|
Fly 1 MNEGNSAGGGH------EGL--------SPAPP-AVPDR--VTPHSTEISVAPANSTSTTVRAAG 48
:|..:..|.|| .|| ||..| ||.:| ..||| .|.:||.
Zfish 197 INLSSPPGSGHFVYQDGAGLATGTVHLTSPGTPGAVRERRLSQPHS-----QPGSSTV------- 249
Fly 49 SVGAALPATRHHQHIATQVKGIASSSSKQQKQLASAQLPVPLSPLPQQQQQTAEATAAAAAPAHS 113
||:.:.:||..:.|.. |:..:.||.|
Zfish 250 ----------HHKALPSQVPTLGSPG------------PITTTNLPPQ----------------- 275
Fly 114 NVSVSSSTIEASVLPPQAKRQRLDDNEDRTSAASIVGPAESS----NIVSSLLPASVASSSEVGG 174
.||.|:..:..|.. .::|| .|:||.|.|: .:.|::.|:|.:.|:...|
Zfish 276 ----ISSIIQGQLARPTM--------FEKTS-QSVVGVANSAAATFGVPSTIPPSSPSRSNSSQG 327
Fly 175 LSSTAL--------------------QDLNALKKRILQQKLQILRNLKERHLENVSEYFYLQN-G 218
|||.:| .::..|:|:.|:...:.:..|||...|.:.|.|:||: .
Zfish 328 LSSQSLTPTSMKKMQPKKLEEIAPSNPEVAQLRKQCLEHHGKKMEGLKEVFKEYLIELFFLQHLQ 392
Fly 219 GSMMDYPAWRKKTPTPQFISYSNANRIDQLIHEDKPSTSAAAAAAQNQKYTTQQTDSVESSLVSG 283
|:||||.|::||...|.| :|...|.:|....|::...|
Zfish 393 GNMMDYIAFKKKPCVPLF-TYLRQNDLDLEDEEEEEEQS-------------------------- 430
Fly 284 IGTGATKGAPLDGNISNSTVKTNTQSQVPSKIGSFTESTPAATESNSSTTVPGTATSGAATST-- 346
.:.|..||. |..|.|... ||.|. :|.:|...::..:|..
Zfish 431 -------------EVINDEVKV-----VTGKDGQTV--TPVAI----ATQLPPNVSAAFSTQQQF 471
Fly 347 SATSAEASGNVLAVEAEIKIPAVGATPVAIST-KLPAAVVQLTQQGHIPGRPLGGRHGMVFGQIP 410
...:..|||:: :.||.:.. |...|:.|..|... .|...|||||:| |.|
Zfish 472 QTHAGVASGSI-------------SNPVDMEAFKRQQAMAQADQAKR--SRMEVGRHGMIF-QHP 520
Fly 411 APPAAVGNPSVPL------VPGGTPLLPCNTSAGSTALRRPQGQNNASSGSAAASGGGGSL-TPT 468
| ...:|:|.||| ..||.|..|.....|.. ::.|.|.:.|.|....: ..|| ||.
Zfish 521 A-VTPLGSPGVPLQQLMPTAQGGMPPTPQTVQIGGQ--KQNQQQYDPSKGPPVQN--AASLHTPP 580
Fly 469 PLYTGNGPAA----------------------------LGGSGG--------------------- 484
|...|..|.| :.|:|.
Zfish 581 PQLPGRLPQAGLPLSLAQGQAMVVDQQATVTGGQLQVKVQGAGAVLAPVNPHAQLQAQLQQMQSG 645
Fly 485 -------------------------LTPG------------------------------------ 488
|.||
Zfish 646 LHLQMQQQQQMQQSVMQPGQATVTLLRPGAETSQAAQRLMSNSLSSPVISSVPLTSPSSLPSPLT 710
Fly 489 -----TPTSGSLLSP------------------ALGG---GSGTPNSAAQEFSFKAKQEVYVMQR 527
||.:|..||| :||. |..:..|:..:.:.:||.|.:|.||
Zfish 711 SAPVRTPNTGPSLSPVAQSKLTATNGTVGLKLSSLGQSSIGQNSQESSQDKQAEQAKLESHVHQR 775
Fly 528 ISELQREGLWTERRLPKLQEPSRPKAHWDYLLEEMVWLAADFAQERKWKKNAAKKCAKMVQKYFQ 592
|:||::||.|:..|||||||..|||:.||||||||.|:||||||||:||..||||..:...:|..
