DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d14 and CYP709B3

DIOPT Version :9

Sequence 1:	NP_001259179.1	Gene:	Cyp4d14 / 45706	FlyBaseID:	FBgn0023541	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_194501.1	Gene:	CYP709B3 / 828885	AraportID:	AT4G27710	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	528	Identity:	131/528 - (24%)
Similarity:	219/528 - (41%)	Gaps:	99/528 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LELFAILLATALAWD-----YMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKSKSS---- 58
            |.:..:|...:..|.     .:|....:|.:.:.||.|||...|.||    ::|..|.|..
plant    10 LTIVLLLFVVSKIWKACWILLLRPLMLSKRFKKQGISGPKYKILYGN----LSEIKKMKKEADLC 70

  Fly    59 ------------IFDMQFRLIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQ-----QTIQKNN 106
                        :|....:.::::|.........:.....::.::.:.::||:     ..:::..
plant    71 VLDPNSNDIFPRVFPQYHQWMSQYGDTFLFWTGTKPTIYISNHELAKQVLSSKFGFTIIPVKRPE 135

  Fly   107 LYSLLVNWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYD-----RAD 166
            ::.|    .|.||...||..|.|.|:|:.|||..    |.::...|.......::::     |.:
plant   136 VFIL----FGKGLSFIQGDDWIRHRRILNPAFSM----DRLKAMTQPMGDCTLRIFEEWRKQRRN 192

  Fly   167 GKTVINM-----FPVACLCAMDIIAETAMGVK-------INAQLQPQFTYVQSVTTASAMLAERF 219
            |:.:|.:     |.   ....||||.||.|..       ..:|.:.:..|:.|:|..       |
plant   193 GEVLIKIEISKEFH---KLTADIIATTAFGSSYAEGIELCRSQTELEKYYISSLTNV-------F 247

  Fly   220 MNPLQRLDFTMKLFYPKLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGD-----ADAALLN 279
            :...|.|.....|...:|..|:.:::|.       :|..|.:...|....|.|     ..||..|
plant   248 IPGTQYLPTPTNLKLWELHKKVKNSIKR-------IIDSRLKSKCKTYGYGDDLLGVMLTAAKSN 305

  Fly   280 DVGQKRRMALLDVLLKSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARV 344
            :..:|.||                  |:|.||...|.:.|..||:..:.:|..||:.|...|.::
plant   306 EYERKMRM------------------DEIIEECKNFYYAGQGTTSILLTWTTMLLSLHQGWQEKL 352

  Fly   345 FQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNV 409
            .:||.:..|.|| .|.| ....:||.:..|:.|||||:..|..|.|..:||..:....||..:::
plant   353 REEVFNECGKDK-IPDT-DTFSKLKLMNMVLMESLRLYGPVIKISREATQDMKVGHLEIPKGTSI 415

  Fly   410 IILIYHAQRDPDYF-PDPEKFIPDRFSME-RKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTIS 472
            ||.:....||...: .|.|:|.|.||... .:..|.|.|..|||.|||.||.:.|||:|.|:.::
plant   416 IIPLLKMHRDKAIWGEDAEQFNPLRFENGISQATIHPNALLPFSIGPRACIAKNFAMVEAKTVLT 480

  Fly   473 KMVRHFEL 480
            .:::.|:|
plant   481 MILQQFQL 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	124/492 (25%)
CYP709B3	NP_194501.1	p450	9..517	CDD:299894	131/528 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960