Protein Alignment Cyp4d14 and Cyp4e3

DIOPT Version :9

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_523527.1
• Gene: Cyp4e3 / 34291
• FlyBaseID: FBgn0015035
• Length: 526
• Species: Drosophila melanogaster
• Alignment Length: 550
• Identity: 204/550 - (37%)
• Similarity: 307/550 - (55%)
• Gaps: 68/550 - (12%)

  Fly     1 MYLELFAILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKSKSSIFDMQFR 65
            |:|.:.|:|:...:...|..::...:........||...|::|||..:.....:..|:.||..:
  Fly     1 MWLAVLALLVLPLITLVYFERKASQRRQLLKEFNGPTPVPILGNANRIGKNPAEILSTFFDWWY- 64

  Fly    66 LIAEFGKNIKTQMLG-ESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDGLLISQGKKWFR 129
               ::||:.....:| .|..:..:.|.:|.|::|||.|||:.:|.||..|||.|||.|.|.||.:
  Fly    65 ---DYGKDNFLFWIGYSSHIVMTNPKQLEYILNSQQLIQKSTIYDLLHPWLGHGLLTSFGSKWHK 126

  Fly   130 RRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAETAMGVKI 194
            .||:|||:|||.||:||.||.::.||..:.:|...:.|.|:|:....|....:|:|.:|||||.|
  Fly   127 HRKMITPSFHFNILQDFHEVMNENSAKFMTQLKKASAGDTIIDFQEHANYLTLDVICDTAMGVPI 191

  Fly   195 NAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKL-----FYPKLLDKLNDAVKNMHDFTNS 254
            ||..|...:.||:.......:..|..:|.:|.:....|     .|.|.|       |.:.|||..
  Fly   192 NAMEQRDSSIVQAFRDMCYNINMRAFHPFKRSNRVFSLTPEFSAYQKTL-------KTLQDFTYD 249

  Fly   255 VITERRELLQKAIADGG---DADAALLNDVGQKRRMALLDVLLKSTIDGAPLSNDDIREEVDTFM 316
            :|.:|...||    :||   |.|.:|     .:::||.||.||.|||||.||:..:|.|||.|||
  Fly   250 IIEKRVYALQ----NGGSKEDHDPSL-----PRKKMAFLDTLLSSTIDGRPLTRQEIYEEVSTFM 305

  Fly   317 FEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRL 381
            |||||||||.::|:.|||:|||:||.::::|..:|:|.|.:..|:.:.:.::|||:..|||:.|:
  Fly   306 FEGHDTTTSGVSFSVYLLSRHPDVQRKLYREQCEVMGHDMNRSVSFQEIAKMKYLDLFIKEAQRV 370

  Fly   382 FPSVPIIGRYISQDTVLDGKLIPADSNV---IILIYHAQRDPDYFPDPEKFIPDRFSMERKGEIS 443
            :||||.||||..:|..::|.::|..:.:   :||:.:..|   .|.||..|.|:||..|:.   :
  Fly   371 YPSVPFIGRYCDKDYDINGSIVPKGTTLNLALILLGYNDR---IFKDPHHFRPERFEEEKP---A 429

  Fly   444 PFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEV--------------------- 487
            ||.|.|||||||||||||||:||:|:.|||:||.||:||..:|:
  Fly   430 PFEYLPFSAGPRNCIGQKFALLELKTVISKVVRSFEVLPAVDELVSTDGRLNTYLGLAPDEKLKR 494

  Fly   488 -------QPVLNVI--LRSTTGINCGLKPR 508
                   .|:|:.:  |:|..|::..|:.|
  Fly   495 EAGRHKYDPILSAVLTLKSDNGLHLRLRER 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	192/494 (39%)
Cyp4e3	NP_523527.1	p450	35..468	CDD:278495	189/458 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449022
Domainoid	1	1.000	101	1.000	Domainoid score	I1781
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	1	0.950	-	0	Normalized mean entropy	S4382
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D10482at33392
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
	11	10.850