Protein Alignment Cyp4d14 and cyp-13A1

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001369869.1
• Gene: cyp-13A1 / 188361
• WormBaseID: WBGene00011677
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 142/568 - (25%)
• Similarity: 230/568 - (40%)
• Gaps: 148/568 - (26%)

  Fly    16 WDYMRKRRHNKMYAEAGIRGPKSYPLVG---NAPLLINESPKSKSSIFDMQFR-LIAEFGK---- 72
            |.:.|:|         |:.||..:|::|   |:  |.|..|      |.:|.| ...:|||
 Worm    24 WTFWRRR---------GVVGPMGFPVLGVFLNS--LDNNFP------FPLQCREWTKKFGKIYGF 71

  Fly    73 ---NIKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWL-GD-------GLLISQGKK 126
               .:||.::       :|.:::..:..:|.    :|.|....|.: ||       .|..:||.:
 Worm    72 TEGTLKTLVI-------SDPELVHEVFVTQY----DNFYGRKRNPIQGDSEKEKRTNLFAAQGFR 125

  Fly   127 WFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAETAMG 191
            |.|.|.|.:|.|....|....:..:..:..:::.:..::.|...|:|........:|:|...|||
 Worm   126 WKRLRAISSPTFSNSSLRKLYQTVEDSALELLRHIEKQSAGGKQIDMLKFYQEFTLDVIGRIAMG 190

  Fly   192 VKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLF-------------YPKLL----- 238
                             .|.|.|    |.||:  :....|||             :|..|
 Worm   191 -----------------QTDSQM----FKNPI--MPIVSKLFQGNFAKLFLIGGIFPTFLVEIIR 232

  Fly   239 ------------DKLN----DAVKNMHDFTNSVITERRELLQKAIADGGDAD------AALLNDV 281
                        .|:|    ||:.|.       |.:|.|..:..|..|..||      .|...||
 Worm   233 QILLKNLKVGSFRKINEITLDAIHNR-------IKQREEDQKNGIEIGEPADFIDLFLDAKAEDV 290

  Fly   282 ---GQKRRMALLDVLLKSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQAR 343
               |:...    |....:|.....|:.::|..:...|:..|.|||..|:::..||||.|||:|.:
 Worm   291 EHFGENNG----DFSKSTTYTNRQLTTEEIVGQCTVFLIAGFDTTALSLSYATYLLATHPEIQKK 351

  Fly   344 VFQEVRDVIGDDKSAP---VTMKLLGELKYLECVIKESLRLFPSVPIIGRYIS-----QDTVLDG 400
            :.:||      ::..|   ||:..|.:|||:|||.||:|||:|    :|.:.:     ::|.|..
 Worm   352 LQEEV------NRECPNPEVTIDQLSKLKYMECVFKEALRLYP----LGAFANSRRCMRNTKLGN 406

  Fly   401 KLIPADSNVIILIYHAQRDPDYF-PDPEKFIPDRFSMERKGEI-SPFAYTPFSAGPRNCIGQKFA 463
            ..:...:.:.:..:....||:.: .|.|.|.|:|:......:| ....|.||..|||.|||.:.|
 Worm   407 MKVEVGTMIQVDTWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQKSGYIPFGLGPRQCIGMRLA 471

  Fly   464 MLEMKSTISKMVRHFELLPLGEEVQPVLNVILRSTT---GINCGLKPR 508
            .:|.|..:..::|.| ....|.:.:..|.:|.|:||   .:...|.||
 Worm   472 YMEEKILLVHILRKF-TFETGAKTEIPLKLIGRATTQPESVWMHLNPR 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	123/502 (25%)
cyp-13A1	NP_001369869.1	CYP3A-like	64..510	CDD:410678	124/501 (25%)