Protein Alignment dom and ino80

DIOPT Version :9

• Sequence 1: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Sequence 2: XP_009299103.1
• Gene: ino80 / 566768
• ZFINID: ZDB-GENE-041014-72
• Length: 1558
• Species: Danio rerio
• Alignment Length: 1654
• Identity: 433/1654 - (26%)
• Similarity: 681/1654 - (41%)
• Gaps: 395/1654 - (23%)

  Fly   448 QNNASSGSAAASGGGGSLTPTPLYTGNGPAALGGSGGLTPGTPTSGSLLSPALGGGS--GTPNSA 510
            ||.:|..|....|.|.||      ..:.|........::|...|..|    ...|.:  ||.|.|
Zfish    44 QNISSDDSDDGLGEGSSL------ASSNPLLAVKKDHISPEDETKDS----CRDGETECGTLNGA 98

  Fly   511 AQEFSFKAKQEVYVMQRISE---------------------------LQREGLWTERRLPKLQEP 548
            ..:.....|..:|...|:.:                           :.||.|....||.|....
Zfish    99 VLQEHKADKASLYNFSRLKKSRKWLKGILLSDDTTDSDSDSDDSDFTMTREELQDMLRLHKFTRL 163

  Fly   549 SRPKAHWDYLLEEMVWLAAD--------FAQER------KWKKNAAKKCAKMVQKYFQDKATAAQ 599
            .:.|.|.|..|:.....:..        :.|:|      |.|....|||...::|..:.|....:
Zfish   164 HQSKFHSDRELQHYQHYSTGLLSTHDPFYEQQRHLLGLKKKKIKEEKKCKAKLKKMKRKKKRGEE 228

  Fly   600 RAEKAQELQLKRVASFIAREVKSFWSNVEKL--VEYKHQTKIEEKRKQALDQHLSFIVDQTEKFS 662
            .:.:.::...|..|.|         |:...|  ::.||.| ||:...:.....|:....:..|..
Zfish   229 FSMEGRQHITKTFAKF---------SHDAPLPMIKKKHLT-IEQLNARRRKVWLTIAKKEIPKAF 283

  Fly   663 QQLVEGMNKSVADTPSLNSSRLTSPKRESDDDFRPESGSEDDEETIAKAEEDAADVKEEVTALAK 727
            :|.|...|..:.:...|....:...:|.:      ....::.:||:.:|..           |.|
Zfish   284 KQKVSARNFVLTNARKLAHQCMREVRRAA------IQAQKNCKETLPRARR-----------LTK 331

  Fly   728 ESEMDFDDFLNDLPPGYLENRDKLMKEEQSSAIKTETPDDSDDSEFEAKEASDDDENTISKQEEA 792
            |..:            |.:..:|:.||.:..|.|........|.|....:......|.:..|.|.
Zfish   332 EMLL------------YWKKYEKVEKEHRKRAEKEALEQRKLDEEMREAKRQQRKLNFLITQTEL 384

  Fly   793 EQEIDHKKEIDELEADNDLSVEQLLAKYKSEQPPSPKRRKLAPRDPELDSD-DDSTAVDSTEESE 856
            .......|:    .|..|.:.|::|             |||.....:...| .....|:.::|..
Zfish   385 YAHFMGGKQ----NAGGDCTQEEIL-------------RKLEDNSSQRQIDIGGGVMVNVSQEDY 432

  Fly   857 DAATEDEEDLSTVK-------TDTDMEEQDEQEDGLKSLMADADATSGAAGSGSTAGASGNKDDM 914
            |:.....:.|...|       ..|.:.:::.::....||.|       |:.|||..|.|.:   :
Zfish   433 DSDYYKSQALKNAKEAYQIHQARTRLFDEEAKDSRCASLHA-------ASMSGSGFGESYS---L 487

