DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d14 and CYP72A7

DIOPT Version :9

Sequence 1:	NP_001259179.1	Gene:	Cyp4d14 / 45706	FlyBaseID:	FBgn0023541	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_188079.1	Gene:	CYP72A7 / 820689	AraportID:	AT3G14610	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	127/512 - (24%)
Similarity:	221/512 - (43%)	Gaps:	72/512 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ILLATALAWD-------YMRKRRHNKMYAEAGIRGPKSYPLVG----NAPLLINESPKSKSSIFD 61
            :|:|..:.|.       :::.:.........|:.|....||||    |..:::....|..:...|
plant    11 VLVAVVVLWTWRIVKWVWIKPKMLESSLKRQGLTGTPYTPLVGDIKRNVDMMMEARSKPINVTDD 75

  Fly    62 MQFRLIAEFGKNIKTQMLGESG------------FMTADSKMIEAIMSSQQTIQKNNLYSLLVNW 114
            :..||:.     :..:||...|            .:..:.:.|:.:.:.....:|.:.:. |:..
plant    76 ITPRLLP-----LALKMLNSHGKTFFIWIGPLPTIVITNPEQIKEVFNKVNDFEKASTFP-LIRL 134

  Fly   115 LGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMV---QKLYDRADGKTVINMFPV 176
            |..||...:|.||...|:||.||||.:.:::.:..|....:.:|   :||:...:....::::|.
plant   135 LAGGLASYKGDKWASHRRIINPAFHLEKIKNMIPAFYHCCSEVVCQWEKLFTDKESPLEVDVWPW 199

  Fly   177 ACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDKL 241
            ......|:|:.||.|        ..:...|.:......|||......::.......|||...::.
plant   200 LVNMTADVISHTAFG--------SSYKEGQRIFQLQGELAELIAQAFKKSYIPGSRFYPTKSNRR 256

  Fly   242 NDAVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTID---GAPL 303
            ..|:....|.....|..:||..::|               |:.....||.:||:|..:   |..:
plant   257 MKAIDREVDVILRGIVSKREKAREA---------------GEPANDDLLGILLESNSEESQGNGM 306

  Fly   304 SNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGEL 368
            |.:|:.:|...|.|.|.:||:..:.:|..||:.|.:.|||..:||..|:|::...  .|:.|..|
plant   307 SVEDVMKECKLFYFAGQETTSVLLVWTMVLLSHHQDWQARAREEVMQVLGENNKP--DMESLNNL 369

  Fly   369 KYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYFPD------PE 427
            |.:..:..|.|||:|.|..:.|.::::..|....:||...:.:.....|||.:.:.|      ||
plant   370 KVMTMIFNEVLRLYPPVAQLKRVVNKEMKLGELTLPAGIQIYLPTILVQRDTELWGDDAADFKPE 434

  Fly   428 KFIPDRFSMERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVR--HFELLP 482
            :| .|..|...|.::|.|   ||..|||.||||.|||||.|..::.:::  .|||.|
plant   435 RF-RDGLSKATKNQVSFF---PFGWGPRICIGQNFAMLEAKMAMALILQKFSFELSP 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	123/479 (26%)
CYP72A7	NP_188079.1	p450	21..512	CDD:299894	124/502 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960