|
Fly 7 AGGGHEGLSPAP---PAVPD------------------RVT-PHSTEISV-APANSTSTTVRA-- 46
||.....|:|.| ||.|. :|| |.|.::.. :|....:..::|
Frog 85 AGNQQITLTPLPIPNPASPGFQFSSQPRRFEHGSPSYIQVTSPMSQQVQTQSPTQPNAMPIQALQ 149
Fly 47 ---AGSVGAAL-----PATRHHQHIATQVKGIASSSSK-------------QQKQLASAQLPVPL 90
.|:.||:| ..||.....:..|:.|:.|.|. |..|.|:||:.:|.
Frog 150 SVRTGTAGASLGMCSQSPTRGFVDASVLVRQISLSPSNGGHFVFQEGTGIAQIAQGATAQVQLPA 214
Fly 91 SP---------LPQQQQQTAEA------TAAAAAPAHSNVSVSSSTIEASVLPPQ---------- 130
.. |.|...||... .:..|:.|:.....:.|.|..:.||||
Frog 215 GAAQATMHERRLSQPHSQTGGTIHHLGPQSPVASGANMQTLTTPSHITTTNLPPQISSIIQGQLI 279
Fly 131 AKRQRLDDNE-------DRTSAASIVGPAESS-NIVSSLLPASVASSSEVGGLSS---------- 177
.::|.|...: ||||...|.|...:| .:.|...|.|.:.::...|||:
Frog 280 QQQQVLHGQQLGRAISFDRTSGGMIAGVTGASFGMTSPPTPTSPSRAAGPQGLSNLPLTTTVSTT 344
Fly 178 ------------TALQDLNALKKRILQQKLQILRNLKERHLENVSEYFYLQN-GGSMMDYPAWRK 229
.|.|:...::|:.|....:.::.|||...|.:.|.|:||: .|:|||:.|::|
Frog 345 HKKQCKKLEEIPPATQEEARMRKQCLDHHQKNMKVLKENFKEYLIELFFLQHFQGNMMDFLAFKK 409
Fly 230 KTPTPQFISYSNANRID----------QLIHED--------------------KPSTSAAAAAAQ 264
| ||.....|...|.:| ::|::: .|...:||.::|
Frog 410 K-PTLGLQGYLRQNDLDLEEEEEEEQSEVINDEVKIVTGKDGQTGTPVAIATQLPPNVSAAFSSQ 473
Fly 265 NQKYTTQQTDSVESSLVSGIGT-----------------------------------GATKGAPL 294
.|.: ||| ...|..|....| |.|.|.||
Frog 474 QQPF--QQT-LTGSGAVGAANTIDIEAFKRQQVLTQTDPSKRPRLDVPRHGMVFQHPGVTSGVPL 535
Fly 295 -------DGNI--SNSTV-----KTNTQSQVPSKIGSFTESTPAATESNSSTTVPGTATSGAATS 345
.|.: :..|| |.|.|...||| |...:: ||:.......:||...:.....
Frog 536 QQLMPTAQGGMPPTPQTVQLTGQKQNQQQYDPSK-GPPVQN--AASLHTPPPQLPGRVQASNIPI 597
Fly 346 TSATSA----------------EASGNVLAVEAEIKIPAVGATPVAISTKLPAAVVQLTQQGHIP 394
:|..:| :...|...::.:|: |.:.::.|...:..:.|..:|
Frog 598 SSLPTALHLAQQQQQQQQQQQQQQQINETQIQPQIQ--------VQVKSQPPNVQISASPQSQLP 654
Fly 395 ---GRPL-GGRHGMVFGQIPAPPAAVGNPSVPLVPGGTPLLPCNTSAGSTALRRPQGQNNASSGS 455
.:|| .|.|..: |.....||:...:|.||..||. .|.....|:| |.||....
Frog 655 LQISQPLQPGFHTQM--QTSQQQAAIQQQTVTLVRPGTD-SPQQRLTGNT-------QTNAFVAP 709
Fly 456 AAASGGGGSLTPTPLYTGNGP--------------AALGGSGGLTPGTPTSGSLLSPALGGGSGT 506
||.| |.:|:.:.:.| :...||.| |.||...|.|..|: |..|..
