Protein Alignment Cyp4d14 and Cyp51

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_064394.2
• Gene: Cyp51 / 13121
• MGIID: 106040
• Length: 503
• Species: Mus musculus
• Alignment Length: 498
• Identity: 116/498 - (23%)
• Similarity: 207/498 - (41%)
• Gaps: 76/498 - (15%)

  Fly     5 LFAILLATA--LAWDYM-RKRRHNKMYAEAGIRGP----KSYPLVGNAPLLINESPKSKSSIFDM 62
            |..:|:|.|  |:..|: |....:.:...||.:.|    ...|.:|:| :...:||        :
Mouse    27 LSTLLIACAFTLSLVYLFRLAVGHMVQLPAGAKSPPHIYSPIPFLGHA-IAFGKSP--------I 82

  Fly    63 QF--RLIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQ-QTIQKNNLYSLLVN-WLGDGLLISQ 123
            :|  ....::|......|:|::......|.....:.:|: :.:....:|..|.. ..|.|:....
Mouse    83 EFLENAYEKYGPVFSFTMVGKTFTYLLGSDAAALLFNSKNEDLNAEEVYGRLTTPVFGKGVAYDV 147

  Fly   124 GKKWF-RRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCAMDIIAE 187
            ....| .::|||....:....:.:|.:.::::....|...:..:.    |:|.    ...::|..
Mouse   148 PNAIFLEQKKIIKSGLNIAHFKQYVPIIEKEAKEYFQSWGESGER----NVFE----ALSELIIL 204

  Fly   188 TAM----GVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDKLNDAVKNM 248
            ||.    |.:|.:||.      :.|....|.|...|.:....|...:.|...:..|:.:..:||
Mouse   205 TASHCLHGKEIRSQLN------EKVAQLYADLDGGFTHAAWLLPAWLPLPSFRRRDRAHREIKN- 262

  Fly   249 HDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMA------LLDVLLKSTI-DGAPLSND 306
                         :..|||               ||||::      :|..||.||. ||.||:::
Mouse   263 -------------IFYKAI---------------QKRRLSKEPAEDILQTLLDSTYKDGRPLTDE 299

  Fly   307 DIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYL 371
            :|...:...:..|..|::::.|:..:.||:...:|.:.:.|.:.|.|:| ..|:|...|.:|..|
Mouse   300 EISGMLIGLLLAGQHTSSTTSAWMGFFLAKDKPLQEKCYLEQKAVCGED-LPPLTYDQLKDLNLL 363

  Fly   372 ECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFSM 436
            :..|||:|||.|.:..:.|.......:.|..||....|.:.....||..|.:.:...|.|||:..
Mouse   364 DRCIKETLRLRPPIMTMMRMAKTPQTVAGYTIPPGHQVCVSPTVNQRLKDSWAERLDFNPDRYLQ 428

  Fly   437 ERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFE 479
            :.......|||.||.||...|:|:.||.:::|:..|.|:|.:|
Mouse   429 DNPASGEKFAYVPFGAGRHRCVGENFAYVQIKTIWSTMLRLYE 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	100/423 (24%)
Cyp51	NP_064394.2	CYP51-like	88..499	CDD:410668	100/428 (23%)