Protein Alignment Cyp4d14 and Cyp4f4

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_775146.1
• Gene: Cyp4f4 / 286904
• RGDID: 708363
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 179/520 - (34%)
• Similarity: 271/520 - (52%)
• Gaps: 55/520 - (10%)

  Fly    32 GIRGPKSYP-----LVGNAPLLINESPKSKSSIFDMQFRLIAEF--------------------- 70
            |:|...|.|     |:|.:.||:.  ..:::.||...::.:.:|
  Rat    10 GLRLETSLPWLLLLLIGASWLLVR--VLTQTYIFYRTYQHLCDFPQPPKWNWFLGHLGMITPTEQ 72

  Fly    71 GKNIKTQMLG--ESGFMT-----------ADSKMIEAIMSSQQTIQKNNL--YSLLVNWLGDGLL 120
            |....|:::.  ..||||           ....:|.:::|:..::....:  ||.|..|||||||
  Rat    73 GLKQVTKLVATYPQGFMTWLGPILPIITLCHPDVIRSVLSASASVALKEVIFYSFLKPWLGDGLL 137

  Fly   121 ISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTV-INMFPVACLCAMDI 184
            :|.|.||...|:::||||||.||:.:|::|:..:..|..|..|.|.|.:. ::||....|..:|.
  Rat   138 LSDGDKWSCHRRMLTPAFHFNILKPYVKIFNDSTNIMHAKWQDLASGGSARLDMFKNISLMTLDS 202

  Fly   185 IAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDKLNDAVKNMH 249
            :.:.......|.|.:|. .|:.::...||::|:|:...|...|...:|.:..  .:.:.|.|.:|
  Rat   203 LQKCVFSFDSNCQEKPS-EYISAILELSALVAKRYQQLLLHTDSLYQLTHNG--RRFHKACKLVH 264

  Fly   250 DFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDV-LLKSTIDGAPLSNDDIREEVD 313
            :||::||..||..|.....|.      :|....:.:.:..:|| ||....||..||::|||.|.|
  Rat   265 NFTDAVIQGRRRALPSQHEDD------ILKAKARSKTLDFIDVLLLTKDEDGKELSDEDIRAEAD 323

  Fly   314 TFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKES 378
            ||||||||||.|.:::..|.||||||.|.|..||||:::.|.:|..:....|.:|.:|...||||
  Rat   324 TFMFEGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDRESTEIEWDDLAQLPFLTMCIKES 388

  Fly   379 LRLFPSVPIIGRYISQDTVL-DGKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMERKGEI 442
            |||.|.|.:|.|..:||.|| ||::||.....||.|:....:|..:||||.:.|.||..|...:.
  Rat   389 LRLHPPVTVISRRCTQDIVLPDGRVIPKGVICIINIFATHHNPTVWPDPEVYDPFRFDPENIKDR 453

  Fly   443 SPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNVILRSTTGINCGLKP 507
            ||.|:.||||||||||||.|||.|||..::..:..|.:||..:|.:....:|||:..|:...::|
  Rat   454 SPLAFIPFSAGPRNCIGQTFAMNEMKVALALTLLRFRVLPDDKEPRRKPELILRAEGGLWLRVEP 518

  Fly   508  507
              Rat   519  518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	167/449 (37%)
Cyp4f4	NP_775146.1	CYP4F	74..515	CDD:410772	166/449 (37%)