Protein Alignment dom and RAD5

DIOPT Version :10

• Sequence 1: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Sequence 2: NP_197667.1
• Gene: RAD5 / 832338
• AraportID: AT5G22750
• Length: 1029
• Species: Arabidopsis thaliana
• Alignment Length: 1152
• Identity: 220/1152 - (19%)
• Similarity: 360/1152 - (31%)
• Gaps: 516/1152 - (44%)

  Fly   829 KRRKLAPRD-----PELDSDDDSTAVDSTEESEDAATEDEEDLSTVKTDTDMEEQDEQEDGLKSL 888
            |:.:..|.|     ..|.|.|.|....|..:           |:.||.    ..||...|..:..
plant   268 KKAEFTPEDFYSKKRPLSSKDGSAIPTSLLQ-----------LNKVKN----MNQDANGDENEQC 317

  Fly   889 MADADATSGAAGSGSTAGASGNKDDMLNDAAALAESLQPKGNTLSSTNVVTPVPFLLKHSLREYQ 953
            ::|.| .....|.|              |::.|.|               ...|..|...||.||
plant   318 ISDGD-LDNIVGVG--------------DSSGLKE---------------METPHTLLCELRPYQ 352

  Fly   954 HIGLDWLVTM-----------------------NERKL-----------------------NGIL 972
            ...|.|:..:                       ::|:|                       .|||
plant   353 KQALHWMTQLEKGNCTDEAATMLHPCWEAYCLADKRELVVYLNSFTGDATIHFPSTLQMARGGIL 417

  Fly   973 ADEMGLGKTIQTIA-LLAH--LACAKG----NW-------------------------------- 998
            ||.||||||:.||: ||||  .|.:.|    |:
plant   418 ADAMGLGKTVMTISLLLAHSWKAASTGFLCPNYEGDKVISSSVDDLTSPPVKATKFLGFDKRLLE 482

  Fly   999 -------GPHLIVVPSSVMLNWEMEFKKWC-PG-FKILTYYGSQKERKLKRVGWTKPNAFHVCIT 1054
                   |.:|||.|.:::..|:.|.:... || ..:..:||..:.:..|.:..:     .|.||
plant   483 QKSVLQNGGNLIVCPMTLLGQWKTEIEMHAKPGSLSVYVHYGQSRPKDAKLLSQS-----DVVIT 542

  Fly  1055 SYKLVVQ--------DQQSFRRKKWKYLILDEAQNIKNFKSQRWQLLLNFSTERRLLLTGTPLQN 1111
            :|.::..        |.:.....:|..::||||..|||.|||..........:||..|||||:||
plant   543 TYGVLTSEFSQENSADHEGIYAVRWFRIVLDEAHTIKNSKSQISLAAAALVADRRWCLTGTPIQN 607

  Fly  1112 DLMELWSLMHFLMPYVFSSHREFKEWFSNPMTGMIEGNMEYNETLITRLHKVIRPFLLRRLKKEV 1176
            :|.:|:||:.||....:.:...:.:....|..       |.:|..:..:..:::|.:|||.|...
plant   608 NLEDLYSLLRFLRIEPWGTWAWWNKLVQKPFE-------EGDERGLKLVQSILKPIMLRRTKSST 665

  Fly  1177 EKQ------MPKKYEHVITCRLSNRQRYLYEDFMSRAKTR--ETLQTGNLL----SVINVLMQLR 1229
            :::      :|.....||.|.||..:|..|:....|:|.:  :.::.|.:|    |::.:|::||
plant   666 DREGRPILVLPPADARVIYCELSESERDFYDALFKRSKVKFDQFVEQGKVLHNYASILELLLRLR 730

  Fly  1230 KVCNHPNMFEARPTISPFQMDGITFHTPRLVCDIMEYDPFTQINLETLNLLLLHLEQTMTAYVSH 1294
            :.|:||.:..:|.                   |..||
plant   731 QCCDHPFLVMSRG-------------------DTAEY---------------------------- 748

  Fly  1295 KSRLLAPPRKLIEDIDTAPLPAPRCPNGKYRFHIRVRSAELAQRIKLNAVKVGASPAMRLEGSKI 1359
                                                                             
plant   749 ----------------------------------------------------------------- 748

  Fly  1360 MPMRNLLPSGRVLKRVSASINPVNMALKPVVINSVVTTTSSSTTASSPTGALSVLSNSKLLGARS 1424
                                                                            |
plant   749 ----------------------------------------------------------------S 749

  Fly  1425 QINAPTPAKVAKTMQDGKPFFYLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTASTTSGQQL 1489
            .:|     |::|....||                                         :||.:
plant   750 DLN-----KLSKRFLSGK-----------------------------------------SSGLE- 767

  Fly  1490 IRDPIVKDLATHVKSTVQKQSIANGKTEPEEETEAEDPYKVQELI-QMRKEQRLAALKRMAMINR 1553
                                  ..||..|.|..       |||:: ::||.::
plant   768 ----------------------REGKDVPSEAF-------VQEVVEELRKGEQ------------ 791

  Fly  1554 RRTDATPIYGEDCREAIQRCMQATRSLKRSTWQTRGYANCCTAMAHRNGWSLNHLLKSFEERCAD 1618
               ...||    |.||::..:                   .|..|||  .....||.|:....:.
plant   792 ---GECPI----CLEALEDAV-------------------LTPCAHR--LCRECLLASWRNSTSG 828

  Fly  1619 LKPVFANFVIYVPSVCAPRIRRYVQNLSSTHWQHEQRIENIVDQALRPKLALLHPIISEMTTKFP 1683
            |.||..|.|.....:.||...|:..::.. :|....:|..::::
plant   829 LCPVCRNTVSKQELITAPTESRFQVDVEK-NWVESSKITALLEE--------------------- 871

  Fly  1684 DPRLIQYDCGKLQTMDRLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHGHIYLRLDGSTRVEQR 1748
                              |..|:.:|.:.::|:|.|..||:|:..|:.:...::||||:...:||
plant   872 ------------------LEGLRSSGSKSILFSQWTAFLDLLQIPLSRNNFSFVRLDGTLSQQQR 918

  Fly  1749 QILMERFNGDKRIFCFILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHI 1813
            :.:::.|:.|..|...::|.::||||||||.|......|..|||.::.||..|.||||||::|.|
plant   919 EKVLKEFSEDGSILVLLMSLKAGGVGINLTAASNAFVMDPWWNPAVEEQAVMRIHRIGQTKEVKI 983

  Fly  1814 YRLVSERTIEVNI-LKKANQKRMLSDMAIEGGNFTTTYFKSSTIKDL 1859
            .|.:.:.|:|..: ..:|.::||:|      |..|....:|:.|::|
plant   984 RRFIVKGTVEERMEAVQARKQRMIS------GALTDQEVRSARIEEL 1024

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dom	NP_001286676.1	HSA	543..614	CDD:214727
		HepA	692..>1235	CDD:440319	119/524 (23%)
		DEXQc_SRCAP	949..1171	CDD:350761	76/323 (24%)
		SF2_C_SNF	1685..1817	CDD:350180	45/131 (34%)
		DISARM_DrmD_b	<1702..>1936	CDD:468472	56/159 (35%)
		HEC1	<1858..>2031	CDD:444066	1/2 (50%)
		SP1-4_N	2486..>2819	CDD:425404
RAD5	NP_197667.1	UBA_like_SF	9..48	CDD:473871
		HIRAN	116..224	CDD:400928
		HepA	<339..1011	CDD:440319	195/1021 (19%)
		RING_Ubox	789..842	CDD:473075	17/92 (18%)