Protein Alignment Cyp4d14 and Cyp4e2

DIOPT Version :9

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001286196.1
• Gene: Cyp4e2 / 35822
• FlyBaseID: FBgn0014469
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 546
• Identity: 205/546 - (37%)
• Similarity: 305/546 - (55%)
• Gaps: 65/546 - (11%)

  Fly     1 MYLELFAILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKSKSSIFDMQFR 65
            ::|.|..:|:|......:.|:|..||      ..||:..||:|||    ::..|:.|.|.|..|.
  Fly     7 IFLALPLLLVAYLELSTFRRRRVLNK------FNGPRGLPLMGNA----HQMGKNPSEILDTVFS 61

  Fly    66 LIAEFGKNIKTQMLGE-SGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDGLLISQGKKWFR 129
            ...::||:.....:|. |..:...||.:|.|:|||..|.|:::|.|...|||.|||.|.|.||.:
  Fly    62 WWHQYGKDNFVFWIGTYSNVLVTSSKYLEFILSSQTLITKSDIYQLTHPWLGLGLLTSTGSKWHK 126

  Fly   130 RRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAETAMGVKI 194
            .||:|||||||.||:||.||.::.|...::.|...|.|..:.:....|....:|:|.:|||||.|
  Fly   127 HRKMITPAFHFNILQDFHEVMNENSTKFIKHLKTVAAGDNIFDFQEQAHYLTLDVICDTAMGVSI 191

  Fly   195 NAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLF--YPKLLDKLNDAVKNMHDFTNSVIT 257
            ||......:.||:.......:..|..:||:|.:...:|.  ||    ..:..:|.:.||||.:|.
  Fly   192 NAMENRSSSIVQAFKDMCYNINMRAFHPLKRNELLYRLAPDYP----AYSRTLKTLQDFTNEIIA 252

  Fly   258 ERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTIDGAPLSNDDIREEVDTFMFEGHDT 322
            :|.|      |....|.:....|...:::||.||.||.|||||.||::.::.|||.|||||||||
  Fly   253 KRIE------AHKSGAVSTNAGDEFTRKKMAFLDTLLSSTIDGRPLNSKELYEEVSTFMFEGHDT 311

  Fly   323 TTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDK-SAPVTMKLLGELKYLECVIKESLRLFPSVP 386
            |||.::|..|||:||.:.|.::|:|.|:|:|:.: ....|.:.:.::|||:..|||:.|::||||
  Fly   312 TTSGVSFAVYLLSRHQDEQRKLFKEQREVMGNSELGRDATFQEISQMKYLDLFIKEAQRVYPSVP 376

  Fly   387 IIGRYISQDTVLDGKLIPADS----NVIILIYHAQRDPDYFPDPEKFIPDRFSMERKGEISPFAY 447
            .|||:..:|.|:||.|:|..:    .:::|.|:.:    .|.||.||.|:||.:|:.|   ||.|
  Fly   377 FIGRFTEKDYVIDGDLVPKGTTLNLGLVMLGYNEK----VFKDPHKFRPERFELEKPG---PFEY 434

  Fly   448 TPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEV------------------------- 487
            .|||||||||||||||:||:|:.:||::|:||:||..:|:
  Fly   435 VPFSAGPRNCIGQKFALLEIKTVVSKIIRNFEVLPALDELVSKDGYISTTIGLPDAERKKRDPYR 499

  Fly   488 ---QPVLNVI--LRSTTGINCGLKPR 508
               .|:|:.:  |:|..|:...||.|
  Fly   500 HKYDPILSAVLTLKSENGLYIRLKER 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	189/490 (39%)
Cyp4e2	NP_001286196.1	p450	35..469	CDD:278495	186/454 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449034
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	1	0.950	-	0	Normalized mean entropy	S4382
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	11	10.850