Protein Alignment dom and chd9

DIOPT Version :10

• Sequence 1: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Sequence 2: XP_031756017.1
• Gene: chd9 / 733830
• XenbaseID: XB-GENE-1217623
• Length: 2891
• Species: Xenopus tropicalis
• Alignment Length: 3507
• Identity: 645/3507 - (18%)
• Similarity: 1065/3507 - (30%)
• Gaps: 1357/3507 - (38%)

  Fly   283 GIGTGATKGAPLDGNISNSTVKTNTQSQVPSKIGSFTESTPAATESNSSTTVPGTATSGAATSTS 347
            |.|.....|:|:.|:        .|.:.:||:.||     |.....:|.|.   ..:.|..|...
 Frog   110 GSGIFPEDGSPMWGH--------QTSTSIPSQNGS-----PFHQHGHSQTI---QQSKGYVTHDD 158

  Fly   348 ATSAEAS----------------------GNVLAVEAEIKI-------PAVGATPVAISTKLPAA 383
            .|..:|:                      .|.:.|...:.:       |.:|.|..: ...||
 Frog   159 FTLYQANEQQTPQCPINSISVGPETLNQPKNFMDVNVSVPLSIGNAQQPQLGNTATS-QQSLP-- 220

  Fly   384 VVQLTQQG----HIPGRPLGGRHGMVFGQIPAPPAAVGNPSVPLVPGGTPLLPCNTSAG---STA 441
            |.|.:|..    |..|.|||.:|...| :..:|                .|.||:..|.   ||.
 Frog   221 VQQFSQPTAATLHFCGNPLGVQHESTF-ESHSP----------------TLTPCSVDATQPFSTQ 268

  Fly   442 LRRPQGQNNAS-------SGSAAASGGG-------GSLTP-TPLYTGNGPAALG----GSGGLTP 487
            ......|.|.:       :|::|.|..|       |.:.| ..|::.|......    |:...|.
 Frog   269 YSFSNNQLNHTTPSLPELTGNSAFSDIGTKHETNQGMMNPNAELHSNNFQVVQSSHAHGNFNRTK 333

  Fly   488 GTPTSGSLLSPALGGGSGTP----NSAAQEFSFKAKQEVYVM------QRISELQREGLWTERRL 542
            .:|.:.:...|   .||.|.    |...:...|...::..:.      :..|.|..|.|..|..|
 Frog   334 MSPETINFTHP---DGSSTQMRHFNDHIENNGFSPLEDTLLQHVDAQTEHFSGLDPEDLLQEDLL 395

  Fly   543 PKLQEPSRPKAHWDYLLEEMVWLAADFAQERKWKKNAAKKCAKMVQKYFQD-KATAAQRAEKAQE 606
            ....|||                   |:||      .|...:.:::  .|| |.|.|:
 Frog   396 KHFDEPS-------------------FSQE------DANSSSNILE--HQDMKITFAR------- 426

  Fly   607 LQLKRVASFIAREVKSF---WSNVEKLVEYKHQTKIEEKRKQALDQHLSFIVDQTEKFSQQLVEG 668
            .|:|.....:..:..:.   |    .|.:..|....|||      ||.:|   |.:..|.:..:|
 Frog   427 TQIKLQNDILGSQPHNNHHPW----HLSDSNHHLPQEEK------QHCTF---QGKPPSSKKTDG 478

  Fly   669 MN--KSVADTPSLNSSRLTSPKRESDDDFRPESGSEDDEETIAKAEE------------------ 713
            ..  :.:|:. .:.|:....||::.|.:.:.|..:....|.||||:|
 Frog   479 FRAFQRLANI-KVRSASDKRPKKKVDTESKQEKANRIISEAIAKAKERGERNIPRVMSPENFPSV 542

  Fly   714 --DAADVKEEVTALAKESEMDFDDFLNDLPPGYLENRDKLMK------EEQSSAIKTETPDDSDD 770
              :..|.|......:|..|.:.......| ...|:.:.|:.|      .:|..  |.|:.||..|
 Frog   543 SSEGKDEKRGRKGKSKPKEKEGKKTKAGL-SSELKEKKKIGKLIITLGRKQKR--KMESSDDVSD 604

  Fly   771 SEFEAKEASDDD-------------ENTISKQEEAEQEIDHKKEIDELEADNDLSVEQLLAKYKS 822
            |:...:..:|:|             :.|.|.:..:.:::..||.::::|           .|...
 Frog   605 SDRAPRVHNDEDLQEFAWRTDHLHQDQTGSMKRRSNRQVKRKKYVEDVE-----------GKQSE 658

