Protein Alignment Cyp4d14 and cyp-13A3

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_496110.1
• Gene: cyp-13A3 / 188359
• WormBaseID: WBGene00011675
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 592
• Identity: 153/592 - (25%)
• Similarity: 238/592 - (40%)
• Gaps: 168/592 - (28%)

  Fly     7 AILLATAL----------AWDY-MRKRRHNKMYAEAGIRGPKSYPLVG--NA------PLLINES 52
            :||:|.||          .|.: |||          ||:||:..|..|  ||      |.::...
 Worm     4 SILIAIALFIGVFTYYLWIWSFWMRK----------GIKGPRGLPFFGIINAFQSYEKPWILRLG 58

  Fly    53 PKSKSSIFDMQFRLIAEFGKNIKTQMLG-----ESGFMTADSKMIEAIMSSQQTIQKNNLYSLLV 112
            ..:|            |:|     .|.|     |...:.:|.:.:..:...    |.:|.|:...
 Worm    59 DWTK------------EYG-----PMYGFTDGVEKTLVVSDPEFVHEVFVK----QFDNFYARKQ 102

  Fly   113 NWL-GD-------GLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKT 169
            |.| ||       .|:.|||.:|.|.|.:.:|.|..|.|.......::..|.|::.|.....|..
 Worm   103 NPLQGDPDKDPRIHLVTSQGHRWKRLRTLASPTFSNKSLRKIFSTVEESVAEMMRHLEKGTAGGK 167

  Fly   170 VINMFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFY 234
            .|::........||||.:.|||                  .:.:|:   |.||
 Worm   168 TIDILEYYQEFTMDIIGKIAMG------------------QSGSMM---FENP------------ 199

  Fly   235 PKLLDKLNDAVKNMH-----------DFTNSV-------------ITERRELLQKAIADGGDADA 275
              .|||:. |:.|..           .||.|:             :|.....|:.|:....:..|
 Worm   200 --WLDKIR-AIFNTRGNIIFIICGIVPFTGSIFRWFFSKVPTAQTVTSLMHTLEIALTKRVEQRA 261

  Fly   276 A-----------------LLNDVGQKRRMALLDVLLKSTIDG----------APLSNDDIREEVD 313
            |                 |..||     .|..|.|...|.:|          ..|:.|:|..::.
 Worm   262 ADEKAGIESSGEPQDFIDLFLDV-----QADTDFLEDETKNGFARSQIVKVDKHLTFDEIIGQLF 321

  Fly   314 TFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAP---VTMKLLGELKYLECVI 375
            .|:..|:|||..|::::.||||||||:|.::.:||      |:..|   ||...|.:|||:||||
 Worm   322 VFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEV------DRECPDPEVTFDQLSKLKYMECVI 380

  Fly   376 KESLRLFPSVPII-GRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYF-PDPEKFIPDRFSMER 438
            ||:|||:|...|: .|...:.|.:.|..|...:||....:....||.:: .:..:|.|:|:....
 Worm   381 KETLRLYPLASIVHNRKCMKSTTVLGMKIEEGTNVQADTWTLHYDPKFWGENANEFKPERWESGD 445

  Fly   439 KGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNVILRST--TGI 501
            :..::..||.||..|||.|||.:.|.:|.|..::::::.:.|....|...|:..|.:.:|  |.:
 Worm   446 EQAVAKGAYLPFGLGPRICIGMRLAYMEEKMLLAQILKKYSLETTFETHIPLKLVGIATTAPTNV 510

  Fly   502 NCGLKPR 508
            :..||||
 Worm   511 HLKLKPR 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	129/502 (26%)
cyp-13A3	NP_496110.1	CYP3A-like	63..509	CDD:410678	129/501 (26%)