DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4d14 and CYP86C4

DIOPT Version :9

Sequence 1:	NP_001259179.1	Gene:	Cyp4d14 / 45706	FlyBaseID:	FBgn0023541	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_172774.1	Gene:	CYP86C4 / 837873	AraportID:	AT1G13150	Length:	529	Species:	Arabidopsis thaliana

Alignment Length:	563	Identity:	132/563 - (23%)
Similarity:	233/563 - (41%)	Gaps:	111/563 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 YLELFAILLAT--ALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKSKSSIFDMQF 64
            :|.||.:||:.  ...:..:|::..||       |||..:|:.|              ...:..|
plant    10 HLSLFDLLLSLLGLFVFCCLREKLTNK-------RGPMLWPVFG--------------ITLEFFF 53

  Fly    65 RLIAEFG------KNIKTQML-------GESGFMTADSKMIEAIMSSQ-QTIQKNNLYSLLVN-W 114
            .:...:|      |..:...|       |..|.:|.....:|.::.:. :...|...:....| .
plant    54 HINDVYGWVTRSLKKCRGTFLYRGVWLDGSYGAVTCVPANVEYMLKTNFKNFPKGTFFKSRFNDL 118

  Fly   115 LGDGLLISQGKKWFRRRKIITPAFH--------------------FKILEDFVEVFDQQSATMVQ 159
            |.:|:..:....|..:|:||....|                    .|::|.|.:   .|.|..:|
plant   119 LEEGIFNADDDSWKEQRRIIITEMHSTGFVEHSFQTTQHLVRKKLLKVMESFAK---SQEAFDLQ 180

  Fly   160 KLYDRADGKTVINMFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFM---- 220
            .::.|.       .|.:.||..:....|| :.|.:     ||..:.::...|:.....|||
plant   181 DVFLRL-------TFDIICLAGLGADPET-LAVDL-----PQVPFAKAFEEATESTLFRFMIPPF 232

  Fly   221 --NPLQRLDFTMKLFYPKLLDKLNDAVKNMHDFTNSVITER-RELLQKAIADG-GDADAALLNDV 281
              .|::.||    ..|.|   .|..||..:|.|.:.:|.:| .||.::...|. .|..:.::...
plant   233 IWKPMRFLD----TGYEK---GLRIAVGVVHGFVDKMIVDRICELKEEETLDNRSDVLSRIIQIE 290

  Fly   282 GQKRRMALLDVLLKSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQ 346
            ..||         ::.||  |.:....|:...:|:..|.||::.::::.|:::.:||||:.::..
plant   291 SHKR---------ENEID--PSTIRFFRQFCTSFILAGRDTSSVALSWFCWVIQKHPEVENKIIC 344

  Fly   347 EVRDVIGDDKSAPV-------TMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVL-DGKLI 403
            |:|:::.....:|.       |:|.|..:.||:..:.|:|||||.:|:..:...:|.|| ||..:
plant   345 EIREILRQRGDSPTSKNESLFTVKELNNMVYLQAALSETLRLFPPIPMEMKQAIEDDVLPDGTFV 409

  Fly   404 PADSNVIILIYHAQR-DPDYFPDPEKFIPDRFSMERK-GEISPFAYTPFSAGPRNCIGQKFAMLE 466
            ...|.|...||...| :..:..|.|.|.|:|:....| .....|.|..|:||||.|||:.||.|:
plant   410 RKGSRVYFSIYAMGRMESIWGKDCEIFRPERWIQAGKFVSDDQFKYVVFNAGPRLCIGKTFAYLQ 474

  Fly   467 MKSTISKMVRHFELLPLGEEV-QPVLNVILRSTTGINCGLKPR 508
            ||...:.::..:.:..:.:.| .|.:...|....|:...:.||
plant   475 MKMIAASVLLRYSIKVVQDHVIAPRVTTNLYMKYGLKVTITPR 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	119/508 (23%)
CYP86C4	NP_172774.1	CYP86A	73..510	CDD:410687	113/470 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010