DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d14 and CYP83A1

DIOPT Version :9

Sequence 1:	NP_001259179.1	Gene:	Cyp4d14 / 45706	FlyBaseID:	FBgn0023541	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_193113.1	Gene:	CYP83A1 / 827011	AraportID:	AT4G13770	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	114/537 - (21%)
Similarity:	225/537 - (41%)	Gaps:	109/537 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKSKSSIFDMQFRLIAEFGK 72
            :.||..|.: ::.::...|.|...  .||...|::||...|...:|:          |..|.:.|
plant     9 VALAAVLLF-FLYQKPKTKRYKLP--PGPSPLPVIGNLLQLQKLNPQ----------RFFAGWAK 60

  Fly    73 N---IKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLG-----DGLLISQGKK--- 126
            .   |.:..:|        |:.:..|.|::  :.|..|.:..||:..     ....||.|::
plant    61 KYGPILSYRIG--------SRTMVVISSAE--LAKELLKTQDVNFADRPPHRGHEFISYGRRDMA 115

  Fly   127 ------WFR--RRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMD 183
                  ::|  |:..:...|....:..|..|.::::..|:.|:...||...|:::..:.......
plant   116 LNHYTPYYREIRKMGMNHLFSPTRVATFKHVREEEARRMMDKINKAADKSEVVDISELMLTFTNS 180

  Fly   184 IIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYP--KLLDKLNDAVK 246
            ::...|.|.|.|...:....:::.:....::|.:.|.:.          |:|  ..||.|:....
plant   181 VVCRQAFGKKYNEDGEEMKRFIKILYGTQSVLGKIFFSD----------FFPYCGFLDDLSGLTA 235

  Fly   247 NMHDFTNSVITERRE-LLQKAIADGGDADAALLNDVGQKRRM-----ALLDVLL---KSTIDGAP 302
            .|.:     ..||:: .:|:.:           |:....:|:     :::|:|:   |.....:.
plant   236 YMKE-----CFERQDTYIQEVV-----------NETLDPKRVKPETESMIDLLMGIYKEQPFASE 284

  Fly   303 LSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGE 367
            .:.|:::..:...:..|.||..:::.:....|.::|:|..:...|||:.:.:..|..||...:..
plant   285 FTVDNVKAVILDIVVAGTDTAAAAVVWGMTYLMKYPQVLKKAQAEVREYMKEKGSTFVTEDDVKN 349

  Fly   368 LKYLECVIKESLRLFPSVP-IIGRYISQDTVLDGKLIPADSNVIILIYHAQRD-PDYFPDPEKFI 430
            |.|...::||:||:.|.:| :|.|...|||.:.|..|||.:.|.:..:...|| .::.|:|::|.
plant   350 LPYFRALVKETLRIEPVIPLLIPRACIQDTKIAGYDIPAGTTVNVNAWAVSRDEKEWGPNPDEFR 414

  Fly   431 PDRF---SMERKGEISPFAYTPFSAGPRNCIGQKF--AMLEMKSTISKMVRHFELLPLGEEVQPV 490
            |:||   .::.||  :.:.:.||.:|.|.|.|.:.  ||||:                     |.
plant   415 PERFLEKEVDFKG--TDYEFIPFGSGRRMCPGMRLGAAMLEV---------------------PY 456

  Fly   491 LNVILRSTTGINCGLKP 507
            .|::|.....:..|:||
plant   457 ANLLLSFNFKLPNGMKP 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	103/491 (21%)
CYP83A1	NP_193113.1	PLN02966	1..502	CDD:178550	114/537 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910