Protein Alignment Cyp4d14 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 536
• Identity: 137/536 - (25%)
• Similarity: 233/536 - (43%)
• Gaps: 86/536 - (16%)

  Fly    16 WDY-MRKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKSKSSIFDMQFRLIAEFGKNIKTQML 79
            |.| |||          |::||:..|.||...:|:.........:.:...:....:|....||..
 Worm    25 WTYWMRK----------GVKGPRGRPFVGVLDVLLEHETPGLIKLGEWTKKYGKVYGYTDGTQRT 79

  Fly    80 GESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNWLGDG--------LLISQGKKWFRRRKIITP 136
                .:.||..|:..|...    |.:|.|...:|.:...        ||.:||.:|.|.|.|.:.
 Worm    80 ----LVVADPAMVHEIFVK----QFDNFYGRKLNPIQGNPEKEQRVHLLAAQGYRWKRLRTISSQ 136

  Fly   137 AFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAETAMGVKINAQLQ-P 200
            :|....|:......:..:..:::.:..:..|...|:|........||:|...|||...:...: |
 Worm   137 SFSNASLKKMKRTVEDSALELLRHIEKQTAGGEQIDMLRFYQEYTMDVIGRFAMGQTDSMMFKNP 201

  Fly   201 QFTYVQSVTTAS---AMLAERFMNPLQRL--DFTMKLFYPKLLDKLNDAVK---NMHDFTNSVIT 257
            ....|:.:...|   .||..:...|:.:.  |.|.|  :|::     .|.|   .|.|...:.|.
 Worm   202 IVNVVREIFCGSRKNLMLICQVFPPIGQFIRDLTFK--FPRI-----PAFKLYSIMQDVVAARIA 259

  Fly   258 ERR--------------ELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTIDGAPLSNDDI 308
            :|.              :|...|.:|..|..|....|..::.        ||.|.:   ||.|::
 Worm   260 QREREKGAESGEPQDFIDLFLDARSDDVDFSAEAREDFSKRN--------LKITKE---LSADEV 313

  Fly   309 REEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLEC 373
            ..:...|:..|.|||..|:::..||||.:|::|.:|.:|:....|   ::.|..:.||.|||::|
 Worm   314 VGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAREFG---TSEVEFEKLGRLKYMDC 375

  Fly   374 VIKESLRLFPSVPII-GRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYF-PDPEKFIPDRFS- 435
            ||||:|||:|...|. .|...:.|.::|..|.|...|.:..:....||:.: .|.::|.|:|:|
 Worm   376 VIKEALRLYPLASISNSRKCMKTTTVNGVKIEAGVYVQMDTWSLHYDPELWGEDVKEFKPERWST 440

  Fly   436 ---MERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNVILRS 497
               :|.||     ||.||..|||.|||.:.|::|.|..::.::::: ....|.:.:..|.::..:
 Worm   441 DEPLEHKG-----AYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNY-TFETGNKTRIPLKLVGSA 499

  Fly   498 TTG---INCGLKPRVY 510
            ||.   :...|:||::
 Worm   500 TTSPEDVFVHLRPRIW 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	122/471 (26%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	122/477 (26%)