Zfish 776 IAELRKEGQWSASRLPKLQESCRPKSQWDYLLEEMQWMAADFAQERRWKMAAAKKLVRTCARYHV 840
Fly 593 DKATAAQRAEKAQELQLKRVASFIAREVKSFWSNVEKLVEYKHQTKIEEKRKQALDQHLSFIVDQ 657
:|....:|.:|.:|::|:.:||.|||.|..||||:|::||.||..:|.:|:|:.|....:....|
Zfish 841 EKKKMGEREKKEEEMRLRHIASTIARGVDYFWSNIEQIVEIKHHFEIYDKQKKVLCLQKASSKGQ 905
Fly 658 TEKFSQQLVEGMNKSVADTPSLNSSRLTSPKRESDDDFRPESGS------EDDEETIAKAE--ED 714
..|..| :....|.|.|.|.|: |..|.| ||:|.||.:.| |.
Zfish 906 CAKSGQ------------SSDKESKRETGPSRK-----RKSSTSLSDVEVEDEESTIEEQEATEA 953
Fly 715 AADVKEEVTALAKESEMDFDDFLNDLPPGYLENRDKLMKEEQSSAIKTETPDDSDDSEFEAKEAS 779
|||.|.|:..|.||:|:..||.:......|.|. .|.|..|..||
Zfish 954 AADQKAELAELTKEAEVPLDDLVKQYAGAYAEG--------------FEWPQPSSQSE------- 997
Fly 780 DDDENTISKQEEAEQEIDHKKEIDELEADNDLSVEQLLAKYKSEQPPSPKRRKLAPRDPELDSDD 844
|:| :|||| |::. .|||..
Zfish 998 DED------REEAE----------------DMNT-------------------------PLDSPH 1015
Fly 845 DSTAVDSTEESEDAATEDEEDLSTVKTDTDMEEQDEQEDGLKSLMADADATSGAAGSGSTAGASG 909
|:..:|| :...|...|| ..:|:|..|
Zfish 1016 DAVLIDS-------------------------------------LLSMDQYRGA--ERTTSGPDG 1041
Fly 910 NKDDMLNDAAALAESLQPKGNTLSSTNVVTPVPFLLKHSLREYQHIGLDWLVTMNERKLNGILAD 974
.....:.:.||..:.:.|||:..::....:..|.||..||||||.:|::||.:::.:.|||||||
Zfish 1042 KPTKDIAEVAAATDLILPKGSARTTLTSRSSPPSLLHGSLREYQQVGVEWLASLHRKNLNGILAD 1106
Fly 975 EMGLGKTIQTIALLAHLACAKGNWGPHLIVVPSSVMLNWEMEFKKWCPGFKILTYYGSQKERKLK 1039
|.|||||:||:|..|||||.:|.|||||:||.:..:||||||||:||||.|||.|.||:::|:.|
Zfish 1107 ETGLGKTVQTVAYFAHLACNQGIWGPHLVVVRTCKLLNWEMEFKRWCPGLKILLYLGSRRQRRYK 1171
Fly 1040 RVGWTKPNAFHVCITSYKLVVQDQQSFRRKKWKYLILDEAQNIKNFKSQRWQLLLNFSTERRLLL 1104
|..|.:||.||||:|||||:::||..|.|::||:|:|||.|.|||...:.|:.:.|..:::|:||
Zfish 1172 RSRWCEPNNFHVCVTSYKLLLKDQSHFLRRRWKHLVLDEVQLIKNMTEKHWETIFNIKSQQRILL 1236
Fly 1105 TGTPLQNDLMELWSLMHFLMPYVFSSHREFKEWFSNPMTGMIEGNMEYNETLITRLHKVIRPFLL 1169
