Protein Alignment Cyp4d14 and Cyp24a1

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_034126.1
• Gene: Cyp24a1 / 13081
• MGIID: 88593
• Length: 514
• Species: Mus musculus
• Alignment Length: 500
• Identity: 111/500 - (22%)
• Similarity: 214/500 - (42%)
• Gaps: 102/500 - (20%)

  Fly    35 GPKSYPLVGNAPLLINESPKSKSSIFDMQFRLIAEFGK---NIKTQMLGESGFMTADS-KMIEAI 95
            ||.::||:|:...:..:....|      |...:||:.|   .|....||....:...| .::||:
Mouse    60 GPTNWPLLGSLLEIFWKGGLKK------QHDTLAEYHKKYGQIFRMKLGSFDSVHLGSPSLLEAL 118

  Fly    96 MSSQ----QTIQ----------KNNLYSLLVNWLGDGLLISQGKKWFR-----RRKIITPAFHFK 141
            ..::    |.::          :|..|         ||:|.:|::|.|     ::|::.|....|
Mouse   119 YRTESAHPQRLEIKPWKAYRDHRNEAY---------GLMILEGQEWQRVRSAFQKKLMKPVEIMK 174

  Fly   142 -------ILEDFVEVFDQ--QSATMVQKLYDRADGKTVINMFPVACLCAMDIIAETAMGVKINAQ 197
                   :|.||:...|:  .....:|.||..      :|.:....:|.  ::.|...|:.....
Mouse   175 LDKKINEVLADFMGQIDELRDERGRIQDLYSE------LNKWSFESICL--VLYEKRFGLLQKDT 231

  Fly   198 LQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLFYPKLLDKLNDAVKNMHDFTNSVITER--- 259
            .:...|::.::.|..:...:..:.|::            |..:||..|...|......|.:.
Mouse   232 EEEALTFIAAIKTMMSTFGKMMVTPVE------------LHKRLNTKVWQAHTLAWDTIFKSVKP 284

  Fly   260 ---RELLQKAIADGGDADAALLNDVGQKRRMALLDVLLKSTIDGAPLSNDDIREEVDTFMFEGHD 321
               ..|.:.:...|.|    .|.|:.|:..                ||..::...|........:
Mouse   285 CIDHRLERYSQQPGAD----FLCDIYQQDH----------------LSKKELYAAVTELQLAAVE 329

  Fly   322 TTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVP 386
            ||.:|:.:..|.|:|:|:||.|:.:|::.|:.|:::.  ..:.:..:.||:..:|||:||.||||
Mouse   330 TTANSLMWILYNLSRNPQVQQRLLREIQSVLPDNQTP--RAEDVRNMPYLKACLKESMRLTPSVP 392

  Fly   387 IIGRYISQDTVLDGKLIPADSNVIILIYHAQ---RDPDYFPDPEKFIPDRFSMERKGEISPFAYT 448
            ...|.:.:.|||....:|..:   :|..:.|   ...|.|.|.:||.|:|: :|::.:|:|||:.
Mouse   393 FTTRTLDKPTVLGEYTLPKGT---VLTLNTQVLGSSEDNFEDADKFRPERW-LEKEKKINPFAHL 453

  Fly   449 PFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEEVQPVLNV 493
            ||..|.|.|||::.|.|::...:..:::.:.::....|...:|::
Mouse   454 PFGVGKRMCIGRRLAELQLHLALCWIIQKYNIVATDSEPVEMLHL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	102/463 (22%)
Cyp24a1	NP_034126.1	CYP24A1	90..508	CDD:410738	102/463 (22%)