DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4d14 and CYP96A5

DIOPT Version :9

Sequence 1:	NP_001259179.1	Gene:	Cyp4d14 / 45706	FlyBaseID:	FBgn0023541	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_179782.1	Gene:	CYP96A5 / 816727	AraportID:	AT2G21910	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	121/548 - (22%)
Similarity:	234/548 - (42%)	Gaps:	90/548 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LELFAILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLL------INESPKSKSSIFD 61
            :|:|..||........:.|:.|...        |:::|::|..|.:      ||:.......:.:
plant     7 VEVFIALLVFFFFHFLIHKKSHQIT--------PRNWPVLGMLPGVLVMLHRINDYVAEILEVSN 63

  Fly    62 MQFRLIAEF--GKNIKTQMLGESGFMTADSKMIEAIMSSQ-QTIQKNNLYSLLVNWLGDGLLISQ 123
            :.|.....:  |.|:         .:|||...|:.:.||. ....|...:..:.::||:|:..:.
plant    64 LTFAFKGPWFSGMNM---------LITADPSNIQHVFSSNFSNYDKGPEFKEMFDFLGNGIFTAD 119

  Fly   124 GKKWFRRRK---IITPAFHF----------KILEDFVEVFDQQSATMVQKLYDRADGKTVINMFP 175
            .|.|...||   ::.....|          ||....|.|.|.           .|:..||.::..
plant   120 SKLWEDMRKSALVVLSHQGFQSFSLRTITCKIKNGLVPVLDH-----------FAEANTVFDLQD 173

  Fly   176 VACLCAMDIIAETAMGV---KINAQLQPQFTYVQSVTTASAMLAERFMNP--LQRLDFTMKLFYP 235
            |....|.|:......|.   .::.:: |:..|.:::..|..::..|.:.|  |.:|...:.|...
plant   174 VFQRLAFDVTLTLVTGCDSSSLSIEM-PKNEYAKAMDDAEEVVVYRHVKPVVLWKLQNWIGLGEE 237

  Fly   236 KLLDKLNDAVKNMHDFTNS----VITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKS 296
            |.:.:.|.|      |..|    :..:|.|::......||:|.|.           .||.|.:..
plant   238 KKMKEANAA------FDRSCAKYISAKREEIISHHSNIGGEAHAE-----------DLLSVYMNL 285

  Fly   297 TIDGAPL--SNDD--IREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVR-DVIGDDK 356
            .|....|  .|||  :::.:.:||..|.|...:::.:..:||:::||...::.||:. ::.|...
plant   286 DISKYELLNPNDDNFLKDIIKSFMLAGRDAIATTLTWFFWLLSKNPEAVTKIRQEINTNLPGSGM 350

  Fly   357 SAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRY-ISQDTVLDGKLIPADSNVIILIYHAQRDP 420
            |  :....|.::.||...:.|||||:..:|...:. |.||.:..|.::..:..::..:|...|..
plant   351 S--LDADKLNKMVYLHGALCESLRLYAPIPFERKTPIKQDVLPSGHMVDKNWKILFSVYALGRMR 413

  Fly   421 DYF-PDPEKFIPDRFSMERKGEIS---PFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELL 481
            ..: .|..:|.|:|:..||.|.:.   .|.:..|::|||||:|:..:.|:||:...:::|::::.
plant   414 SVWGQDASEFKPERWISERNGGLKHEPSFKFFVFNSGPRNCLGKNLSFLQMKTVAVEIIRNYDIK 478

  Fly   482 PL-GEEVQPVLNVILRSTTGINCGLKPR 508
            .: |.:::|..::||....|:...:..|
plant   479 VVEGHKIEPASSIILHMKHGLKVTVSKR 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	110/496 (22%)
CYP96A5	NP_179782.1	p450	1..506	CDD:299894	120/546 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920