Protein Alignment Cyp4d14 and ERG5

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_013728.1
• Gene: ERG5 / 855029
• SGDID: S000004617
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 530
• Identity: 122/530 - (23%)
• Similarity: 212/530 - (40%)
• Gaps: 106/530 - (20%)

  Fly     2 YLELFAILLATALAWD---YMRKRRHNKMYAEAGIRGP--KSYPLVGNAPLLINESPK------- 54
            ||::||.|:...|.||   |..|:        ..|.||  |.:|::|  |.|.:..||
Yeast    45 YLKIFATLICILLVWDQVAYQIKK--------GSIAGPKFKFWPIIG--PFLESLDPKFEEYKAK 99

  Fly    55 ------SKSSIFDMQFRLIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLV- 112
                  |..|||. :|.:||. .:::..::|..|.|:                  |..:..:.|
Yeast   100 WASGPLSCVSIFH-KFVVIAS-TRDLARKILQSSKFV------------------KPCVVDVAVK 144

  Fly   113 -----NWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVIN 172
                 ||     :...||.....||.:...|..:.|..::...:|    ::.|..|:....:..|
Yeast   145 ILRPCNW-----VFLDGKAHTDYRKSLNGLFTKQALAQYLPSLEQ----IMDKYMDKFVRLSKEN 200

  Fly   173 MFPV--------ACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFT 229
            .:..        ..|||:.:  .:..|..|......:......:.||:          |:.::|.
Yeast   201 NYEPQVFFHEMREILCALSL--NSFCGNYITEDQVRKIADDYYLVTAA----------LELVNFP 253

  Fly   230 MKLFYPKLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGG------DADAALLNDVGQKRRMA 288
            :.:.|.|.......|...|..|.|..     ::.:..||.||      ||...|::|.......
Yeast   254 IIIPYTKTWYGKKTADMAMKIFENCA-----QMAKDHIAAGGKPVCVMDAWCKLMHDAKNSNDD- 312

  Fly   289 LLDVLLKSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIG 353
                  .|.|.....:|.:|.|.|.||:|...|.::|...:...::|..|:|.|::.:|...|..
Yeast   313 ------DSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRN 371

  Fly   354 DDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQD-TVLDGKLIPADSNVIILIYHAQ 417
            :|.|..:.:.|:.::||...||||:||..|.|.::...:.:: .|......|..:.:|..:|.|.
Yeast   372 NDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPAL 436

  Fly   418 RDPDYFPDPEKFIPDRFSMERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVR----HF 478
            .||:.:.:|::|||:|:....|...:...:..|..||..|:||.:.|:...:.:.|...    |.
Yeast   437 HDPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCLGQTYVMITFAALLGKFALYTDFHH 501

  Fly   479 ELLPLGEEVQ 488
            .:.||.|:::
Yeast   502 TVTPLSEKIK 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	95/443 (21%)
ERG5	NP_013728.1	CYP61_CYP710	103..522	CDD:410703	102/462 (22%)