Protein Alignment Cyp4d14 and cyp-13B1

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_510233.1
• Gene: cyp-13B1 / 181462
• WormBaseID: WBGene00008519
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 573
• Identity: 135/573 - (23%)
• Similarity: 238/573 - (41%)
• Gaps: 136/573 - (23%)

  Fly     5 LFAILLATALAW-----DYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLIN-ESPKSKSSIFDMQ 63
            :..:|.||...:     .|.|:|         ||.||:..|.:||...|.: ..|:..     :.
 Worm     6 VLVVLFATIAGYFKWIHTYWRRR---------GISGPEGLPFIGNYYDLADVNKPRGY-----LI 56

  Fly    64 FRLIAEFGKNIKTQMLGESGFMTADSKMIEAIM--------SSQQTIQKNNLYSLL--------V 112
            .:...:|||............:.:|..|::.:.        :.:.|   |:::..|        :
 Worm    57 HKWTQKFGKVFGYYEGAVPVLVVSDMDMLQELFLKKFDNFYARKST---NHIHGNLECSKSEPRI 118

  Fly   113 NWLGDGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVA 177
            |     |..|:|.:|.|.|.:.:|.|..|.|:...:|.:..:..||..:....|||. .|:....
 Worm   119 N-----LFTSRGARWKRLRALASPGFSVKALKQVHDVMEDSAINMVDLMAKHEDGKP-FNIHAYF 177

  Fly   178 CLCAMDIIAETAMGVKINAQL--QPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDK 240
            .....|:|:..||| :.|::|  ......|:|:          ||...:.|.:...:.:|    :
 Worm   178 QEFTYDVISRLAMG-QPNSELFNNSGVEIVKSI----------FMRTHRVLPWYFTVLFP----Q 227

  Fly   241 LNDAVKNMHDFTNSVITERRELLQKAIADGGDADAALL-------NDVGQKRRMALL-------- 290
            ....||.|  |.|           .|...|||.:..||       :.:.::...|.|
 Worm   228 FEHLVKRM--FYN-----------HAAVQGGDIEKLLLICKKTVESRIQEREENAKLGFENAEND 279

  Fly   291 --------------DVLLKSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQ 341
                          |:...||:: ..::.:|:......|:..|.|||.:|:|:..||||:|||..
 Worm   280 FIDMFLNYYSEQVEDIEFGSTVE-KKVTAEDVIGACFVFLLAGFDTTANSLAYASYLLAKHPEKM 343

  Fly   342 ARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFP------SVPIIGRYISQDTVLD- 399
            ....:||..|:|.:.   |:...:.:||||:.|::|||||:|      |...:......|..:|
 Worm   344 KLAQEEVDTVVGSEN---VSYDDMTKLKYLDAVVRESLRLYPVAWFACSRECVKPTTLGDIYIDK 405

  Fly   400 GKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMERKGEISP-----FAYTPFSAGPRNCIG 459
            |..|.||    ::..|..:: .:..:.:.|:|:|:       :.|     .::.||.||||.|:|
 Worm   406 GVKIEAD----VMSLHRSKE-IWGENADDFVPERW-------LEPSSRHTMSWIPFGAGPRQCVG 458

  Fly   460 QKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNVILRSTT---GINCGLKPRV 509
            .:..:.|.|:.::.::|.::|: .|.|.:..||::..:||   .:...||||:
 Worm   459 MRLGLSEAKTALAHLLRRYDLV-AGVETEKELNILGCTTTSPEAVTLYLKPRI 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	115/493 (23%)
cyp-13B1	NP_510233.1	CYP3A-like	62..500	CDD:410678	116/491 (24%)