Protein Alignment milt and trak1

DIOPT Version :10

• Sequence 1: NP_001245927.1
• Gene: milt / 45683
• FlyBaseID: FBgn0262872
• Length: 1256
• Species: Drosophila melanogaster
• Sequence 2: XP_017950014.1
• Gene: trak1 / 100135152
• XenbaseID: XB-GENE-5992917
• Length: 960
• Species: Xenopus tropicalis
• Alignment Length: 1068
• Identity: 291/1068 - (27%)
• Similarity: 439/1068 - (41%)
• Gaps: 278/1068 - (26%)

  Fly   225 EAPHFELPQELLQA--ASSWEVMYYASKNVDGKNCLKVVRSLLTNKVLCGNRVSQMTRAYDDIEA 287
            :.||::|..:.:..  ...|......|.:.:.....:.:...|...:||..||.|||:.|:||:|
 Frog    21 QLPHYKLRADTIYGYDHDDWLQTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDA 85

  Fly   288 VTRLLEEKEKDLELTVQIGKELLTQNNALEARVADLETDLKASNDDRAQLVHELHKKNELISVLT 352
            |||||||||:||||..:||:.||.:|.||..|...||..::...::.:||.|||..|:||:...|
 Frog    86 VTRLLEEKERDLELAARIGQSLLKKNKALTERNEYLEEQVEHIKEEVSQLRHELSMKDELLQFYT 150

  Fly   353 NDADDG---TDTDTP--------TMSKSITLDLLQRKVNSLLDENKSLKCEATQLAHQTDEVEEH 406
            :.|::.   :...||        ::......|.||:|:..|.|||..|:.||..|..:|...||.
 Frog   151 SAAEESEPESICSTPLKRNESASSVQNYFHFDSLQKKLKDLEDENIVLRSEACHLKTETITYEEK 215

  Fly   407 ERQLMADISAQLNDANSQYDNLSLELERQREENRLQHEQIVNLTARLAEAEMRLHQLTQDNDEHL 471
            |:||:.|...:|.|||.|..::|.||.::.::...|.|:|.:|.:::.:.:.:......:|:|.:
 Frog   216 EQQLVNDCVKELRDANVQIVSISEELAKKTDDAARQQEEITHLLSQIVDIQKKAKAYAVENEELV 280

  Fly   472 SLLHVTKENQNALALELVEFKQRYEEVLALLHSAQDQLKQQRKRSQPQARSSFLGGLGTSGAGMG 536
            ..|...|:.|..|..||.|.:.:|.|.:.:||.||::||..|.::.|...|.....||
 Frog   281 QHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNVISRRYHTLG------- 338

  Fly   537 GSLFPPDSLHCELMESSLYSENSLDSGISGDSQRSADRISRMMMHMPSGGMSSSTMGGSVYAGAG 601
              :||.|||..|: |.|:..|..:|.                        ..|..|.|:
 Frog   339 --VFPLDSLAAEI-EGSMRKELQMDE------------------------PDSPEMNGN------ 370

  Fly   602 NVPPYKRVFDTVRCAGKSGNYMDSGNVSMTQLGAMSMSSSSGPRMASMAYPAGSYYRGG-SNQSL 665
               .:||||:||:...:...........|...|:...|:.:....:.::.|..|.|.|. ||..:
 Frog   371 ---HHKRVFETVKNVNQVVKQRSLAPSPMNIPGSNQSSAMNSLMSSCVSTPRSSLYGGDVSNIVI 432

  Fly   666 GVKT----LSSESLNSQSDDGYPAQPSGVPGAPGAKELEAALKRLTPAE---VLAR--------R 715
            ..||    |.:||..:...:|...:..|.||.||:.:||.||:||:...   :|.|        |
 Frog   433 DNKTNSIILETESSENSLSNGDKNKKPGTPGTPGSSDLETALRRLSLRRENYILERKFFEDDQER 497

  Fly   716 AMLSYAPAGTYNYDEPMGHGTGNVRNSDLPLGVRTP-DSIMS----------TGSSGMSGSTNHM 769
            .:.|.|..|..:        :|:|          || |||||          ||.||||.|:...
 Frog   498 KLRSLAEKGEIH--------SGSV----------TPTDSIMSLGTHSRLSEFTGVSGMSYSSRSY 544

  Fly   770 SASMTHQWRLPEKLQIIKPMEGSQTLHHWSRLATPTLSGLLDERPGVTIRGGRGLDDLGMQIYTL 834
                     |||||||:||:|||.|||||.:||.|.|.|:||.||||..:|.|.||.....:|..
 Frog   545 ---------LPEKLQIVKPLEGSATLHHWQQLAQPNLGGILDPRPGVVTKGFRTLDLDQEDVYCF 600

  Fly   835 SDVEEDVSDDLPGKQFEA----------------------------------------------- 852
            :|.|||.:.|:|.|.|..
 Frog   601 TDYEEDETGDIPFKSFTTSPSIQHSETSGERSQAQVTVSDSKNCPSHSQAAPEDLQEPATDDDEG 665

  Fly   853 ----PG-C------TFTYTNSMVMHPDDGFVNDLSFLSQ---------SQMSSRMASTSTSRQPS 897
                || |      |||:|...::||.|........|:.         :.:.|..|||
 Frog   666 SVYYPGKCMSQTNSTFTFTTCRILHPSDELTRVTPSLNAVPTPACGNLNNLKSTPAST------- 723

  Fly   898 CPATPR------AGLSRKNSCSTFSVNLGLAGMLNERGIKAVT-------------------PSA 937
             |.|||      :..:.:.|.:|.|.:|||..:|.||||.|..                   |..
 Frog   724 -PCTPRRLSLAESFTNLRESTTTMSTSLGLVRLLKERGISAAVYNPQTWDRAGKASLINHTLPKM 787

  Fly   938 LNTPAGPNFSPTVTPCNSPEGSPPRAQSPEPLFGLLSCGADLIRRKIVGDQHQQQQQKQRSSLSK 1002
            ...|:.|..||..||.:||.....:..|| |....|:                   .|..||:.|
 Frog   788 AIIPSTPPNSPMPTPNSSPPSLDFKCTSP-PYDNFLA-------------------SKPASSILK 832

  Fly  1003 QQQQKIMLSHLERR---ALRSLNLIEKVESIGLENIISAQRGLGSGIANRSSSPLSSGSLQSLHT 1064
            :.::|..:...|.:   ::.:|||::||:..|:..                    :|||     |
 Frog   833 EVREKKNIRSSECQTDVSVSNLNLVDKVKKFGIAK--------------------ASGS-----T 872

  Fly  1065 SSNSIVDDIHFDRAQIKGVLHRGLKSPTPATASTSAAAAASGPGISTSSSTSAYNSDDSDDQGLV 1129
            .::::.|            .|:|.:.  ||...........|..|:..:.|||..:     ..|.
 Frog   873 VTHALSD------------CHKGTQG--PARTYVPGGLVPEGLPINYPAVTSAIGA-----LHLN 918

  Fly  1130 MKIKPSKSATPTTTGAAQSQPSSATTSN 1157
            ..|:.::| .||..|::......||.::
 Frog   919 SGIRRNRS-FPTMVGSSMQMKGPATLTS 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
milt	NP_001245927.1	HAP1_N	261..515	CDD:461455	96/264 (36%)
		Milton	614..792	CDD:463588	58/204 (28%)
trak1	XP_017950014.1	HAP1_N	19..324	CDD:461455	101/302 (33%)
		Milton	387..558	CDD:463588	58/197 (29%)