Protein Alignment Cyp4d14 and CYP26B1

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_063938.1
• Gene: CYP26B1 / 56603
• HGNCID: 20581
• Length: 512
• Species: Homo sapiens
• Alignment Length: 509
• Identity: 114/509 - (22%)
• Similarity: 188/509 - (36%)
• Gaps: 128/509 - (25%)

  Fly    34 RGPKSYPLVGNAPLLINESPKSKSSIFDMQFRLIAEFGKNIKTQMLGESGFMTADSKMIEAIM-- 96
            :|...:||:|.....:.:....:||..:       ::|...||.:||........::.:..|:
Human    51 KGSMGFPLIGETGHWLLQGSGFQSSRRE-------KYGNVFKTHLLGRPLIRVTGAENVRKILMG 108

  Fly    97 -----------SSQQTIQKNNLYSLLVNWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVF 150
                       |::..:..|.    :.|.:||   |.:.|     ||:.:..|..:.||.::.
Human   109 EHHLVSTEWPRSTRMLLGPNT----VSNSIGD---IHRNK-----RKVFSKIFSHEALESYLP-- 159

  Fly   151 DQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAML 215
                                                      ||...:|.......|...|..:.
Human   160 ------------------------------------------KIQLVIQDTLRAWSSHPEAINVY 182

  Fly   216 AERFMNPLQRLDFTMKLFYPKLL-------DKLNDAVKNMHDFTNSVIT--------------ER 259
            .|     .|:|.|.|.:   ::|       :.|....:....|.::|.:              :.
Human   183 QE-----AQKLTFRMAI---RVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPFSGYRRGIQA 239

  Fly   260 RELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTID-GAPLSNDDIREEVDTFMFEGHDTT 323
            |::|||.:.   .|....|.....|..:..||:|::|:.: |..::..::::.....:|..:.||
Human   240 RQILQKGLE---KAIREKLQCTQGKDYLDALDLLIESSKEHGKEMTMQELKDGTLELIFAAYATT 301

  Fly   324 TSSIAFTCYLLARHPEVQARVFQEVR-DVIGDDKSAPV--TMKL--LGELKYLECVIKESLRLFP 383
            .|:.......|.:||.|..::..|:| ..|......|.  |::|  |..|:||:|||||.:|||
Human   302 ASASTSLIMQLLKHPTVLEKLRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLF- 365

  Fly   384 SVPIIGRY--ISQDTVLDGKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMER-KGEISPF 445
             .||.|.|  :.|...|||..||...:|:..|.........|.|...|.|||||..| :.:...|
Human   366 -TPISGGYRTVLQTFELDGFQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRF 429

  Fly   446 AYTPFSAGPRNCIGQKFAMLEMK---------STISKMVRHFELLPLGEEVQPV 490
            .|.||..|.|.|:|:..|.|.:|         |......|.|..:.|...:.||
Human   430 HYLPFGGGVRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRITLVPVLHPV 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	108/472 (23%)
CYP26B1	NP_063938.1	CYP26B1	60..490	CDD:410730	111/500 (22%)