Protein Alignment Cyp4d14 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_058695.2
• Gene: Cyp4b1 / 24307
• RGDID: 2480
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 166/521 - (31%)
• Similarity: 252/521 - (48%)
• Gaps: 59/521 - (11%)

  Fly     3 LELFAILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKSKSSIFDMQFRLI 67
            |:||::||           ||.....|.....||.::.|.|:|..:.......|...:..||...
  Rat    27 LKLFSLLL-----------RRQKLARAMDSFPGPPTHWLFGHALEIQKLGSLDKVVSWAQQFPHA 80

  Fly    68 AE--FGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDGLLISQGKKWFRR 130
            ..  ||:.:        ||:..........:.|:...:..::|...:.|:|.|||:..|.|||:.
  Rat    81 HPLWFGQFV--------GFLNIYEPDYAKAVYSRGDPKAADVYDFFLQWIGKGLLVLDGPKWFQH 137

  Fly   131 RKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAETAMGVKIN 195
            ||::||.||:.:|:.:|.:|.:.:..|:.|...:|......::|......|:|.:.:...|...:
  Rat   138 RKLLTPGFHYDVLKPYVAIFAESTRMMLDKWEKKASENKSFDIFCDVGHMALDTLMKCTFGKGDS 202

  Fly   196 AQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKL------FYPKLLDKLNDAVKNMHDFTNS 254
            .......:|..:|:..:.::.:|..:.....||...|      |.        .|.|..||.|:.
  Rat   203 GLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLTPHGRRFL--------RACKIAHDHTDE 259

  Fly   255 VITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTID-GAPLSNDDIREEVDTFMFE 318
            ||.:|:..||         |......:.|:|.:..||:||....: |..||:.::|.||||||||
  Rat   260 VIRQRKAALQ---------DEKERKKIQQRRHLDFLDILLGVRDESGIKLSDAELRAEVDTFMFE 315

  Fly   319 GHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFP 383
            |||||||.|::..|.:|.:||.|....:|||.::||..|  .....|.::.||...:||..||:|
  Rat   316 GHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQDS--FQWDDLAKMTYLTMCMKECFRLYP 378

  Fly   384 SVPIIGRYISQD-TVLDGKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMERKGEISPFAY 447
            .||.:.|.:::. |.:||:.:||.|.:.:.||...|:...:||||.|.|.|||.|......|||:
  Rat   379 PVPQVYRQLNKPVTFVDGRSLPAGSLISLHIYALHRNSTVWPDPEVFDPLRFSPENAAGRHPFAF 443

  Fly   448 TPFSAGPRNCIGQKFAMLEMKSTISKMVRHFEL------LPLGEEVQPVLNVILRSTTGINCGLK 506
            .||||||||||||:|||.|||...:..:..||.      :|:     .|..:||||..||:..||
  Rat   444 MPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFSLDPSKMPI-----KVPQLILRSKNGIHLYLK 503

  Fly   507 P 507
            |
  Rat   504 P 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	146/445 (33%)
Cyp4b1	NP_058695.2	CYP4B-like	67..501	CDD:410771	150/465 (32%)