DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d14 and CYP735A2

DIOPT Version :9

Sequence 1:	NP_001259179.1	Gene:	Cyp4d14 / 45706	FlyBaseID:	FBgn0023541	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_176882.1	Gene:	CYP735A2 / 843031	AraportID:	AT1G67110	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	552	Identity:	137/552 - (24%)
Similarity:	238/552 - (43%)	Gaps:	97/552 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 YLELFAILLATALAWD-----YMRKRRHNKMYAEAGIRGPKSYPLVGN----APLLINESPKSKS 57
            |:.:..:.|...:.:|     ::..||..|.....||.|||...|.||    :.:|.:.:....|
plant     9 YVLVIVMTLILRVLYDSICCYFLTPRRIKKFMERQGITGPKPRLLTGNIIDISKMLSHSASNDCS 73

  Fly    58 SI-FDMQFRLI-------AEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNW 114
            || .::..||:       .::||........|......:::||:.:::....:...       :|
plant    74 SIHHNIVPRLLPHYVSWSKQYGKRFIMWNGTEPRLCLTETEMIKELLTKHNPVTGK-------SW 131

  Fly   115 L---------GDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTV 170
            |         |.|||::.|:.|..:|.:..|||....|:.:.:...:.:..|.::|.... |:.|
plant   132 LQQQGTKGFIGRGLLMANGEAWHHQRHMAAPAFTRDRLKGYAKHMVECTKMMAERLRKEV-GEEV 195

  Fly   171 INMFPVACLCAMDIIAETAMGVKIN--AQLQPQFTYVQSVTT---------ASAMLAERFMNPLQ 224
            .....:..|.| |||:.|..|...:  .:|....|.:|.:..         .|..|..::...::
plant   196 EIGEEMRRLTA-DIISRTEFGSSCDKGKELFSLLTVLQRLCAQATRHLCFPGSRFLPSKYNREIK 259

  Fly   225 RLDFTMKLFYPKLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMAL 289
            .|...::....:::|...|:|:                :.::.:.|.|....|||.:...:..
plant   260 SLKTEVERLLMEIIDSRKDSVE----------------IGRSSSYGDDLLGLLLNQMDSNKNN-- 306

  Fly   290 LDVLLKSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGD 354
            |:|.:             |.:|..||.|.||:||:..:.:|..|||.:|..|..|..|||.|.|.
plant   307 LNVQM-------------IMDECKTFFFTGHETTSLLLTWTLMLLAHNPTWQDNVRDEVRQVCGQ 358

  Fly   355 DKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNV---IILIYHA 416
            | ..| :::.|..|..|..||.|||||:|...::.|...:|..|...:||...::   ::.|:|:
plant   359 D-GVP-SVEQLSSLTSLNKVINESLRLYPPATLLPRMAFEDIKLGDLIIPKGLSIWIPVLAIHHS 421

  Fly   417 Q----RDPDYFPDPEKFIPDRFSMERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRH 477
            .    .|.:.| :||:|....|:..|.       :.||:|||||||||.|||:|.|..::.:|..
plant   422 NELWGEDANEF-NPERFTTRSFASSRH-------FMPFAAGPRNCIGQTFAMMEAKIILAMLVSK 478

  Fly   478 FELLPLGEEVQ--PVLNVILRSTTGINCGLKP 507
            |. ..:.|..:  |::.:.::...|:...|||
plant   479 FS-FAISENYRHAPIVVLTIKPKYGVQLVLKP 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	124/495 (25%)
CYP735A2	NP_176882.1	PLN02290	2..511	CDD:215164	137/552 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960