Protein Alignment milt and Trak2

DIOPT Version :10

• Sequence 1: NP_001245927.1
• Gene: milt / 45683
• FlyBaseID: FBgn0262872
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_008765294.1
• Gene: Trak2 / 171086
• RGDID: 620915
• Length: 932
• Species: Rattus norvegicus
• Alignment Length: 970
• Identity: 244/970 - (25%)
• Similarity: 397/970 - (40%)
• Gaps: 246/970 - (25%)

  Fly   230 ELPQELLQAAS-------SWEVMYYASKNVDGKNCLKVVRSLLTNK--VLCGNRVSQMTRAYDDI 285
            :|||..|:..|       .|....:..:  |....|..|.:..|.:  :|..:||.|||:.|:||
  Rat    50 QLPQYKLRVDSLFLYENQDWSQSSHQQQ--DASETLSPVLAEETFRYMILGTDRVEQMTKTYNDI 112

  Fly   286 EAVTRLLEEKEKDLELTVQIGKELLTQNNALEARVADLETDLKASNDDRAQLVHELHKKNEL--- 347
            :.||.||.|:::||||..:||:.||.:|:.|..:...||..|..:.|...||.|||.||.||
  Rat   113 DMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELSKKEELLRI 177

  Fly   348 ISVLTNDADDGTDTDTP-------TMSKS-ITLDLLQRKVNSLLDENKSLK-------------- 390
            :|:.:.:::..:...||       ::|:. :.||::..|:..|.:||.:|:
  Rat   178 VSIASEESETDSSCSTPLRFNESFSLSQGLLQLDMMHEKLKELEEENMALRSKVHLAFLSFSAVW 242

  Fly   391 -----CEATQLAHQTDEVEEHERQLMADISAQLNDANSQYDNLSLELERQREENRLQHEQIVNLT 450
                 .||..:..:|...||.|::|:.|...:|.:.|:|...::.||..:.:|.....|:|.:|.
  Rat   243 SGLGNTEACHIKTETFTYEEKEQKLINDCVNELRETNAQMSRMTEELSGKSDELLRYQEEISSLL 307

  Fly   451 ARLAEAEMRLHQLTQDNDEHLSLLHVTKENQNALALELVEFKQRYEEVLALLHSAQDQLKQQRKR 515
            :::.:.:.:|.:...:.:|....|..:|:.|..|.:||.|.:.|..|.|.:||.:|:::|:.|.:
  Rat   308 SQIVDLQHKLKEHVIEKEELRLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRNK 372

  Fly   516 SQPQARSSFLGGLGTSGAGMGGSLFPPDSLHCELMESSLYSENSLDSGISGDSQRSADRISRMMM 580
            :.|.|...|....|         :|..:||..|: |.::..:.|||.
  Rat   373 AGPSAHLCFSQAYG---------VFAGESLAAEI-EGTMRKKLSLDE------------------ 409

  Fly   581 HMPSGGMSSSTMGGSVYAGAGNVPPYKRVFDTVRCAGKSGNYMDSGNVSMTQLGAMSMSSSSGPR 645
                         .||:.....   .|||||||:.|.      |:...|:|....:.:..|:...
  Rat   410 -------------ESVFKQKAQ---QKRVFDTVKVAN------DTRGRSVTFPVLLPIPGSNRSS 452

  Fly   646 MASMAYPAGSYYRGGSNQSLGVKTLSSESLNSQ-SDDGYPAQPSGVPGAPGAKELEAALKRLTPA 709
            :...|.|    :..|..|:.. |||.::..::: ..:.:|..|   ||.|...:|..||.||:
  Rat   453 VIMTAKP----FESGVQQTED-KTLPNQGSSTEVPGNSHPRDP---PGLPEDSDLATALHRLS-- 507

  Fly   710 EVLARRAMLSYAPAGTYNYDEPMGHGTGNVRNSDLPLGVRTPDSIMSTGSSGMSGSTNHMSASMT 774
              |.|:..||........::.            .|.:.....:.:     |.....|.::::..|
  Rat   508 --LRRQNYLSEKQFFAEEWER------------KLQILAEQEEEV-----SSCEALTENLASFCT 553

  Fly   775 HQWR-------------LPEKLQIIKPMEGSQTLHHWSRLATPTLSGLLDERPGVTIRGGRGLDD 826
            .|..             :||||||:||:|||||||||.:||.|.|..:||.||||..:|...:..
  Rat   554 DQSETTELGSAGCLRGFMPEKLQIVKPLEGSQTLHHWQQLAQPNLGTILDPRPGVITKGFTQMPK 618

  Fly   827 LGMQIYTLSDVEED-----------------------------------------VSDDLPGKQF 850
              ..:|.:||:|||                                         |:...|||..
  Rat   619 --DAVYHISDLEEDEEVGITFQVQQPLQLEQKPAPPPPVTGIFLPPMTSAGGPVSVATSNPGKCL 681

  Fly   851 EAPGCTFTYTNSMVMHPDD-GFVNDLSFLSQSQMSSRMASTSTSRQPSCPATPRAGL-----SRK 909
            .....|||:|...::||.| ..|...|........|...|.|.:...|..|:.|..:     :|:
  Rat   682 SFTNSTFTFTTCRILHPSDITQVTPSSGFPSLSCGSSAGSASNTAVNSPAASYRLSIGESITNRR 746

  Fly   910 NSCSTFSVNLGLAGMLNERGIKA--------------VTPSALNTPAGPNFSPTVTPCNSPEGSP 960
            :|..|||....||.:|.||||.|              :.|.||.||:.|..||:.:||:||....
  Rat   747 DSTITFSSTRSLAKLLQERGISAKVYHSPASENPLLQLRPKALATPSTPPNSPSQSPCSSPVPFE 811

  Fly   961 PRAQSPEPLFGLLSCGADLIRRKIVGDQHQQQQQKQRSSLSKQQQQKIMLSHLERRALRSLNLIE 1025
            ||....|..  |.|..|:...:::.|         .|.|.:.....::           .:||::
  Rat   812 PRVHVSENF--LASRPAETFLQEMYG---------LRPSRAPPDVGQL-----------KMNLVD 854

  Fly  1026 KVESIGLENII------------SAQRGL------------GS---GIANRSSSPLSSGS 1058
            :::.:|:..::            .|:.||            ||   |:....|.|:..||
  Rat   855 RLKRLGIARVVKTPVPRENGKSREAEMGLQKPDSAVYLNSGGSLLGGLRRNQSLPVMMGS 914

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
milt	NP_001245927.1	HAP1_N	261..515	CDD:461455	84/285 (29%)
		Milton	614..792	CDD:463588	40/191 (21%)
Trak2	XP_008765294.1	HAP1_N	48..372	CDD:461455	92/323 (28%)
		Milton	433..584	CDD:463588	38/179 (21%)