  Fly   915 LNDAAALAESLQPKGNTLSSTNVVTPVPFLLKHSLREYQHIGLDWLVTMNERKLNGILADEMGLG 979
            .|.:....|.:              |.|.:....|:.||..|::||..:.|:.:|||||||||||
Zfish   488 SNPSIQAGEDI--------------PQPTIFNGKLKGYQLKGMNWLANLYEQGINGILADEMGLG 538

  Fly   980 KTIQTIALLAHLACAKGNWGPHLIVVPSSVMLNWEMEFKKWCPGFKILTYYGSQKERKLKRVGWT 1044
            ||:|:||||||||..:..|||.||:.|:|.:.||..||.::.|.||:|.|:|:..:||:.|..|:
Zfish   539 KTVQSIALLAHLAERENIWGPFLIISPASTLNNWHQEFSRFVPKFKVLPYWGNPHDRKVIRKFWS 603

  Fly  1045 K-----PNA-FHVCITSYKLVVQDQQSFRRKKWKYLILDEAQNIKNFKSQRWQLLLNFSTERRLL 1103
            :     .|| |||.||||:|||||.:.|:|.||:|::|||||.:|:..|.||::||.|....|||
Zfish   604 QKTLYTQNAPFHVVITSYQLVVQDVKYFQRVKWQYMVLDEAQALKSSTSVRWKILLQFQCRNRLL 668

  Fly  1104 LTGTPLQNDLMELWSLMHFLMPYVFSSHREFKEWFSNPMTGMIEGNMEYNETLITRLHKVIRPFL 1168
            |||||:||.:.|||:|:||:||.:|.||.||.||||..:....|.....:|..::|||.:::||:
Zfish   669 LTGTPIQNTMAELWALLHFIMPTLFDSHEEFNEWFSKDIESHAENKSAIDENQLSRLHMILKPFM 733

  Fly  1169 LRRLKKEVEKQMPKKYEHVITCRLSNRQRYLYEDFMSRAKTRETLQT---------GNLLSVINV 1224
            |||:||:||.::..|.|.:..|:|::|||.||:...::....:.||:         ....|::|:
Zfish   734 LRRIKKDVENELSDKIEILTYCQLTSRQRLLYQALKNKISIEDLLQSSMGSAQQAHSTTSSLMNL 798

  Fly  1225 LMQLRKVCNHPNMFEARPTISPFQMDGITFHTPRLVCDIMEYDPFTQINLETLNLLLLHLEQTMT 1289
            :||.|||||||::||.:...|||.|....|        ||....|....|.|::.....|:||:.
Zfish   799 VMQFRKVCNHPDLFERQEIRSPFHMSLKPF--------IMSKFLFRHAILHTIDHGKTKLKQTLL 855

  Fly  1290 AYVS--HKSRLL--------APPRKLIEDIDTAPLPAPRCPNGKYRFHIRVRSAELAQ------R 1338
            :..|  |..:.|        |.....:..||.:|                   ||::.      .
Zfish   856 SPFSAQHIQQSLFHRKTDDEASSFSFLRFIDVSP-------------------AEMSNVMLQGTL 901

  Fly  1339 IKLNAVKVGASPAMRLEGSKIM---PMRNLLPSGRVLKRVSASINPVNMALKPVVINSVVTTTSS 1400
            ::..|:.:....|.||..|:..   .|..:...||:.|...:..:.:....:|....:|.::...
Zfish   902 VRWLALYLSFKSAYRLHHSRQWEEEKMSEVKGRGRLEKLCLSHRDLILWLNRPTSFPNVHSSPVL 966

  Fly  1401 STTASSPTGALSVLSNSKLLGARSQINAPTPAKVAKTMQDGKPFFYLTPATNSGAAGARLTLTSK 1465
            .....:.||:||:.....::.:|.     :..:..:..|..:|..:|            |.:|.:
Zfish   967 QDLVFTSTGSLSICHTDAVIHSRR-----SSTRTLRQCQPTQPPKFL------------LAVTPR 1014