Frog 710 AAIS------TASPIASFSLPTNRALPATNKSMSVSKAPGSAG-TVGTKIQGQLQIPS-GLTSEN 766
Fly 507 PNSAAQEFSFKAKQEVYVMQRISELQREGLWTERRLPKLQEPSRPKAHWDYLLEEMVWLAADFAQ 571
|.....| :.|.|.:|.|||:||::||||:.|||||:|||||.|:|||||||||.|:||||||
Frog 767 PQDKLAE---QVKLENHVHQRIAELRKEGLWSLRRLPKIQEPSRAKSHWDYLLEEMQWMAADFAQ 828
Fly 572 ERKWKKNAAKKCAKMVQKYFQDKATAAQRAEKAQELQLKRVASFIAREVKSFWSNVEKLVEYKHQ 636
||.||:.:|||..:...:|..:|....:||:|.:|.:|||:|:.||||::.||||:|::||.|.|
Frog 829 ERMWKQASAKKLVRKAARYHDEKKMHFERAKKEEENKLKRIAASIAREIEYFWSNIEQVVEIKLQ 893
Fly 637 TKIEEKRKQALDQHLSFIVDQTEKFSQQLVEGMNKSVADTPSLNSSRLTSPKRESDDDFRPESGS 701
.:.:|||::|| :||:..:..|
Frog 894 MEFQEKRRKAL------------------------------NLNTESMKGP-------------- 914
Fly 702 EDDEETIAKAEEDAADVKEEVTALAKESEMDFDDFLNDLPPGYLENRDKLMKEEQSSAIKTETPD 766
.||.|:|. ||.:....:..|. |.:.||:.
Frog 915 -------LKAIEEAC-VKRDTNKASPTSR----------------------KRKASSSW------ 943
Fly 767 DSDDSEFEAKEASDDDENTISKQEEAEQEIDHKKEIDELEADNDLSVEQLLAKYKSEQPPSPKRR 831
||. |.:|:|.||::||..|..|||..|:.||..:.||.::.|:.:|:.....:....
Frog 944 -SDG-------AVEDEEETIAEQESKEGNIDHHAELCELAREADLPLDDLVKQYEGAYDQNFHWP 1000
Fly 832 KLAPRDPELDSDDDSTAVDSTEESEDAATEDEEDLSTVKTDTDMEEQDEQEDGLKSLMADADATS 896
:..|: :|||.:|..|.:| :||:: .|.::.....|.| |.||....:
Frog 1001 QTLPQ---------------SEESNNAKNESDE--ATVES-ADYQKPTVLIDFL--LCADQYRMA 1045
Fly 897 GAAGSGSTAGASGNKDDMLNDAAALAESLQPKGNTLSSTNVVTPVPFLLKHSLREYQHIGLDWLV 961
..|.||........:| :.|.|..||.|.|.||...::.....:|.||..|||:||.:|||||.
Frog 1046 DVASSGHLGSRKHTRD--IGDVARAAELLLPNGNARITSTEKKKLPCLLHGSLRDYQQVGLDWLE 1108
Fly 962 TMNERKLNGILADEMGLGKTIQTIALLAHLACAKGNWGPHLIVVPSSVMLNWEMEFKKWCPGFKI 1026
...::.||||||||.||||.:|.|||:||||.::||||||||||.|..:|.||:|||:||||.|:
Frog 1109 KQYKKNLNGILADETGLGKNVQVIALMAHLASSEGNWGPHLIVVRSCKILKWELEFKRWCPGLKV 1173
Fly 1027 LTYYGSQKERKLKRVGWTKPNAFHVCITSYKLVVQDQQSFRRKKWKYLILDEAQNIKNFKSQRWQ 1091
|.|:|.|:|.:.||..|.:||:|:|||||||.:.:..|:|.:|:||||:|||...|||...:.|.
Frog 1174 LLYFGKQRELRKKRQKWDEPNSFNVCITSYKHLFKSHQAFMKKRWKYLVLDEVHQIKNMTEKHWD 1238
Fly 1092 LLLNFSTERRLLLTGTPLQNDLMELWSLMHFLMPYVFSSHREFKEWFSNPMTGMIEGNMEYNETL 1156
.:.|..:..||||..|||.|...:.|:::|||:|.:...:.|| |:....|.|.|....|
Frog 1239 AVFNLPSHNRLLLRDTPLMNTWRDHWTMVHFLIPGLSQPYLEF------PLKISTEENQENCHKL 1297
Fly 1157 ITRLHKVIRPFLLRRLKKEVEKQMPKKYEHVITCRLSNRQRYLYEDFMSRAKTRETLQTGNLLSV 1221
...||:.:|||:|||.||:||||:.||||||:.|||||||:.||||.:.:..|::.|:.|:.:||
Frog 1298 FITLHRTVRPFILRRSKKDVEKQLTKKYEHVLKCRLSNRQKALYEDVILQPGTQDALKGGHFVSV 1362
Fly 1222 INVLMQLRKVCNHPNMFEARPTISPFQMDGITFHTPRLVCDIMEYDPFTQINLETLNLLLLHLEQ 1286
::|||||:::||||::.:.||..|.|..:.:.:.|..|:..::|.||:...::...: |..||.
