Protein Alignment Cyp4d14 and CYP4Z1

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_835235.1
• Gene: CYP4Z1 / 199974
• HGNCID: 20583
• Length: 505
• Species: Homo sapiens
• Alignment Length: 400
• Identity: 137/400 - (34%)
• Similarity: 213/400 - (53%)
• Gaps: 20/400 - (5%)

  Fly   108 YSLLVNWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVIN 172
            :.:|.:|:|.||:...|.||.:.|:|:.|.|:..||:.|:.:..:....|:.|..:.....:.:.
Human   114 HKILESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLE 178

  Fly   173 MFPVACLCAMDIIAETAMGVKINAQLQPQF-TYVQSVTTASAMLAERFMNPLQRLDFTMKL-FYP 235
            :|....|..:|.|.:.|...:.:.||.... :|:::|...|.:..:|..|.|...|...|. ...
Human   179 LFQHVSLMTLDSIMKCAFSHQGSIQLDSTLDSYLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQG 243

  Fly   236 KLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTIDG 300
            ::..|.|   :.:|.||..||.:|:|.|:.          .|..|..||||...||:||.:..:.
Human   244 QIFSKFN---QELHQFTEKVIQDRKESLKD----------KLKQDTTQKRRWDFLDILLSAKSEN 295

  Fly   301 A-PLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKL 364
            . ..|..|::.||.||||.|||||:|:|::..|.||::||.|.|...|:|:::||..|  :|.:.
Human   296 TKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSS--ITWEH 358

  Fly   365 LGELKYLECVIKESLRLFPSVPIIGRYISQD-TVLDGKLIPADSNVIILIYHAQRDPDYFPDPEK 428
            |.::.|....|||.|||:..|..|.|.:.:. |..||:.:||...|.|.|:....:|.::.||:.
Human   359 LSQMPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQV 423

  Fly   429 FIPDRFSMERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLP-LGEEVQPVLN 492
            |.|.|||.|...:|.|:|:.|||||.||||||.||::|.|..::..:..|:|.| .....|||..
Human   424 FNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPVRQ 488

  Fly   493 VILRSTTGIN 502
            |:|:|..||:
Human   489 VVLKSKNGIH 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	137/399 (34%)
CYP4Z1	NP_835235.1	CYP4B-like	66..500	CDD:410771	137/399 (34%)