  Fly  1466 TTASASTTTSRTTVTASTTSGQQLIRDPIVKDLATHVKSTVQKQSIANGKTEPEEETEAEDPYKV 1530
            .|   |....|.....|.....:|:||.         .|.:.||....|..|
Zfish  1015 VT---SVPLERYCADRSAEYEWRLMRDG---------GSLIAKQCFLYGSPE------------- 1054

  Fly  1531 QELIQMRKEQRLAALKRMAMINRRRTDATPIYGEDCREAIQRCMQATRSLKRSTWQTRGYANCCT 1595
                       ||                             |..|.||.........|    ..
Zfish  1055 -----------LA-----------------------------CAWAQRSQSFLPPNPGG----VM 1075

  Fly  1596 AMAHRNGWSLNHLLKSFEERCADLKPVFANFVIYVPSVCAPRIRRYVQNLSSTHWQHEQRIENIV 1660
            |:..|:|||                     |:
Zfish  1076 ALQQRHGWS---------------------FI--------------------------------- 1086

  Fly  1661 DQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKLQTMDRLLRQLKVNGHRVLIFTQMTKMLDVL 1725
                                :.||...:..|.|||.|:|.||.:||..||||||::|||:|:|:|
Zfish  1087 --------------------RIPDKESLITDSGKLHTLDLLLTRLKSQGHRVLIYSQMTRMIDLL 1131

  Fly  1726 EAFLNYHGHIYLRLDGSTRVEQRQILMERFNGDKRIFCFILSTRSGGVGINLTGADTVIFYDSDW 1790
            |.::.|..|.|:|||||:::.:|:.::..|.....||.|:||||:||:|||||.|||||||||||
Zfish  1132 EEYMVYRKHTYMRLDGSSKISERRDMVADFQSRTDIFVFLLSTRAGGLGINLTAADTVIFYDSDW 1196

  Fly  1791 NPTMDAQAQDRCHRIGQTRDVHIYRLVSERTIEVNILKKANQKRMLSDMAIEGGNFTTTYFKSST 1855
            |||:|.||.||.||:|||:.|.:|||:.:.|||..||::|.:|..:..|.|.||||.....|...
Zfish  1197 NPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEERILQRAKEKSEIQRMVISGGNFKPDTLKPKE 1261

  Fly  1856 IKDL----------FTMEQSEQ---DESS--QEKSENKDRIVATTTLSDTPSTVVETEKQSLRAF 1905
            :..|          ..:.|.|:   :|||  :|:...:::........|.|.:  :.:|:.:...
Zfish  1262 VVSLLLDDEELEKKLRLRQEEKRQLEESSKVKERKRKREKYAERKRKEDDPES--KRKKEGVNMV 1324

  Fly  1906 EHALAAAEDEQDVQATKTAKAEVAADLAEFDENIPIATEDPNAEGGPQVELS-KADLEMQNLVKQ 1969
            ...:.:|::     :..:|..|.:....:.|..||    .|.:|....:::| .::|:..::...
Zfish  1325 IPYVPSADN-----SNLSADGEDSFISVDMDSAIP----SPFSENYVSLQISLSSELQPSSIPAD 1380

  Fly  1970 LSPIERYAMRFVEETGAAWTAEQLRAAEA 1998
            .|..:...:  |:|..:  :|:|.||..:
Zfish  1381 ESSSDMLVI--VDEPVS--SAQQSRATNS 1405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dom	NP_001286676.1	HSA	543..614	CDD:214727	15/84 (18%)
		ASF1_hist_chap	<674..831	CDD:304562	24/156 (15%)
		FAM176	<824..>868	CDD:291517	8/44 (18%)
		SNF2_N	952..1238	CDD:278600	143/300 (48%)
		DEXDc	969..1108	CDD:238005	80/144 (56%)
		Helicase_C	1692..1806	CDD:278689	67/113 (59%)
ino80	XP_009299103.1	DBINO	263..392	CDD:290603	24/157 (15%)
		SNF2_N	511..812	CDD:278600	143/300 (48%)
		DEXDc	528..673	CDD:238005	80/144 (56%)
		Helicase_C	1098..1212	CDD:278689	67/113 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D188211at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010