Protein Alignment Cyp4d14 and cyp26a1

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_012822016.1
• Gene: cyp26a1 / 548901
• XenbaseID: XB-GENE-855583
• Length: 492
• Species: Xenopus tropicalis
• Alignment Length: 499
• Identity: 124/499 - (24%)
• Similarity: 216/499 - (43%)
• Gaps: 80/499 - (16%)

  Fly     8 ILLATALAWD-YMRKRRHNKMYAEAGIRGP-----KSYPLVGNAPLLINESPKSKSSIFDMQFRL 66
            :||..|..|: |...|:      :|..|.|     ...|..|....::.:..|    ...::.|
 Frog    20 LLLTAAKLWEVYCLSRK------DASCRNPLPPGTMGLPFFGETLQMVLQRRK----FLQVKRR- 73

  Fly    67 IAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNW-------LGDGLLI--- 121
              ::|:..||.:.|........::.:..|:..:..:       :.|:|       ||.|.|.
 Frog    74 --KYGRIYKTHLFGSPTVRVTGAENVRQILLGEHKL-------VSVHWPASVRTILGAGCLSNLH 129

  Fly   122 -SQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDII 185
             |:.|   ..:|:|..||..:.|.::|.:.:::....| .|:.::|  :.:.::|........|.
 Frog   130 DSEHK---YTKKVIMQAFSREALANYVPLMEEELRRSV-NLWLQSD--SCVLVYPAIKRLMFRIA 188

  Fly   186 AETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDKLNDAVKNMHD 250
            ....:|      ..||....:...|    |.|.|....:.| |::.:..|  ...|...::..:.
 Frog   189 MRLLLG------CDPQRLGREQEET----LLEAFEEMTRNL-FSLPIDVP--FSGLYRGLRARNI 240

  Fly   251 FTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTIDGAPLSNDDIREEVDTF 315
            ....:....:|.||:. .||...||..|          |:|   .|...|.|::...::|.....
 Frog   241 IHAQIEENIKEKLQRE-PDGQCRDALQL----------LID---HSRRTGEPVNLQALKESATEL 291

  Fly   316 MFEGHDTTTSSIAFTCYLLARHPEVQARVFQEV--RDVIGD--DKSAPVTMKLLGELKYLECVIK 376
            :|.||.||.|:.......||.|.:|..:|.:|:  :.::.:  ::...:::::|.:|||..||||
 Frog   292 LFGGHGTTASAATSLTTFLALHKDVLEKVRKELESQGLLSNKPEEKKELSIEVLQQLKYTSCVIK 356

  Fly   377 ESLRLFPSVPIIG--RYISQDTVLDGKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMERK 439
            |:|||.|  |:.|  |...:..||:|..||...|||..|.....:.:.|||.::|.||||.....
 Frog   357 ETLRLSP--PVAGGFRVALKTFVLNGYQIPKGWNVIYSIADTHGEAELFPDKDEFNPDRFLTPLP 419

  Fly   440 GEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRH--FELL 481
            |:.|.|.:.||..|.|.|:|::||.:.:|..|.::.|:  :|||
 Frog   420 GDSSRFGFIPFGGGVRCCVGKEFAKILLKVFIVELCRNCDWELL 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	111/430 (26%)
cyp26a1	XP_012822016.1	cytochrome_P450	55..485	CDD:477761	114/458 (25%)