DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d14 and CYP87A2

DIOPT Version :9

Sequence 1:	NP_001259179.1	Gene:	Cyp4d14 / 45706	FlyBaseID:	FBgn0023541	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001184974.1	Gene:	CYP87A2 / 837830	AraportID:	AT1G12740	Length:	478	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	99/516 - (19%)
Similarity:	185/516 - (35%)	Gaps:	105/516 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 AILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNA------------PLLINESPKSKSSI 59
            ::||.:...|.|..:....:.....|..|   :||:|.:            |..|.|..|:.
plant     9 SLLLISITHWVYSWRNPKCRGKLPPGSMG---FPLLGESIQFFKPNKTSDIPPFIKERVKND--- 67

  Fly    60 FDMQFRLIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDGLLISQG 124
            .||     ..:|...||.::|....::.|:.:...:.:     |:...:.   :|..|......|
plant    68 VDM-----CRYGPIFKTNLVGRPVIVSTDADLSYFVFN-----QEGRCFQ---SWYPDTFTHIFG 119

  Fly   125 KK----------WFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACL 179
            ||          .:.:..::|...|..:.:...:|  :.:|....:|:...|.   :.:......
plant   120 KKNVGSLHGFMYKYLKNMVLTLFGHDGLKKMLPQV--EMTANKRLELWSNQDS---VELKDATAS 179

  Fly   180 CAMDIIAETAMG---VKINAQLQPQFTYVQSVTTASAMLAERFMNP-------LQRLDFTMKLFY 234
            ...|:.|:..:.   .|.:..|:..|     |.....:::..|..|       ||.....||:..
plant   180 MIFDLTAKKLISHDPDKSSENLRANF-----VAFIQGLISFPFDIPGTAYHKCLQGRAKAMKMLR 239

  Fly   235 PKLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTID 299
            ..|.::..:..||..||.:.||.|    :||                                 :
plant   240 NMLQERRENPRKNPSDFFDYVIEE----IQK---------------------------------E 267

  Fly   300 GAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVI--GDDKSAPVTM 362
            |..|:.:...:.:...:|...:||:.::......|:..|||..|:.:|...::  .:|..:.:|.
plant   268 GTILTEEIALDLMFVLLFASFETTSLALTLAIKFLSDDPEVLKRLTEEHETILRNREDADSGLTW 332

  Fly   363 KLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYFPDPE 427
            :....:.|....|.|:.||...||.|.|...:|.......|||...|::.......:|:.:.||.
plant   333 EEYKSMTYTFQFINETARLANIVPAIFRKALRDIKFKDYTIPAGWAVMVCPPAVHLNPEMYKDPL 397

  Fly   428 KFIPDRFSMERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQ 488
            .|.|.|:...:....|.. :..|..|.|.|:|..|..|:|.:.:..:|..:.    .||::
plant   398 VFNPSRWEGSKVTNASKH-FMAFGGGMRFCVGTDFTKLQMAAFLHSLVTKYR----WEEIK 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	94/489 (19%)
CYP87A2	NP_001184974.1	p450	4..475	CDD:299894	99/516 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920