Protein Alignment Cyp4d14 and cyp46a1.1

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001018358.1
• Gene: cyp46a1.1 / 553543
• ZFINID: ZDB-GENE-050522-464
• Length: 501
• Species: Danio rerio
• Alignment Length: 488
• Identity: 135/488 - (27%)
• Similarity: 232/488 - (47%)
• Gaps: 48/488 - (9%)

  Fly    36 PKSYPLVGNAPLLINESPKSKSSIFDMQFRLIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQ 100
            |:...|:|::..|........:.|.|:......::|...:...|.....|....:..:.||.|.:
Zfish    42 PRDSFLLGHSSSLTKAVYSDNNLIHDLFLHWAEKYGPVYRINTLHYVTIMVYCPEATKTIMMSPK 106

  Fly   101 TIQKNNLYSLLVN-----WLGDGLLIS-QGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQ 159
            .|:...:|..|.|     :||:||:.: ....|:|:|:|:.|||....|...:..||:.|..::.
Zfish   107 YIKDPFVYKQLFNLFGKRFLGNGLITAVDHDMWYRQRRIMDPAFSSTYLRSLISTFDEMSERLMD 171

  Fly   160 KLYDRADGKTVINMFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQ 224
            ||.:.|:.||...|..:.....:|:|.:.|.||.:|...|....:..:|......:.....:|..
Zfish   172 KLEEMANNKTPAVMHDLVNCVTLDVICKVAFGVDLNLLNQKDSPFQNAVELCLKGMILDVRDPFF 236

  Fly   225 RLDFTMKLFYP---KLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRR 286
            ||       :|   ||:.::.:|.:.:.......|..|:    .|:.:|.|....:|..:
Zfish   237 RL-------FPKNWKLIQQVREATELLRKTGEKWIQNRK----TAVKNGEDVPKDILTQI----- 285

  Fly   287 MALLDVLLKSTIDGAPLSNDDIREEVD---TFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEV 348
                   |||..:....:..|:.:.:|   ||...|.:||.:.::|....|.|:||:..|...||
Zfish   286 -------LKSAEEENVNNTQDLEQMLDNFVTFFIAGQETTANQLSFAIMALGRNPEIYKRAKAEV 343

  Fly   349 RDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILI 413
            .:|:|..:.  ::.:.||:|.||..|:||:|||:|:.|...|::.:|.|::|..:|...:|:...
Zfish   344 DEVLGTKRE--ISNEDLGKLTYLSQVLKETLRLYPTAPGTNRWLHEDIVINGIKVPRGCSVMFSS 406

  Fly   414 YHAQRDPDYFPDPEKFIPDRFSMERKGEISP---FAYTPFSAGPRNCIGQKFAMLEMKSTISKMV 475
            |.:||...:|.||.||.|:||.:.     :|   :.|.|||.|||.|:||.||.:|.|..::|::
Zfish   407 YVSQRLEKFFKDPLKFDPERFDVN-----APKPYYCYYPFSLGPRTCLGQVFAQMEAKLVLAKLL 466

  Fly   476 RHFE--LLPLGEEVQPVLNVILRSTTGINCGLK 506
            :.||  |:| |:......|..||..:|:.|.:|
Zfish   467 QRFEFSLVP-GQSFDIKDNGTLRPKSGVICNIK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	127/448 (28%)
cyp46a1.1	NP_001018358.1	CYP46A1-like	66..495	CDD:410706	128/459 (28%)