Protein Alignment Cyp4d14 and Cyp19a1

DIOPT Version :9

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_058781.2
• Gene: Cyp19a1 / 25147
• RGDID: 2457
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 107/499 - (21%)
• Similarity: 205/499 - (41%)
• Gaps: 112/499 - (22%)

  Fly    24 HNKMYAE---AGIRGPKSYPLVGNAPLLINESPKSKSSIFDMQF-RLIAEFGKNIKTQMLG--ES 82
            :||||.|   ..|.|.::        |:|:   ||.|.:..|:. ..|:.||.....|.:|  |:
  Rat    77 YNKMYGEFMRVWISGEET--------LIIS---KSSSMVHVMKHSNYISRFGSKRGLQCIGMHEN 130

  Fly    83 GFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFV 147
            |.:..::.      |..:|::...:.:|    .|.||:                    :::|..|
  Rat   131 GIIFNNNP------SLWRTVRPFFMKAL----TGPGLI--------------------RMVEVCV 165

  Fly   148 EVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTAS 212
            |...|.    :.:|.|..|....:::..:.....:|......:|:.::     :.:.|:.:
  Rat   166 ESIKQH----LDRLGDVTDNSGYVDVVTLMRHIMLDTSNTLFLGIPLD-----ESSIVKKI---- 217

  Fly   213 AMLAERFMNPLQRLDFTMKLFY--PKLLDKLNDAVKNMHDFTNSVITERRELLQKA--IADGGDA 273
                :.:.|..|.|.....:|:  ..|..|...:||::.|....::.::|:.:..|  :.|..|.
  Rat   218 ----QGYFNAWQALLIKPNIFFKISWLYRKYERSVKDLKDEIEILVEKKRQKVSSAEKLEDCMDF 278

  Fly   274 DAALLNDVGQKRRMALLDVLLKSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHP 338
            ...|   :..:||              ..|:.:::.:.:...:....||.:.::.....|:|.:|
  Rat   279 ATDL---IFAERR--------------GDLTKENVNQCILEMLIAAPDTMSVTLYVMLLLIAEYP 326

  Fly   339 EVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLI 403
            ||:..:.:|:..|:||   ..:.:..:..||.:|..|.||||..|.|.::.|...:|.|:||..:
  Rat   327 EVETAILKEIHTVVGD---RDIRIGDVQNLKVVENFINESLRYQPVVDLVMRRALEDDVIDGYPV 388

  Fly   404 PADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMERKGEISPFAY-TPFSAGPRNCIGQKFAMLEM 467
            ...:|:|:.|....| .:|||.|.:|..:.|...     .|:.| .||..|||:|.|:..||:.|
  Rat   389 KKGTNIILNIGRMHR-LEYFPKPNEFTLENFEKN-----VPYRYFQPFGFGPRSCAGKYIAMVMM 447

  Fly   468 KSTISKMVRHFELLPLG-----------------EEVQPVLNVI 494
            |..:..:::.|.:..|.                 :|..|::.:|
  Rat   448 KVVLVTLLKRFHVKTLQKRCIENMPKNNDLSLHLDEDSPIVEII 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	p450	34..489	CDD:278495	99/479 (21%)
Cyp19a1	NP_058781.2	CYP19A1	72..485	CDD:410709	105/491 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348678
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950