Protein Alignment Cyp4d14 and Cyp12a4

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 477
• Identity: 110/477 - (23%)
• Similarity: 204/477 - (42%)
• Gaps: 102/477 - (21%)

  Fly    41 LVGNAPLLINESPKSKSSIFDMQFRLIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQKN 105
            ::||.|.|...:|:.    |::.||     .:.:.....|.           ..::..::..:|:
  Fly    94 IMGNPPFLSTHNPQD----FEVVFR-----NEGVWPNRPGN-----------YTLLYHREEYRKD 138

  Fly   106 NLYSLLVNWLGDGLLISQGKKWFRRRKIITPA-FHFKILEDFVEVFDQQSATMVQKLYDRADGKT 169
            ....::      |::.:|||.|...|.::.|. ...|.:..:.:...|.:...||::.:..|..|
  Fly   139 FYQGVM------GVIPTQGKPWGDFRTVVNPVLMQPKNVRLYYKKMSQVNQEFVQRILELRDPDT 197

  Fly   170 V---------INMFPVACLCAMDIIA-ETAMGVKINAQLQPQ----FTYVQSVTTASAMLAERFM 220
            :         ||.:   .|.::.::| :..:|:..|:..:.:    |.|:......|
  Fly   198 LEAPDDFIDTINRW---TLESVSVVALDKQLGLLKNSNKESEALKLFHYLDEFFIVS-------- 251

  Fly   221 NPLQRLDFTMK------LFYPKLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDADAALLN 279
                 :|..||      :..|| |.:|..|:..:.:.|.:.:.|..|.|.|...:|
  Fly   252 -----IDLEMKPSPWRYIKTPK-LKRLMRALDGIQEVTLAYVDEAIERLDKEAKEG--------- 301

  Fly   280 DVGQKRRMALLDVLLKSTIDGAPLSNDDIREEVDTFM-----FEGHDTTTSSIAFTCYLLARHPE 339
            .|..:...::|:.|||            :..:|.|.|     ..|.|||:|:.......||::||
  Fly   302 VVRPENEQSVLEKLLK------------VDRKVATVMAMDMLMAGVDTTSSTFTALLLCLAKNPE 354

  Fly   340 VQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIP 404
            .|||:.:||..|: .:|::..|...:..:.||...||||.||.|.:....|.:::|.||.|..:|
  Fly   355 KQARLREEVMKVL-PNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVLARDAVLSGYRVP 418

  Fly   405 ADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMERKGEIS-----------PFAYTPFSAGPRNCI 458
            |.:.|.|:..:|....:|||...:|:|:|:....|...|           ||.:.||..|||.|:
  Fly   419 AGTYVNIVPLNALTRDEYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFVFLPFGFGPRMCV 483

  Fly   459 GQKFAMLEMKSTISKMVRHFEL 480
            |::...:|::...::::|:|.:
  Fly   484 GKRIVEMELELGTARLIRNFNV 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	102/447 (23%)
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	110/477 (23%)