Protein Alignment Cyp4d14 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_001259179.1
• Gene: Cyp4d14 / 45706
• FlyBaseID: FBgn0023541
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 541
• Identity: 143/541 - (26%)
• Similarity: 246/541 - (45%)
• Gaps: 112/541 - (20%)

  Fly     8 ILLATALAWDYMRKRRHNKMYAEAGIRGPKSYPLVGNAPLLIN-------------ESPKSKSSI 59
            :|||..|...|....|.:.::.:.||.|||..|.:|.   ::|             |.......:
Mouse    13 VLLAIILVLLYRYGTRTHGLFKKQGIPGPKPLPFLGT---VLNYYKGLWKFDMECYEKYGKTWGL 74

  Fly    60 FDMQFRLIAEFGKNIKTQMLGESGFMTADSKMIEAIMSSQQTIQKNNLYSLLVN--------WLG 116
            ||.|..|                 |:..|.:||:.::..:       .:|:..|        .:.
Mouse    75 FDGQMPL-----------------FVITDPEMIKNVLVKE-------CFSVFTNRREFGPVGIMS 115

  Fly   117 DGLLISQGKKWFRRRKIITPAFHFKILEDFVEVFDQQSATMVQKLYDRADGKTVINMFPVACLCA 181
            ..:.||:.::|.|.|.:::|.|....|::...|.:|....:|:.|...|:....:.|..|....:
Mouse   116 KAISISKDEEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYS 180

  Fly   182 MDIIAETAMGVKINAQLQPQFTYVQSVTTASAMLAERFMNPLQRLDFTMKLF------------- 233
            :|:|..|:.||.:::...|:..:|:.   |..:|...|.:||.   |::.||
Mouse   181 IDVITSTSFGVNVDSLNNPEDPFVEK---AKGILRVDFFDPLV---FSVVLFPFLTPVYEMLNIC 239

  Fly   234 -YPKLLDKLNDAVKNMHDFTNSVITERRELLQKAIADGGDADAALLNDVGQKRRMALLDVLL--- 294
             :||      |:::....|.|.:...|.                   |..||.|:..|.:::
Mouse   240 MFPK------DSIEFFKKFVNRMKESRL-------------------DSKQKHRVDFLQLMMNAH 279

  Fly   295 ---KSTIDGAPLSNDDIREEVDTFMFEGHDTTTSSIAFTCYLLARHPEVQARVFQEVRDVIGDDK 356
               |.......||:.:|..:...|:|.|::||:|:::||.|.||.||::|.::.:|:.:.:  ..
Mouse   280 NNSKDKDSHKALSDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQEEIDETL--PN 342

  Fly   357 SAPVTMKLLGELKYLECVIKESLRLFPSVPIIGRYISQDTVLDGKLIPADSNVIILIYHAQRDPD 421
            .||.|...:.|::||:.|:.|:|||:|....:.|:..:|..|:|..||..|.|:|..|....||.
Mouse   343 KAPPTYDTVMEMEYLDMVLNETLRLYPIGNRLERFCKKDVELNGVYIPKGSTVMIPSYALHHDPQ 407

  Fly   422 YFPDPEKFIPDRFSMERKGEISPFAYTPFSAGPRNCIGQKFAMLEMKSTISKMVRHFELLPLGEE 486
            ::|:||:|.|:|||.|.||.|.|:.|.||..|||||||.:||.:.||..::|::::|...|..|.
Mouse   408 HWPEPEEFQPERFSKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTKVMQNFSFQPCQET 472

  Fly   487 -----------VQPVLNVILR 496
                       :||...::|:
Mouse   473 QIPLKLSRQGLLQPEKPIVLK 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4d14	NP_001259179.1	CYP4	71..503	CDD:410721	124/465 (27%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	127/482 (26%)