  Fly   823 EQPPS---PKRR--KLAPRDP-----ELDSDDDSTAVD--------STEESEDAATEDEEDLSTV 869
            ::|.:   ||:.  .|....|     |..|::|:..||        ..|.|.....|.||.....
 Frog   659 DEPKANVKPKKNSTSLPVEQPLQLFVENPSEEDAAIVDKILASRIAKKETSSGTFVEVEEYYVKY 723

  Fly   870 KTDT-------------------------------------DMEEQDEQEDGLK-------SLMA 890
            |..:                                     ||||:....|.::       ||..
 Frog   724 KNYSYLHCEWATEQQLLKDKRIHQKIKRFKIRQAQRAHFFADMEEELFNSDYIEVDRVLEVSLCQ 788

  Fly   891 DADATS----------GAAGSGSTAGASGNKDDMLNDAAALAESLQPKGNTLSSTNVVTPVP--- 942
            |.|...          ......||.....:.|....|.....::|:|     .:..|..|.|
 Frog   789 DKDTGEPVIYYLVKWCSLPYEDSTWELKEDVDQAKIDEFEQLQALKP-----DARRVERPPPNSW 848

  Fly   943 --------FLLKHSLREYQHIGLDWLVTMNERKLNGILADEMGLGKTIQTIALLAHLACAKGNWG 999
                    :.:.:.|||||..||:||:.....:.|.|||||||||||||:|..|..:...:.. |
 Frog   849 KKINQSREYKIGNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFLQEIYLNRIP-G 912

  Fly  1000 PHLIVVPSSVMLNWEMEFKKWCPGFKILTYYGSQKERKL------------KRVGWTKPNAFHVC 1052
            |.||:.|.|.:.|||.||:.| ....::.|:||...|::            .|:.|.. ..||..
 Frog   913 PFLIIAPLSTIANWEREFRTW-TDLNVVVYHGSMISRQMIQQYEMYFRDSQGRIIWGS-YKFHAI 975

  Fly  1053 ITSYKLVVQDQQSFRRKKWKYLILDEAQNIKNFKSQRWQLLLNFSTERRLLLTGTPLQNDLMELW 1117
            ||::::::.........:|:.:|.|||..:||...:..:.|...:.|.::|||||||||.:.||:
 Frog   976 ITTFEMILGGCPELNAIEWRCVIFDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTPLQNTVEELF 1040

  Fly  1118 SLMHFLMPYVFSSHREFKEWFSNPMTGMIEGNMEYNETLITRLHKVIRPFLLRRLKKEVEKQMPK 1182
            ||:|||.|..|.|...|.:.|.:..|          |..:.:|..:::|.:|||||::|||::..
 Frog  1041 SLLHFLEPQRFPSESTFMQEFGDLKT----------EEQVQKLQAILKPMMLRRLKEDVEKKLAP 1095

  Fly  1183 KYEHVITCRLSNRQRYLYEDFMSRAKTRETLQTG----NLLSVINVLMQLRKVCNHPNMFEARPT 1243
            |.|.:|...|:|.|:..|...:.  |....|..|    |:.:::|.:|:|||.||||.:
 Frog  1096 KEETIIEVELTNIQKKYYRAILE--KNFAFLSKGAGQANVPNLVNTMMELRKCCNHPYL------ 1152

  Fly  1244 ISPFQMDGITFHTPRLVCDIMEYDPFTQINLETLNLLLLHLEQTMTAYVSHKSRLLAPPRKLIED 1308
                                                                             
 Frog  1153 ----------------------------------------------------------------- 1152

  Fly  1309 IDTAPLPAPRCPNGKYRFHIRVRSAELAQRIKLNAVKVGASPAMRLEGSKIMPMRNLLPSGRVLK 1373
                                 ::.||
 Frog  1153 ---------------------IKGAE--------------------------------------- 1157

  Fly  1374 RVSASINPVNMALKPVVINSVVTTTSSSTTASSPTGALSVLSNSKLLGARSQINAPTPAKVAKTM 1438
                                                       .|:||
 Frog  1158 -------------------------------------------EKILG----------------- 1162

  Fly  1439 QDGKPFFYLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTASTTSGQQLIRDPIVKDLATHVK 1503
                                                                             
 Frog  1163 ----------------------------------------------------------------- 1162

