Protein Alignment Cyp4d14 and cyp51a1

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001016194.1
• Gene: cyp51a1 / 548948
• XenbaseID: XB-GENE-985396
• Length: 499
• Species: Xenopus tropicalis
• Alignment Length: 507
• Identity: 124/507 - (24%)
• Similarity: 214/507 - (42%)
• Gaps: 62/507 - (12%)

  Fly    14 LAWDYMRKRRHNKMYAEAGIRGPKSYP--LVGNAPLLINESPKSKSSIFDMQFRLIAEFGKNIKT 76
            ||..|:.|.....:.||.  .|...||  :..|.|.|.:.....||.|..:: ....::|.....
 Frog    33 LALAYVSKLAFKHLQAED--PGNVKYPPFISSNIPFLGHAIAFGKSPISFLE-NAYDKYGPVFSF 94

  Fly    77 QMLGESGFMTADSKMIEAIMSSQ-QTIQKNNLYSLLVN-WLGDGLLISQGKKWF-RRRKIITPAF 138
            .|:|::......|.....:.:|: :.:...::||.|.. ..|.|:........| .::|::....
 Frog    95 TMVGKTFTYLVGSDAAALLFNSKNEDLNAEDVYSRLTTPVFGKGVAYDVPNPIFLEQKKMLKTGL 159

  Fly   139 HFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAETAM----GVKINAQLQ 199
            :....:..|::.::::    |:.::|.....|.|:|.    ...::|..||.    |.:|.:.|.
 Frog   160 NIAHFKTHVQMIEEET----QEYFERWGDSGVRNLFE----ALSELIILTASRCLHGKEIRSMLN 216

  Fly   200 PQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDKLNDAVKNMHDFTNSVITERRELLQ 264
                  :.|....|.|...|.:....|...:.|...:..|:.:..:||:.   ..||.:||.
 Frog   217 ------ERVAQLYADLDGGFTHAAWLLPGWLPLPSFRRRDRAHREIKNIF---YQVIQKRRN--- 269

  Fly   265 KAIADGGDADAALLNDVGQKRRMALLDVLLKSTI-DGAPLSNDDIREEVDTFMFEGHDTTTSSIA 328
                             ..:|...:|..||.:|. ||.||::|:|...:...:..|..|::::.|
 Frog   270 -----------------SAEREDDMLQTLLDATYKDGTPLNDDEIAGMLIGLLLAGQHTSSTTSA 317

  Fly   329 FTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYIS 393
            :..:.||::..:||:.|.|.:.|.|:| ..|:....|.:|:.|:..|||:|||.|.:..:.|...
 Frog   318 WMGFFLAKNKSLQAQCFAEQKAVCGED-LPPLNYDQLKDLQALDRCIKETLRLRPPIMTMMRMAR 381

  Fly   394 QDTVLDGKLIPADSNVII--LIYHAQRDP-DYFPDPEKFIPDRFSMERKGEISPFAYTPFSAGPR 455
            ....:.|..||....|.:  .:.|..||. |...|   |.|||:..:.......|||.||.||..
 Frog   382 TPQSVAGYNIPPGHQVCVSPTVNHRLRDTWDKNTD---FNPDRYLHDNPAAGEKFAYVPFGAGRH 443

  Fly   456 NCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNVILRSTTGINCGLKP 507
            .|||:.||.:::|:..|.|:|.:| ..|.:...|.:|.    ||.|:....|
 Frog   444 RCIGENFAYVQIKTIWSTMLRMYE-FELVDGYFPTINY----TTMIHTPNNP 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	108/442 (24%)
cyp51a1	NP_001016194.1	CYP51-like	84..495	CDD:410668	109/453 (24%)