Protein Alignment Cyp4d14 and cyp-13B2

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_510369.2
• Gene: cyp-13B2 / 187068
• WormBaseID: WBGene00010606
• Length: 511
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 123/574 - (21%)
• Similarity: 224/574 - (39%)
• Gaps: 161/574 - (28%)

  Fly     5 LFAIL--LATALAW--DYMRKRRHNKMYAEAGIRGPKSYPLVGN----------APLLINESPKS 55
            |.||:  :|....|  .|.::|         ||.||...|.:|:          ...:||:..|.
 Worm     7 LVAIIGVVAGYFKWIHSYWKRR---------GIEGPVGLPFIGSFYDLADREKPRGFIINKWTKM 62

  Fly    56 KSSIF---------------DM-QFRLIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQK 104
            ...:|               || |...|.:|          :..:....:.:|...:...|...:
 Worm    63 FGKVFGYYEGVIPVLVVSDLDMLQEMFIKKF----------DCFYARKTTNLIHGNLECSQEEPR 117

  Fly   105 NNLYSLLVNWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKT 169
            .||::            ::|.:|.|.|.:.:|||..|.|:...|..:....:||..:..:.:|:
 Worm   118 VNLFA------------ARGARWKRLRALASPAFSVKALKQIHETMEDSVFSMVDHMSKQVNGE- 169

  Fly   170 VINMFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLF- 233
            ..|:.........|:|:..|||.          ||           :|:|.|  :.:|...|:|
 Worm   170 AFNIHEYYQEFTYDVISRLAMGQ----------TY-----------SEQFNN--EGVDIVKKIFL 211

  Fly   234 -----YPKLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDADAAL------LNDVGQKRR- 286
                 ||..|..:....:|         |.:..........|||....|      ::|..::|.
 Worm   212 RKNRVYPWYLAVMFPGFEN---------TIKNTFFNHEAVRGGDVGKLLKFCETAVHDRLKERAD 267

  Fly   287 --------------MALLDVLLKSTI-DGA-------PLSNDDIREEVDTFMFEGHDTTTSSIAF 329
                          ...||....:.| |.|       .::::|:......|:..|.|||.:::|:
 Worm   268 NVEQGIENPHNDFIDMFLDYYTDTNIEDNAFGIKVEKKVTSEDVIGACFVFLLAGFDTTANTLAY 332

  Fly   330 TCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFP----------- 383
            ..||||:||:...:|..|:..:.   .|..::...:|:|:|::.||:|:||::|
 Worm   333 ASYLLAKHPQEMRKVQDEIDRIC---TSEHISYDDIGKLRYMDAVIREALRMYPVAWFACSRECV 394

  Fly   384 SVPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMERKGEISP---F 445
            ....:|.|..:      |.:..:::|..|.|   .:..:..:..:|:|:|:.     |.||   .
 Worm   395 QATTLGNYYIE------KGVRIEADVRALHY---SEEIWGKNANEFVPERWL-----ESSPRHNM 445

  Fly   446 AYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNVILRSTT 499
            ::.||.||||.|:|.:..:.|.|:.::.::|.|.:| .|.:.:..|::...:||
 Worm   446 SWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRFSIL-AGPKTEKELHLQGCTTT 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	101/478 (21%)
cyp-13B2	NP_510369.2	CYP3A-like	62..505	CDD:410678	107/510 (21%)