Frog 1363 LHVLMQLQRICNHPDLVDPRPEHSSFVCETLQYRTASLILQVLEKDPWKITDMSLFD--LFGLED 1425
Fly 1287 TMTAYVSHKSRLLAPPRKLIEDIDTAPLPAPRCPNGKYRFHIRVRSAELAQRIKLNAVKVGAS-- 1349
.:|.|...........||.:|:|..:|..||| |. .::::.:.|.|.::......|.:
Frog 1426 KITRYEVQTLPGQKVTRKQMEEIYASPESAPR-PT-----PVKIKPSRLFQPVQYGQKPEGRTVT 1484
Fly 1350 ----PAMRL--------------------------EGSKIMPMRNLLPSGRVLKRVSASINPVNM 1384
||.|: :|..::.:..|..||....|::....||.:
Frog 1485 FSNVPASRMVTTTTATVTQQGQARGRSPVTTASCNQGGDVVKIAQLAASGGTQGRIAQPKTPVTL 1549
Fly 1385 ALKPVVINSVVTTTSS---STTASSPTGALSVLSNSKLLGARSQI-NAPTPAKVAKTMQDGKPFF 1445
..: .:..|.:.| ..||..|. :|.|:..|| :|| |:|
Frog 1550 QFQ----GNTFTLSQSQLRQLTAGQPL---------QLQGSVLQIVSAP-----------GQP-- 1588
Fly 1446 YLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTASTTSGQQLIRDPIVKDLATHVKSTVQKQS 1510
||.| .|..:..| ...|.....|....|.|| |......|..:|.:..::
Frog 1589 YLRP------PGQMIMQT--------VPQSGAIQNAINALGNQL---PAGMSCVTSAQSGIPGRT 1636
Fly 1511 I-ANGKTEPEEETEAEDPY-KVQELIQMRKEQRLAALKRMAMINRRRTDATPIYGEDCREAIQ-R 1572
: .:|..:|....::...: ..||..:.::......|.|:...|.|.....|:||.|...... .
Frog 1637 LMPHGCGDPGAALKSSSSFTPAQEFAEEKQRLMRECLDRLFSSNERNCGRAPVYGADLLSICSLN 1701
Fly 1573 CMQATRSLKRSTWQTRGYANCCTAMAHRNGWS--LNHLLKSFEERCAD-LKPVFAN--FVIYVPS 1632
...|..|:..|.|...|.|||..:....:..| |.||:.| .|.| ....|.| .:..|||
Frog 1702 AAGAEPSISGSQWGWAGSANCLRSSNLLDDTSDPLRHLILS---PCQDKATQEFLNKRTLCVVPS 1763
Fly 1633 V-CAPRIRRYVQNLSSTH----WQHEQRIENIVDQALRPKLA-LLHPIISEMT---TKFPDPRLI 1688
| .||.: |:..| :.|.. |::...|:.::| .||.::.:.: .:|||.|||
Frog 1764 VIAAPPV------LTMPHPPPRYTHSM---NLLRDGLKEQVAPHLHHLLRQTSPHCMQFPDLRLI 1819
Fly 1689 QYDCGKLQTMDRLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHGHIYLRLDGSTRVEQRQILME 1753
|:|.|||..:..|||:|:..|.|||||:||..|||:||.||::|...:||:|.....:|...||:
Frog 1820 QWDSGKLDALAVLLRKLRSEGRRVLIFSQMLLMLDILELFLDFHALTFLRIDEFANYDQCYDLMK 1884
Fly 1754 RFNGDKRIFCFILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVS 1818
.||.|.||||.::||.|..:|:....|:|.||||||.||.||::||..|.|||:|:|||||||||
Frog 1885 SFNQDPRIFCLLISTHSHSLGVPYVEANTAIFYDSDLNPVMDSRAQAWCERIGRTKDVHIYRLVS 1949
Fly 1819 ERTIEVNILKKANQKRMLSDMAIEGGNFTTTYFKSSTIKDLFTMEQSEQDESSQEKSENKDRIVA 1883
..:||..:||... |.::.::|.:|.:|:..:....||.:||.:.....|....||:|.
