Protein Alignment Vha68-1 and Atp6v1a

DIOPT Version :10

• Sequence 1: NP_523560.2
• Gene: Vha68-1 / 45668
• FlyBaseID: FBgn0265262
• Length: 614
• Species: Drosophila melanogaster
• Sequence 2: NP_001101788.1
• Gene: Atp6v1a / 685232
• RGDID: 1596464
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 510/614 - (83%)
• Similarity: 563/614 - (91%)
• Gaps: 1/614 - (0%)

  Fly     2 SNLRKFKDEERESEYGRVYAVSGPVVTAEAMSGSAMYELVRVGYYELVGEIIRLEGDMATIQVYE 66
            |.|.|.:||::||.:|.|:.||||||||..|:|:|||||||||:.||||||||||||||||||||
  Rat     4 SKLPKIRDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYE 68

  Fly    67 ETSGVTVGDPVLRTGKPLSVELGPGIMGSIFDGIQRPLRDIGVMTNSIYIPKGVNTTALSRSEMW 131
            |||||:||||||||||||||||||||||:|||||||||.||...|.|||||:|||.:||||...|
  Rat    69 ETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDIKW 133

  Fly   132 EFNP-LNVRVGSHITGGDLYGVVHENTLVKQRMIVAPRAKGTVRYIAPAGNYNLEDIVLETEFDG 195
            ||.| .|:||||||||||:||:|:||:|:|.::::.||::|:|.||||.|||:..|:|||.||:|
  Rat   134 EFIPSKNLRVGSHITGGDIYGIVNENSLIKHKIMLPPRSRGSVTYIAPPGNYDASDVVLELEFEG 198

  Fly   196 EITKHTMLQVWPVRQPRPVTEKLPANHPLFTGQRVLDSLFPCVQGGTTAIPGAFGCGKTVISQAL 260
            ...|.:|:|||||||.|||||||||||||.|||||||:|||||||||||||||||||||||||:|
  Rat   199 VKEKLSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSL 263

  Fly   261 SKYSNSDVIIYVGCGERGNEMSEVLRDFPELTCEIDGVTESIMKRTALVANTSNMPVAAREASIY 325
            ||||||||||||||||||||||||||||||||.|:||..||||||||||||||||||||||||||
  Rat   264 SKYSNSDVIIYVGCGERGNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIY 328

  Fly   326 TGITLSEYFRDMGYNVAMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLATFYERAGRVK 390
            ||||||||||||||:|:||||||||||||||||||||||||||||||||||||||:|||||||||
  Rat   329 TGITLSEYFRDMGYHVSMMADSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVK 393

  Fly   391 CLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSINWLISYSKYM 455
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||
  Rat   394 CLGNPEREGSVSIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYM 458

  Fly   456 RALDEYYDKNYPEFVPLRTKVKEILQEEEDLSEIVQLVGKASLAETDKVTLEVAKLLKDDFLQQN 520
            |||||||||::.||||||||.||||||||||:||||||||||||||||:|||||||:||||||||
  Rat   459 RALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQN 523

  Fly   521 SYSPYDRVCPFYKTVGMLRNIMAFYETARHAVESTAQSDNKITWNTIRESMGGIMYQLSSMKFKD 585
            .|:||||.||||||||||.|:::||:.||.|||:||||||||||:.|||.||.|:|:||||||||
  Rat   524 GYTPYDRFCPFYKTVGMLSNMISFYDMARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKD 588

  Fly   586 PVKDGEQKIKADYDQLYEDLQQAFRNLED 614
            ||||||.||||||.||.||:|.|||:|||
  Rat   589 PVKDGEAKIKADYAQLLEDMQNAFRSLED 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Vha68-1	NP_523560.2	V-ATPase_V1_A	15..606	CDD:273411	496/591 (84%)
Atp6v1a	NP_001101788.1	V-ATPase_V1_A	17..609	CDD:273411	496/591 (84%)