Protein Alignment Cyp4d14 and cyp-13A6

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_496113.1
• Gene: cyp-13A6 / 188357
• WormBaseID: WBGene00011673
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 583
• Identity: 137/583 - (23%)
• Similarity: 230/583 - (39%)
• Gaps: 143/583 - (24%)

  Fly     1 MYLELFAILLA----TALAWDYMRKRRHNKMYAEAGIRGPKSYPLVG---------NAPLL---- 48
            :::.|.|:||.    :...|.|         :...||:||:.:|.:|         |.|.|
 Worm     2 IFVLLSAVLLGVFTYSVWIWSY---------FIRKGIKGPRGFPGIGMLIQTIDHENPPFLKYRD 57

  Fly    49 -------------------INESPKSKSSIFDMQFRLIAEFGKNIKTQMLGESGFMTADSKMIEA 94
                               |...|:..:.||..||...  :|:.::                  .
 Worm    58 WTKQYGPVYGFTEGPQQTMIISEPEMVNEIFKKQFDNF--YGRKLR------------------P 102

  Fly    95 IMSSQQTIQKNNLYSLLVNWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMV- 158
            |:...:..::.|::|            :|||:|.|.|.:.:|:|....|.. |....|:..|.:
 Worm   103 IIGDPEKDKRVNIFS------------TQGKRWKRLRTLSSPSFSNNSLRK-VRNSVQECGTEIL 154

  Fly   159 ----QKLYDRADGKTVINMFPVACLCAMDIIAETAMG-VKINAQLQPQFTYVQSVTTAS--AMLA 216
                ||:....|    |:|..|.....:.:|:..|:| .:.|....|....||::...|  ..|.
 Worm   155 WNIEQKVRKNED----IDMLIVYQEYTLGVISRIALGQSESNMFKNPLLPKVQAIFNGSWHVFLI 215

  Fly   217 ERFMNPLQRLDFTMKLFYP-------KLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDAD 274
            .....||..:...|....|       |:.|.:..||:       :.|.:|.:...|.:..|...|
 Worm   216 TGIFPPLAGVFRKMSKMLPASFIPAFKIFDLIEVAVQ-------ARIDQRAKDEIKGVEPGEPQD 273

  Fly   275 ------AALLNDVGQKRRMALLDVLLKSTID-GAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCY 332
                  .|.:.||......|..|....|.:. ...|:.|:|..:...|:..|.|||..|:::..|
 Worm   274 FIDLFLDARVPDVKILSGEANEDFAKSSVVKINKELTFDEIIAQCFVFLAAGFDTTALSLSYATY 338

  Fly   333 LLARHPEVQARVFQEVRDVIGDDKSAP---VTMKLLGELKYLECVIKESLRLFPSVPIIG----- 389
            |||.|||:|.::.:||      |:..|   :....|.:|||||||:||:|||:|    :|
 Worm   339 LLATHPEIQTKLQEEV------DRECPDPEIFFDHLSKLKYLECVMKETLRLYP----LGTTANT 393

  Fly   390 RYISQDTVLDGKLIPADSNVIILIYHAQRDPDYF-PDPEKFIPDRFS------MERKGEISPFAY 447
            |...::|.::|.......|:.:..:....:|..: .|.|.|.|:|:.      :|..|     :|
 Worm   394 RKCMRETTINGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNG-----SY 453

  Fly   448 TPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPV--LNVILRSTTGINCGLKPR 508
            .||.:|||.|||.:.|.:|.|..::::::.:..........||  :..:..|...:...|:||
 Worm   454 IPFGSGPRQCIGMRLAQMEQKILLAQILKEYSFRTTKNTQIPVKLVGKLTLSPESVIVKLEPR 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	113/470 (24%)
cyp-13A6	NP_496113.1	CYP3A-like	61..511	CDD:410678	119/508 (23%)