Protein Alignment Cyp4d14 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 485
• Identity: 129/485 - (26%)
• Similarity: 238/485 - (49%)
• Gaps: 42/485 - (8%)

  Fly    36 PKSYPLVGNAPLLINESPKSKSSIFDMQFRLIAEFGKNIKTQMLGE-SGFMTADSKMIEAIMSS- 98
            |:...|:|:.|.| :::.::.|.:.|:.......:|...|..:|.. ..:.|:...:.|.:|||
 Frog    49 PRDSFLLGHIPTL-SKAEENYSVVHDLFLHWAEIYGPVFKINILHRVMIYSTSPESVKECLMSSK 112

  Fly    99 --QQTIQKNNLYSLL-VNWLGDGLLIS-QGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQ 159
              :.....|.|::|. ..:||.|||.. ....|:.:|:|:.|||....|::.:.:|::::..|::
 Frog   113 YPKDPYTYNQLFNLFGKRFLGKGLLTDPDHDHWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMME 177

  Fly   160 KLYDRADGKTVINMFPVACLCAMDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQ 224
            ||.::|||...::|..:.....:|:|.:.|.|:.:......:..:..:::.....:.....||..
 Frog   178 KLEEKADGHQEVSMHSIINRVTLDVITKVAFGMDLGLVEGNKTDFPNAISKVLTGMMRYMQNPYM 242

  Fly   225 RLDFTMKLFYPK---LLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRR 286
            :       ::||   .:.::.::...:.......|::|:    ||:.:|.:    |..|:
 Frog   243 Q-------YFPKHWAFVREVQESADLLRKTGKECISQRK----KAMQNGEE----LPKDI----- 287

  Fly   287 MALLDVLLKSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDV 351
              |..:|..:.::.| |.::.:.:...||...|.:||.:.::||...|.|.||:..::..||.:|
 Frog   288 --LTKILQCAELENA-LDDEIMLDNFITFFIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEV 349

  Fly   352 IGDDKSAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILIYHA 416
            ||..:.  ::...:..|.|:..|:|||||.:|..|...||:.:||:.:|..||...::....|..
 Frog   350 IGFKRD--ISYDDIQNLNYMTQVLKESLRFYPPGPGTSRYLKEDTIFEGIKIPGGVSITFNTYVM 412

  Fly   417 QRDPDYFPDPEKFIPDRFSMERKGEISP-FAYTPFSAGPRNCIGQKFAMLEMKSTISKMVR--HF 478
            .|...:|.||.||.|:||   ....:.| |.|.||:.|||:|:||.|:.||.|..:||:::  .|
 Frog   413 GRMEKFFQDPCKFDPERF---HPAAVKPYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRFEF 474

  Fly   479 ELLPLGEEVQPVLNVILRSTTGINCGLKPR 508
            ||:| |:.........||...|:.|.||.|
 Frog   475 ELVP-GQSFGIKDTGTLRPRDGVVCTLKSR 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	118/443 (27%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	119/454 (26%)