Frog 1950 ANSIEEKLLKNGT-KDLIREVAAQGNDFSMAFLTQQTIHELFELYSPLDDTGFGEKAEE------ 2007
Fly 1884 TTTLSDTPSTVVETEKQSLRAFEHALAAAED--EQDVQATK-TAKAEVAADLAEFDENIPIATED 1945
...||..||.......:..:.|..||.:.|: ||:.:..| .||...|.|..
Frog 2008 FIMLSQEPSQTETIATKFAKPFIEALKSIENGAEQEEEFLKGDAKKNFAVDSC------------ 2060
Fly 1946 PNAEGGPQVELSKADLEMQNLVKQLSPIERYAMRFVEE------TGAAWTAEQLRAAEAELEAQK 2004
...:|.|:. :|:..:|:||:|||:||:.::|| .|.|...|||::. |
Frog 2061 -----CHSIEASEL-MELAAVVEQLTPIEKYALNYLEEFYTSSAKGKAEIIEQLKST-------K 2112
Fly 2005 REWEANRLAAMHKEEELLKQETEAEEMLTYSRKDSSNQVWI---SRNTMEQMPMWCPPTPPQDND 2066
.:||...|......|:.:..|...|::|||:|:|:.|:.:| .....|.||:|.||||||| :
Frog 2113 TKWEVQNLKETKDWEDEMVLEESGEDLLTYTREDAYNKEFIYDSPDGQTEIMPIWTPPTPPQD-E 2176
Fly 2067 NDIYIDYSLSFMYELEPIAETDLPPVYVRKEHKRSRTDAGYDGSRRPNKMRREDNYVPPRSLFDR 2131
||||||..:..||:..||.|:.|||||||||.||.:||.|..| |..|.|..::.|||||||||
Frog 2177 NDIYIDSVMCLMYDSNPIPESKLPPVYVRKERKRHKTDPGAAG--RKKKQRHGESVVPPRSLFDR 2239
Fly 2132 PTPQLARLRRELKSQRFRGSFKPNMPIPGLKPQLPT--KPLTE--PEAMAEWCVFEDMAILHVLV 2192
.||.:.::|||.|.|:.....|..... .|| ||| ||.|| |: ..||.:.||.|:|..:.
Frog 2240 ATPGMLKVRREGKEQKKNILLKQQTQF--AKP-LPTLVKPATESGPD-NPEWLISEDWALLQAVK 2300
Fly 2193 NLQGLPCSLMLLSPGQTPNWDLVSEMVNFCSKTYRSARQCRWRYETHIQPREEGKVVESPKKQKK 2257
:|..||.:|.::||..||||||||::||.||:.|||::|||.|||..|.||||||::.....:||
Frog 2301 HLLELPLNLTVVSPAHTPNWDLVSDVVNSCSRIYRSSKQCRSRYENVIIPREEGKLMFEANPKKK 2365
Fly 2258 LKPTLRTEYLKSPLRYLRTTQLYVSDNNASFYKTMRSRFDSIKTAYLKKAPPPKRQFSA-PSLMN 2321
.|...:|: ..|.|||:|:|..|...:..:...:||:.:|....|::||.|..... |...|
Frog 2366 TKSIYKTK----NSRPLRTSQIYAQDEGVTHTQLYTNRFELMKMTAGKRSPPIKPLLGMNPFQKN 2426
Fly 2322 PKHMEVLQEFGILNYDQPVSPQNIAAMKANKIREKQRG----QQMSQPPVGVGVVQQMQQQSQQQ 2382
|||..||.|.|| |||:|:.|..:|:::|.:|.::::. ...:|...|....||.||..||.
Frog 2427 PKHASVLAESGI-NYDKPLPPIQVASLRAERIAKEKKALVEQHHRAQQQTGSQTAQQPQQNGQQV 2490
Fly 2383 QQPAPPPLPQQQQPQQVVQQVQQQQQQQQQQQQQQVVQQQLPTVSNVQQTLPVQQTVELVQQQPT 2447
..|... |.|.|||||| .|||:||..|.|......:|. |..|.....|
Frog 2491 SSPVVQ--PAQAQPQQVV--------------PQQVIQQSQPVVPTATSAVPA--TAVLAGAIKT 2537
Fly 2448 TTTTVAVPAAGGQLQQLQIQHLTSSNVSPGQQTAILLHQPQQQLRTHPGQGGQSNTQQLVKTIVG 2512
..|..::.||. .|.|| :|.|:.|
Frog 2538 AVTGASIQAAA-----------VSGNV-------------------------------IVNTVAG 2560
Fly 2513 TSSSLTAGQLQQLAQQSAVASGGQSSVSVVLTTPVQTLPSVVQPQ------IGSGAQIVSISSQ- 2570
..|:......::|| |.|..| .||.|..: |.||..| ..:.|::|:|::.