  Fly  1504 STVQKQSIANGKTEPEEETEAEDPYKVQELIQMRKEQRLAALKRMAMINRRRTDATPIYGEDCRE 1568
                                                                         :.||
 Frog  1163 -------------------------------------------------------------EFRE 1166

  Fly  1569 AIQRCMQATRSLKRSTWQTRGYANCCTAMAHRNGWSLNHLLKSFEERCADLKPVFANFVIYVPSV 1633
                                                      ::.:..||.
 Frog  1167 ------------------------------------------TYNQMAADF-------------- 1175

  Fly  1634 CAPRIRRYVQNLSSTHWQHEQRIENIVDQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKLQTM 1698
                   |:|                                          .:|| ..|||..:
 Frog  1176 -------YLQ------------------------------------------AMIQ-SAGKLVLI 1190

  Fly  1699 DRLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHGHIYLRLDGSTRVEQRQILMERFN-GDKRIF 1762
            |:||.::|..||:||||:||.:.||:||.:|.:..::|.|:||..|...||..::||: .|...|
 Frog  1191 DKLLPKMKAGGHKVLIFSQMVRCLDILEDYLMHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRF 1255

  Fly  1763 CFILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSERTIEVNIL 1827
            .|:|.||:||:|||||.|||.|.:||||||..|.|||.|||||||.:.|.:|||::..:.|..:.
 Frog  1256 VFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLITRNSYEREMF 1320

  Fly  1828 KKANQKRMLSDMAIE---------GGNFTTTYFKSSTIKDL-----FTMEQSEQDESSQEKSENK 1878
            .:|:.|..|....::         ||   ........|:||     :.....|:||.|:...|:.
 Frog  1321 DRASLKLGLDKAVLQSMSGRENSVGG---IQQLSKKEIEDLLRRGAYGAIMDEEDEGSKFCEEDI 1382

  Fly  1879 DRIVATTTLSDTPSTVVETEKQSLRAFEHALAAAEDEQDVQATK-------TAKAEVAADLAEFD 1936
            |:|:...|.:.|    :|:|.:.....:.:..|:.:..|:....       ..|||:..|.....
 Frog  1383 DQILQRRTKTIT----IESEGRGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAEIDIDSVSGR 1443

  Fly  1937 ENIPI-------------ATEDPNAEGGPQVELSKADLEMQNLVKQLSPIER------------- 1975
            .::.|             ||:|..|      |||:|:.|.::..|...|.:|
 Frog  1444 NSLVIDTPRIRKQTRPFSATKDELA------ELSEAESEGEDKPKLRRPYDRANGYGRTECFRVE 1502

  Fly  1976 ----------------------------------------------------YAMRFVEETGAAW 1988
                                                                :....:..|....
 Frog  1503 KNLLVYGWGRWRDILSHGRFKRQLNEQDVEIICRALLAYCLVHYRGDEKIKSFIWDLITPTEDGR 1567

  Fly  1989 TAE------------------QLRAAEAELEAQKREWEANRLAAMHKEEELLKQETEAE------ 2029
            |.|                  :::...:..:..|.||     ...|..|.||:.:...:
 Frog  1568 TRELQNHLGLSAPVPRGRKGKKVKTQTSTFDIHKAEW-----LRKHNPEHLLQDDGYKKHLKHHC 1627

  Fly  2030 -------EMLTYSRKD---------------SSNQVWISRNTMEQMPM-WCPPTPPQ-------- 2063
                   .||.|.|::               |...:|:......::|: |......:
 Frog  1628 NKVLLRVRMLYYLRQEVIGVYCQKVLDGVASSEIDLWVPEPDHSELPVDWWDTEADKSLLIGVFK 1692

  Fly  2064 ---DNDNDIYIDYSLSFMYELEPIAETDLPPVYVRK-------------EHKRSRT---DAGYDG 2109
               :..|.|..|.:|.|   ||...:.|...|...:             |:|.:.|   |...|.
 Frog  1693 HGYEKYNTIRADPALCF---LERAGKPDEKAVAAEQRANDFIDGDVEDPEYKPAPTLFKDDMKDD 1754

  Fly  2110 SRRPNKMRREDN----------YVPPRSLFDRPTPQLARL----RRELKSQRFRGSFKPNMPIPG 2160
            ...|..:...|.          |.|.:|..   |.:|.||    :|..|.::.: ...|..|:..
 Frog  1755 DASPGDLIIADGDGQIMDGDKVYWPTQSAL---TTRLRRLVTAFQRTSKCKQVQ-LVTPVFPVQA 1815

