DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Vha68-1 and VHA-A

DIOPT Version :9

Sequence 1:	NP_001260426.1	Gene:	Vha68-1 / 45668	FlyBaseID:	FBgn0265262	Length:	614	Species:	Drosophila melanogaster
Sequence 2:	NP_001031299.1	Gene:	VHA-A / 844228	AraportID:	AT1G78900	Length:	623	Species:	Arabidopsis thaliana

Alignment Length:	613	Identity:	420/613 - (68%)
Similarity:	496/613 - (80%)	Gaps:	3/613 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LRKFKDEERESEYGRVYAVSGPVVTAEAMSGSAMYELVRVGYYELVGEIIRLEGDMATIQVYEET 68
            |..|:|:|:|||||.|..||||||.|:.|:|:|||||||||:..|:|||||||||.|||||||||
plant     9 LTTFEDDEKESEYGYVRKVSGPVVVADGMAGAAMYELVRVGHDNLIGEIIRLEGDSATIQVYEET 73

  Fly    69 SGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLRDIGVMTNSIYIPKGVNTTALSRSEMWEF 133
            :|:||.||||||.|||||||||||:|:|||||||||:.|..::..:|||:||:..||.:..:|||
plant    74 AGLTVNDPVLRTHKPLSVELGPGILGNIFDGIQRPLKTIARISGDVYIPRGVSVPALDKDCLWEF 138

  Fly   134 NPLNVRVGSHITGGDLYGVVHENTLVKQRMIVAPRAKGTVRYIAPAGNYNLEDIVLETEFDGEIT 198
            .|.....|..|||||||..|.||||:...:.:.|.|.|.:.||||||.|:|:|.|:|.||.|...
plant   139 QPNKFVEGDTITGGDLYATVFENTLMNHLVALPPDAMGKITYIAPAGQYSLKDTVIELEFQGIKK 203

  Fly   199 KHTMLQVWPVRQPRPVTEKLPANHPLFTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQALSKY 263
            .:||||.||||.||||..||.|:.||.|||||||:|||.|.|||.||||||||||||||||||||
plant   204 SYTMLQSWPVRTPRPVASKLAADTPLLTGQRVLDALFPSVLGGTCAIPGAFGCGKTVISQALSKY 268

  Fly   264 SNSDVIIYVGCGERGNEMSEVLRDFPELTCEI-DGVTESIMKRTALVANTSNMPVAAREASIYTG 327
            ||||.::|||||||||||:|||.|||:||..: ||..||:||||.||||||||||||||||||||
plant   269 SNSDAVVYVGCGERGNEMAEVLMDFPQLTMTLPDGREESVMKRTTLVANTSNMPVAAREASIYTG 333

  Fly   328 ITLSEYFRDMGYNVAMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLATFYERAGRVKCL 392
            ||::||||||||||:|||||||||||||||||||||||||||||||||.||||:||||||:||||
plant   334 ITIAEYFRDMGYNVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLAARLASFYERAGKVKCL 398

  Fly   393 GNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYMRA 457
            |.|||.|||:|||||||||||||||||||||.||||||||||||||||||||:|||||||||..|
plant   399 GGPERNGSVTIVGAVSPPGGDFSDPVTSATLSIVQVFWGLDKKLAQRKHFPSVNWLISYSKYSTA 463

  Fly   458 LDEYYDKNYPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKVTLEVAKLLKDDFLQQNSY 522
            |:.:|:|..|:|:.:|||.:|:||.|:||:||||||||.:|||.||:|||.||||::|:|.||::
plant   464 LESFYEKFDPDFINIRTKAREVLQREDDLNEIVQLVGKDALAEGDKITLETAKLLREDYLAQNAF 528

  Fly   523 SPYDRVCPFYKTVGMLRNIMAFYETARHAVESTAQSD-NKITWNTIRESMGGIMYQLSSMKFKDP 586
            :|||:.|||||:|.|:|||:.||..|..|||..|..| .|||:..|:..:|.:.|:|.|.||:||
plant   529 TPYDKFCPFYKSVWMMRNIIHFYNLANQAVERAAGMDGQKITYTLIKHRLGDLFYRLVSQKFEDP 593

  Fly   587 VKDGEQKIKADYDQLYEDLQQAFRNLED 614
            . :||..:...:.:||:||...||.|||
plant   594 A-EGEDTLVEKFKKLYDDLNAGFRALED 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha68-1	NP_001260426.1	V-ATPase_V1_A	15..606	CDD:273411	408/592 (69%)
VHA-A	NP_001031299.1	V-ATPase_V1_A	20..611	CDD:273411	407/591 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	404	1.000	Domainoid score	I135
eggNOG	1	0.900	-	-		E1_COG1155
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H123934
Inparanoid	1	1.050	848	1.000	Inparanoid score	I68
OMA	1	1.010	-	-		QHG60789
OrthoDB	1	1.010	-	-		D241249at2759
OrthoFinder	1	1.000	-	-		FOG0001869
OrthoInspector	1	1.000	-	-		otm2949
orthoMCL	1	0.900	-	-		OOG6_100902
Panther	1	1.100	-	-	O	PTHR43607
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1565
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840