Protein Alignment Vha68-1 and VMA1

DIOPT Version :9

• Sequence 1: NP_001260426.1
• Gene: Vha68-1 / 45668
• FlyBaseID: FBgn0265262
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_010096.1
• Gene: VMA1 / 851342
• SGDID: S000002344
• Length: 1071
• Species: Saccharomyces cerevisiae
• Alignment Length: 1061
• Identity: 385/1061 - (36%)
• Similarity: 486/1061 - (45%)
• Gaps: 462/1061 - (43%)

  Fly     9 DEERESEYGRVYAVSGPVVTAEAMSGSAMYELVRVGYYELVGEIIRLEGDMATIQVYEETSGVTV 73
            ::..|||||.:|:||||||.||.|.|.||||||:||:..||||:||::||.|||||||||:|:||
Yeast    18 EDHAESEYGAIYSVSGPVVIAENMIGCAMYELVKVGHDNLVGEVIRIDGDKATIQVYEETAGLTV 82

  Fly    74 GDPVLRTGKPLSVELGPGIMGSIFDGIQRPLRDIGVMTNSIYIPKGVNTTALSRSEMWEFNPLNV 138
            ||||||||||||||||||:|.:|:|||||||:.|...:.|||||:|::|.||.|:..|:|.|...
Yeast    83 GDPVLRTGKPLSVELGPGLMETIYDGIQRPLKAIKEESQSIYIPRGIDTPALDRTIKWQFTPGKF 147

  Fly   139 RVGSHITGGDLYGVVHENTLV-KQRMIVAPRAKGTVRYIAPAGNYNLEDIVLETEFDGEITKHTM 202
            :||.||:|||:||.|.||:|: ..::::.||::||:.:|||||.|.|::.:||.||||:.:..|:
Yeast   148 QVGDHISGGDIYGSVFENSLISSHKILLPPRSRGTITWIAPAGEYTLDEKILEVEFDGKKSDFTL 212

  Fly   203 LQVWPVRQPRPVTEKLPANHPLFTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKYSNSD 267
            ...||||.||||||||.|::||.|||||||:||||||||||.||||||||||||||:||||||||
Yeast   213 YHTWPVRVPRPVTEKLSADYPLLTGQRVLDALFPCVQGGTTCIPGAFGCGKTVISQSLSKYSNSD 277

  Fly   268 VIIYVG----------------------------------------------------------- 273
            .|||||
Yeast   278 AIIYVGCFAKGTNVLMADGSIECIENIEVGNKVMGKDGRPREVIKLPRGRETMYSVVQKSQHRAH 342

  Fly   274 ----------------------------------------------------------------- 273
                                                                             
Yeast   343 KSDSSREVPELLKFTCNATHELVVRTPRSVRRLSRTIKGVEYFEVITFEMGQKKAPDGRIVELVK 407

  Fly   274 ----------------------------------------------------------------- 273
                                                                             
Yeast   408 EVSKSYPISEGPERANELVESYRKASNKAYFEWTIEARDLSLLGSHVRKATYQTYAPILYENDHF 472

  Fly   274 ----------------------------------------------------------------- 273
                                                                             
Yeast   473 FDYMQKSKFHLTIEGPKVLAYLLGLWIGDGLSDRATFSVDSRDTSLMERVTEYAEKLNLCAEYKD 537

  Fly   274 ----------------------------------------------------------------- 273
                                                                             
Yeast   538 RKEPQVAKTVNLYSKVVRGNGIRNNLNTENPLWDAIVGLGFLKDGVKNIPSFLSTDNIGTRETFL 602

  Fly   274 ----------------------------------------------------------------- 273
                                                                             
Yeast   603 AGLIDSDGYVTDEHGIKATIKTIHTSVRDGLVSLARSLGLVVSVNAEPAKVDMNGTKHKISYAIY 667

  Fly   274 ----------------------------------------------------------------- 273
                                                                             
Yeast   668 MSGGDVLLNVLSKCAGSKKFRPAPAAAFARECRGFYFELQELKEDDYYGITLSDDSDHQFLLANQ 732

  Fly   274 -----CGERGNEMSEVLRDFPELTCEIDGVTESIMKRTALVANTSNMPVAAREASIYTGITLSEY 333
                 ||||||||:|||.:||||..|:.|..|.|||||.|||||||||||||||||||||||:||
Yeast   733 VVVHNCGERGNEMAEVLMEFPELYTEMSGTKEPIMKRTTLVANTSNMPVAAREASIYTGITLAEY 797

  Fly   334 FRDMGYNVAMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLATFYERAGRVKCLGNPERE 398
            |||.|.||:|:|||:||||||||||||||.|||||.|:||||||:||:||||||:...||:|:|.
Yeast   798 FRDQGKNVSMIADSSSRWAEALREISGRLGEMPADQGFPAYLGAKLASFYERAGKAVALGSPDRT 862

  Fly   399 GSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRALDEYYD 463
            ||||||.||||.|||||||||:|||||.||||||||||||||||||||..:|||||...|:::||
Yeast   863 GSVSIVAAVSPAGGDFSDPVTTATLGITQVFWGLDKKLAQRKHFPSINTSVSYSKYTNVLNKFYD 927

  Fly   464 KNYPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKVTLEVAKLLKDDFLQQNSYSPYDRV 528
            .|||||..||.::||||...|:|.::||||||::|:::||:||:||.|:|:||||||.||.||..
Yeast   928 SNYPEFPVLRDRMKEILSNAEELEQVVQLVGKSALSDSDKITLDVATLIKEDFLQQNGYSTYDAF 992

  Fly   529 CPFYKTVGMLRNIMAFYETARHAVESTAQSDNKITWNTIRESMGGIMYQLSSMKFKDPVKDGEQK 593
            ||.:||..|:|..:::::.|:.||.      |...|:.:.:|.|.:.:.:||.||.:|.: ||::
Yeast   993 CPIWKTFDMMRAFISYHDEAQKAVA------NGANWSKLADSTGDVKHAVSSSKFFEPSR-GEKE 1050

  Fly   594 IKADYDQLYEDLQQAFRNLED 614
            :..::::|...:|:.|....|
Yeast  1051 VHGEFEKLLSTMQERFAESTD 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha68-1	NP_001260426.1	V-ATPase_V1_A	15..606	CDD:273411	380/1045 (36%)
VMA1	NP_010096.1	V-ATPase_V1_A	24..>293	CDD:273411	173/268 (65%)
		Hom_end_hint	284..736	CDD:368334	0/451 (0%)
		V-ATPase_V1_A	<733..1063	CDD:273411	207/336 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343963
Domainoid	1	1.000	147	1.000	Domainoid score	I966
eggNOG	1	0.900	-	-		E1_COG1155
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H123934
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S546
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001869
OrthoInspector	1	1.000	-	-		otm46705
orthoMCL	1	0.900	-	-		OOG6_100902
Panther	1	1.100	-	-	O	PTHR43607
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1565
TreeFam	1	0.960	-	-
	12	11.650