  Fly  2161 LKPQLPTKPLTEPEAMA-----------------------------------EWCVFEDMAILHV 2190
            .....|.:..|....||                                   :|..|..||.||.
 Frog  1816 AATHAPNEEATLNPKMAAKIERQQRWTRREEADFYRVVSTFGVVFDPGRGQFDWTKFRAMARLHK 1880

  Fly  2191 LVNLQGLP---------CSLMLLSPGQTPNWDLVSEMVNFCSKTYRSARQCRWRYETHIQPREEG 2246
            ..: :.|.         |..:...|.:.   :.|...::....|...|.:..:|.|...:.||:
 Frog  1881 KTD-ESLEKYLYAFIAMCRRVCRLPSRD---EFVDSSISIQPITEERASRTLYRIELLRKVREQ- 1940

  Fly  2247 KVVESPKKQKKLK-----PTL-----------------------RTEYLKSPLRYLRTTQLYVSD 2283
             .:..|:..::||     |.|                       ||:|     ..||..:|
 Frog  1941 -ALRHPQLFERLKLCQPNPDLPVWWECGTHDRDLLIGAAKHGVSRTDY-----HILRDPEL---- 1995

  Fly  2284 NNASFYKTMRSRFDSIKTAYLKKAPPPKRQFSAPSLMNPKHMEVLQEFGILNYDQPVSPQNIAAM 2348
               ||..|.::...|..|:            |.|.|..|.|:.: ..|.:.::.:   .|::...
 Frog  1996 ---SFMVTQKNYSQSKGTS------------STPLLAIPNHLSI-TAFPLHSHSK---VQDVKGF 2041

  Fly  2349 KANKIREKQRGQQMSQPPVGVGVVQQMQQQSQQQQQPAPPPLPQQQQPQQVVQQVQQQQQQQQQQ 2413
            ..:.||.|                                    ::..::.:...:::....::.
 Frog  2042 TNDDIRVK------------------------------------EEALKEDILTSEEESASSERL 2070

  Fly  2414 QQQQVVQQQLPTVSNV----QQTLPVQQTVELVQQQPTTTTTVAVPAAGGQLQQLQIQHLTSSNV 2474
            :.::.::...||:..|    :|...|:  :|..::.....|....|....:.|::......||:.
 Frog  2071 KARRKIESLNPTIGPVFHAKEQKAVVK--IETNRRMVAARTEPLTPNLTSKKQRISKHESASSSD 2133

  Fly  2475 SPGQQTAILLHQPQQQLRT------HPGQGGQSNTQQLVKTIVGTSSSLTAGQLQQL-------A 2526
            |.................|      |.|....|::.....:...:|||.::......       |
 Frog  2134 SDSDSNRSSCSSRSSSSSTSSSSCSHSGSSSSSSSSSSCSSSTSSSSSSSSSSTSSSEDSDDGDA 2198

  Fly  2527 QQSA-----VASGGQSSVSVVLTTPVQTLPSVVQPQIGSGAQIVSISSQTLPVNSSPQLGS---- 2582
            |:||     |.:..:.||:.|.|...:|..|.   |:.:|..           |||..|..
 Frog  2199 QKSAESVPHVKTYDEESVASVSTLQDETQDSF---QMDNGTP-----------NSSCFLPGGYML 2249

  Fly  2583 -----------IVQTQSLPQVVSVSTLPTVGTVLTTTANQPQQQHQTTAVTTLNTTMLRGQRIVS 2636
                       |.:..|:.|.|.....||.           ::.::.|:|.:...|.|......:
 Frog  2250 AGAHWPKDRVMINRLDSICQAVLKGKWPTT-----------RRNYEATSVASFYATKLLDSPGAA 2303

  Fly  2637 TAAGNTLQQRTTAGGQSIVSMPNLGQGASPSQFQTQLRLAAVPTS-PATQTTQLVTTKGIPVSAL 2700
            |......||..:.  .|:...|:            .|:::.|... |..:.|..:..:|......
 Frog  2304 TEYSEAGQQAPSC--LSVKEEPD------------HLQMSKVKKHVPEKEFTVKINDEGGLKLTF 2354

  Fly  2701 QQGGKTTVIPVTQQSGGAHIQLYRQRSLKVLQTTTQA-----VPSGSAGATGATANLVQAGGTI- 2759
            |:.|.....|:..:.|... |.|..| |:.||..:::     ..|.:|..|..|::.|...|.:
 Frog  2355 QKQGVPQKRPLDCEEGLGQ-QQYLAR-LQDLQNASESSLVNFPKSSTASGTLCTSSAVYTNGALP 2417

