Protein Alignment Cyp4d14 and CYP4F3

DIOPT Version :9

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 156/405 - (38%)
• Similarity: 229/405 - (56%)
• Gaps: 16/405 - (3%)

  Fly   108 YSLLVNWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRA-DGKTVI 171
            ||.|..|||||||:|.|:||.|.|:::||||||.||:.::::|::....|..|....| :|...:
Human   125 YSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQLLASEGSARL 189

  Fly   172 NMFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFY-- 234
            :||....|..:|.:.:.......:.|.:|. .|:.::...||::.:|....|..:||   |:|
Human   190 DMFEHISLMTLDSLQKCVFSFDSHCQEKPS-EYIAAILELSALVTKRHQQILLYIDF---LYYLT 250

  Fly   235 PKLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKS-TI 298
            |. ..:...|.:.:||||::||.|||..|.....|.      .|....:.:.:..:||||.| ..
Human   251 PD-GQRFRRACRLVHDFTDAVIQERRRTLPSQGVDD------FLQAKAKSKTLDFIDVLLLSKDE 308

  Fly   299 DGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMK 363
            ||..||::|||.|.|||||||||||.|.:::..|.||:|||.|.|..|||::::.|.:...:...
Human   309 DGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWD 373

  Fly   364 LLGELKYLECVIKESLRLFPSVPIIGRYISQDTVL-DGKLIPADSNVIILIYHAQRDPDYFPDPE 427
            .|.:|.:|...|||||||.|.||.:.|..:||.|| ||::||.....:|.::....:|..:||||
Human   374 DLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPE 438

  Fly   428 KFIPDRFSMERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLN 492
            .:.|.||..:...|.||.|:.||||||||||||.|||.|||..:...:..|.:||...|.:....
Human   439 VYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPE 503

  Fly   493 VILRSTTGINCGLKP 507
            ::||:..|:...::|
Human   504 LVLRAEGGLWLRVEP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	152/385 (39%)
CYP4F3	NP_000887.2	p450	52..515	CDD:365848	155/400 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154790
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750