Protein Alignment Cyp4d14 and Cyp26a1

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_031837.2
• Gene: Cyp26a1 / 13082
• MGIID: 1096359
• Length: 497
• Species: Mus musculus
• Alignment Length: 518
• Identity: 124/518 - (23%)
• Similarity: 213/518 - (41%)
• Gaps: 73/518 - (14%)

  Fly     8 ILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLINESPKSKSSIFDMQFRLIAEFGK 72
            :.||....||.......::..|.....|...:|..|....::.:..|    ...|:.|   ::|.
Mouse    20 LFLAALKLWDLYCVSSRDRSCALPLPPGTMGFPFFGETLQMVLQRRK----FLQMKRR---KYGF 77

  Fly    73 NIKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVNW-------LGDGLLIS-QGKKWFR 129
            ..||.:.|........:..:..|:..:..:       :.|:|       ||.|.|.: ......:
Mouse    78 IYKTHLFGRPTVRVMGADNVRRILLGEHRL-------VSVHWPASVRTILGAGCLSNLHDSSHKQ 135

  Fly   130 RRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFP----VACLCAMDIIAETAM 190
            |:|:|..||..:.|:.:|.|..::.::.:::..  :.|:..:.::|    :....||.|:.....
Mouse   136 RKKVIMQAFSREALQCYVPVIAEEVSSCLEQWL--SCGERGLLVYPEVKRLMFRIAMRILLGCEP 198

  Fly   191 GVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDKLNDAVKN---MHDFT 252
            |.....:.:.|             |.|.|....:.| |::.:..|  ...|...||.   :|...
Mouse   199 GPAGGGEDEQQ-------------LVEAFEEMTRNL-FSLPIDVP--FSGLYRGVKARNLIHARI 247

  Fly   253 NSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTID-GAPLSNDDIREEVDTFM 316
            ...|..:...||....|||..||              |.:|::.:.: |..|....:::.....:
Mouse   248 EENIRAKIRRLQATEPDGGCKDA--------------LQLLIEHSWERGERLDMQALKQSSTELL 298

  Fly   317 FEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRD---VIGDDKSAPVTMKLLGELKYLECVIKES 378
            |.||:||.|:.......|..:|.|..:|.:|::.   :...::...:.|:.|.:|||..|||||:
Mouse   299 FGGHETTASAATSLITYLGLYPHVLQKVREEIKSKGLLCKSNQDNKLDMETLEQLKYTGCVIKET 363

  Fly   379 LRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPDYFPDPEKFIPDRFSMERKGEIS 443
            |||.|.||...|...:...|:|..||...|||..|.......|.|.:.|:|.||||.:....:.|
Mouse   364 LRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVADIFTNKEEFNPDRFIVPHPEDAS 428

  Fly   444 PFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRH--FELL------PLGEEVQPVLNVILRST 498
            .|::.||..|.|:|:|::||.:.:|....::.||  ::||      .....|.||.|:..|.|
Mouse   429 RFSFIPFGGGLRSCVGKEFAKILLKIFTVELARHCDWQLLNGPPTMKTSPTVYPVDNLPARFT 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	113/455 (25%)
Cyp26a1	NP_031837.2	CYP26A1	55..490	CDD:410731	115/480 (24%)