVYRPSIVLFAVEDPSPGFSPSLMGAMGLFALVG 262
            .:||..:|||||:||.|||.:|.....:|.|.:.|||||..:.::|.||:..:..|..|:|...|
Zfish   194 PRLIGDWPNTYTYTKALAECVVQQESAKLNVGIVRPSIVGASWQEPFPGWIDNFNGPSGVFIAAG 258

  Fly   263 AGILKTVYLGKDIRLDITPQDIGIKSMLC---YTKMGYDIYRQGPPADLPVFLSSSCT------- 317
            .|||:|:....|...|:.|.|:.|...|.   ||.:       ..|....|:   :||
Zfish   259 KGILRTMRASNDAVADLIPVDVVINLTLAAGWYTAV-------NKPKTALVY---NCTTGGINPF 313

  Fly   318 -------HVPHTFTQ-IAEQMDTLDLWRDVAFEKNLMIPGCHYTDKRWAYQFLVFTKQILPALIL 374
                   ||..||.: ..||          ||.:    |..:.|.....||:.:.....:|||:.
Zfish   314 HWGEIEHHVMSTFKRNPLEQ----------AFRR----PNANITSNYLIYQYWILVSHKVPALLY 364

  Fly   375 DLLLRIFGQKPVLMSAVRKAYQTLEVMQPFMFNNWD--SPGVSDMETLSKHGEGSAFNFDA--FN 435
            |||||:.|.||.:|....:.::.:.:::.|...:|:  |..::.:.......:...||||.  .|
Zfish   365 DLLLRLSGHKPQMMRIFNRLHKAIGLLEYFSSQDWEWNSDNMNMLMAQLSTDDRKIFNFDVRQLN 429

  Fly   436 HPDIHGLVIQSCSNMLHSIRTHLLREDPKTLERSKRILRIKVFLYRLLRLFLLYKLILWLWRSYL 500
            .|:.       ..|.....:.::|.||...:..:::.||    ..|.:|......|::::||.::
Zfish   430 WPEY-------IENYCIGTKKYVLNEDMSDIPAARQHLR----KLRNIRYTFNTVLLVFIWRVFI 483

  Fly   501 A 501
            |
Zfish   484 A 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FarO	NP_652021.1	FAR-N_SDR_e	18..328	CDD:187547	114/331 (34%)
FarO	NP_652021.1	FAR_C	379..>410	CDD:296071	6/30 (20%)
si:dkey-97m3.1	NP_001076558.1	PLN02996	2..446	CDD:215538	146/477 (31%)
		FAR-N_SDR_e	11..330	CDD:187547	114/331 (34%)
		Sterile	357..447	CDD:281068	22/96 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593287
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3320
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D221518at33208
OrthoFinder	1	1.000	-	-		FOG0000172
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100550
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X145
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.650