Frog 2561 VPSATFQPINKRLA--SPVIPG-------TLTAPSGS-PQVVHTQQRAAAAAAAPAEMVTIATNQ 2615
Fly 2571 ----TLPVNSSPQLGSIV-------QTQSLPQVVSVSTLPTVGTVLTTTANQP-------QQQHQ 2617
..||.. |::| |||:.|.|..|:|..|.|..|.:.:..| |||..
Frog 2616 GVRAVTPVTG----GAVVCSSITPAQTQTRPIVTQVTTATTAGVQLASKSITPAQLQMLRQQQAA 2676
Fly 2618 TTAVTTLNT-TMLRGQ-RIVSTAAGNTL-----------QQRTTAGGQSIVSMPNLGQGASPSQF 2669
...|..:.. |...|| :.|...:...| ||.|.|..|...|.| |:|.|.
Frog 2677 QVQVPQIQAQTQSPGQIKAVGKISQEQLLKLQKQKMQLPQQTTQATAQQSQSAP-----AAPVQG 2736
Fly 2670 QTQLRLAAVPTSPATQTTQLVTTKGIPVSALQQGGKTTVIPVTQQSGGAHIQLYRQRSLKVLQTT 2734
|.|.: .|....||.||.. |||.:.|...|...| |::|:.| |...|..
Frog 2737 QQQPQ----QTQAQQQTQQLAA-----VSAPRAGAVLTGATV------ANLQVAR---LLQAQGQ 2783
Fly 2735 TQAVPSGSAGATGATANLVQAGGTIIQASNMATHVTSQKVAVSGMP---GTSTTVQAGNVVSSVQ 2796
.||.| |.||.:..|...::.|...:..||:..|.|:|:. |.:.....|..|.:..
Frog 2784 IQAQP-------GQTAQVTLAKPPVVSAVVSSAGVTTLPVTVAGISVAIGQNQKAAGGQAVVAQP 2841
Fly 2797 MHGQARTQFIKQMAAGKQQLQRQVVSADGTTTTTAAGDMLLVKRHNILAAQKAQQASGALFTTTT 2861
:: ::|:...|||.|:.:.| .||.....|::..|.|.|.|.|.
Frog 2842 LN-------VQQLLKLKQQQQKALQS-------QAATGQAAVQQPKITAPQVAVQT--------- 2883
Fly 2862 GQQQQQQQQQGQLPVAGQPQQVTQHQIASLVKASTAAAASGSSVNAGGVTVSATNPTVQAGSVNM 2926
|||||.||||| |.||...:.....:|....|| |..||
Frog 2884 -QQQQQPQQQGQ-----QQQQKMTYTAQPAIKTQFLAA-----------------PINQA----- 2920
Fly 2927 TLPQLKPGSQIKVTMPNQMRHLQMQQQLTMPRKISRMTQLVSASGQPTATNIITTTGPQQQQQGV 2991
|..||:| |:|.|: :::::.|:| |||..|
Frog 2921 ---QKSPGAQ------------QVQGQI----QVAKLPQVV------------------QQQAAV 2948
Fly 2992 TVSGGGTLPTVASQQQQQQHQQKVGGGNSVQAQLLHIQNTKGLSNSVTMQQIQQVMRSGQQGTLA 3056
|.:....:|.:....||.|.| :||:.|
Frog 2949 TQAAVANIPQMVPSSQQVQPQ------------------------TVTLSQ-------------- 2975
Fly 3057 TTNLVLGKTSVGRVIPVSVASQANQRQTIQVVSAASAQALAAGNLRTHVAGPSIASTLKVAAPGS 3121
|:.|.|:|.:||:.| ||
Frog 2976 -------------------ATAAGQQQQVQVLPA-----------------------------GS 2992
Fly 3122 AGGQTTQQTLIAALQHNQRQNASPVRLQTTAGGNLLAVVQQQQQQQHTSIAGPTAGPAEVMTITQ 3186
|..|..||.:: |||||..|.||.....| ::.|
Frog 2993 AAAQVVQQKMV------------------------------QQQQQVVSSAGAQQIQA---SVNQ 3024
Fly 3187 TTTTLPTVGSLQQQQQQQQQQGGISQPTTQ 3216
:|| |.:|:...|.||.:.| :..||.:
Frog 3025 STT--PALGANDTQAQQAKLQ--VRTPTVR 3050
| 