  Fly  2760 -----------------------IQASNMATHVTSQKVAVSGMPG------TSTTVQ----AGNV 2791
                                   ...:.|..||:....:....|.      :||.||    |.|.
 Frog  2418 GTQPVNKKRRGRRKNVEGVDHLFTNQNKMLNHVSEVLASTFPQPAPCSQALSSTKVQWVQDADNP 2482

  Fly  2792 VSSVQMHGQARTQ-------------------FIKQMAA-----------GKQQLQR-QVVSADG 2825
            |..:.:....|..                   :::.:.|           .||:..| :..|...
 Frog  2483 VPVINLKDGTRLAGDDAPKRKDLENWLKEHPGYVEDLGAFIPRVQFHDGRPKQKRHRCRNPSKLD 2547

  Fly  2826 TTTTTAAGDMLLVKRHNILAAQKAQQASGALFTT---------------TTGQQQQQQQQQGQLP 2875
            ..:.|....:.|:.|.|      |::..||....               ...:.....:|.|.||
 Frog  2548 VNSLTGEERVQLINRRN------ARKVGGAFAPPLKDLCKFLKENPEYGVAPEWGDVVKQSGFLP 2606

  Fly  2876 VAGQPQQVTQHQIASLV-------KASTAAAASGSSVNAGGVTVSATNPTVQAGSVNMTL-PQLK 2932
            .:...:.:|...:...|       |:.||.||..::|             ..:.|||..| ..|.
 Frog  2607 DSMFDRILTGPVVREEVSRRGRRPKSETAKAAVATTV-------------ANSDSVNQLLGNSLI 2658

  Fly  2933 PGSQIKVTMPNQMRHLQMQQQLTMPRKISRMTQLVSASGQPTATNIITTTGPQQQQQGVTVSGGG 2997
            ||..:......| ::.|..|.|.:...:..:...:||||..:..  :|...|      :.:|...
 Frog  2659 PGVDLSSYQALQ-QNFQSLQSLQLTAGLIGLPAGLSASGGDSKN--LTAMLP------MLLSSMA 2714

  Fly  2998 TLPTVASQQQQQQHQQKVGGGNSVQAQLLHIQNTKGLSNSVTMQQIQQVMRSGQQGTLATTNLVL 3062
            .||::            :|.|        |:.|           :..::...|::.. .|:.|..
 Frog  2715 GLPSL------------LGMG--------HLLN-----------KSSELSTDGKEKN-CTSGLKE 2747

  Fly  3063 GKTSVGRVIPVSVASQANQRQTIQVVSAASAQALAAGNLRTH-VAGPSIASTLKVAAPG-----S 3121
            |..:..|.:..| ..:|||..:  ..|.::..|:.||:|..: :..|:|.....:..||     .
 Frog  2748 GDGNKERTVSPS-DDKANQNTS--PPSTSTGMAVTAGSLALNPLLLPNIIYPGMLLTPGLNLHIP 2809

  Fly  3122 AGGQTTQQTLIAALQHNQR-QNAS-----PVRLQTTAGGNLLAVVQQQQQQQHTSIAGPTAG 3177
            |..|:....:..|...|.| ||..     ||..|....|..|....:....:.:..|.|::|
 Frog  2810 AVPQSNLYDVQNASNENCRAQNTDVTAELPVPSQEEKPGKELCSQNENSTDEGSEKADPSSG 2871

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dom	NP_001286676.1	HSA	543..614	CDD:214727	14/71 (20%)
		HepA	692..>1235	CDD:440319	172/680 (25%)
		DEXQc_SRCAP	949..1171	CDD:350761	82/233 (35%)
		SF2_C_SNF	1685..1817	CDD:350180	68/132 (52%)
		DISARM_DrmD_b	<1702..>1936	CDD:468472	88/255 (35%)
		HEC1	<1858..>2031	CDD:444066	42/293 (14%)
		SP1-4_N	2486..>2819	CDD:425404	76/436 (17%)
chd9	XP_031756017.1	CDC27	<469..675	CDD:462819	40/220 (18%)
		CD1_tandem_CHD5-9_like	689..753	CDD:349315	9/63 (14%)
		CD2_tandem_CHD5-9_like	774..831	CDD:349310	9/56 (16%)
		PLN03142	859..>1488	CDD:215601	227/1079 (21%)
		BRK	2477..2518	CDD:462196	4/40 (10%)
		BRK	2552..2596	CDD:197800	7/49 (14%)