..|||||.|.|||:::|||:|.:...:..| |:....:.|.:|...|:.|||::|:||:|
Zfish 1237 INTPLQNTLKELWTMIHFLLPGITHPYLNF------PIKPGTDQNQDYCHKLVIRLHRMIQPFIL 1295
Fly 1170 RRLKKEVEKQMPKKYEHVITCRLSNRQRYLYEDFMSRAKTRETLQTGNLLSVINVLMQLRKVCNH 1234
||.|::|||||||||||::.||||.||:.:|||.:.:...:|.|:||:.:.|:.|||||:|:|||
Zfish 1296 RRSKRDVEKQMPKKYEHILKCRLSKRQKSMYEDILIQPSAQEALKTGHFVRVLEVLMQLQKICNH 1360
Fly 1235 PNMFEARPTISPFQMDGITFHTPRLVCDIMEYDPFTQINLETLNLLLLHLEQTMTAYVSH----K 1295
|::.:.|.|.:.:....:.::||.|:.:.::.|.:..::|...: |::.|..:|.|.:. |
Zfish 1361 PDLIQPRDTHNSYVCQPLQYNTPSLLLNALQQDQWKTVDLSLFD--LINNEGKLTRYEAEEALPK 1423
Fly 1296 SRLLAPPRKLIEDIDTAPLPAPRCPNGKYRFHIRVRSAELAQRIKLNAVKVGASPAMRLEGSKIM 1360
.|: .::|||:|..| ..|..|....||.
Zfish 1424 IRM---TKQLIEEIYNA-----------------------------------RDPPARPRPCKIK 1450
Fly 1361 PMRNLL-------PSGRVLKRVSASINPVNMALKPVVINSVVTTTSSSTTA-------------S 1405
|||..| |.||::...|:: ..|.:...:.:..|||::|.|| :
Zfish 1451 PMRLFLPVQYGTKPEGRLVPMTSST----TQAPRTTTVTTAPTTTTNSVTAVSNTQPRGKSPLTT 1511
Fly 1406 SPTGALSVLSNSK---LLGARSQINAPTPAKVAKTMQDGKPFFYLTPATNSGA----------AG 1457
:|:...|:::.|. |.|| .|.|..:..:| |.|.....||....| ..
Zfish 1512 TPSAQASIINCSSGPLLTGA-----IPNPPSIPLSM--GVPGVTTMPAVTPQAPSPVPLQPSLVS 1569
Fly 1458 ARLTLTSKTTASAST-------------------------------TTSRTTVTASTTS------ 1485
.||.|:|:..|...: |.|::.:...||.
Zfish 1570 QRLVLSSQAQARLPSGDVVKVAQLVGQSRIAQPETPVTLQFQGNKFTLSQSQLRQLTTGQPLQLQ 1634
Fly 1486 -------------GQQLIR---DPIVKDLATHV-------------------KSTVQKQSIANGK 1515
||.|:| .|:|....... .:|:...::....
Zfish 1635 GTLGNILQIVSAPGQPLLRPQGPPMVMPTVPQAVPAQNSSGTPPPATSTPPQANTMASTTVTPAN 1699
Fly 1516 TEPEEETEAEDPYKVQELIQMRKEQRLAALKRMAMINRRRTDATPIYGED----CREAIQRCMQA 1576
|:.|...:..:....||..:.|..|....|..:...|.||:..:.:||.| |.....|...|
Zfish 1700 TDMETNAKHSNNSTSQESSEERNRQLKERLSSLFHANERRSSRSVLYGSDLVKTCSVYEGRPPPA 1764
Fly 1577 TRSLKRSTWQ-------TRGYANCCTAMAHRNGWSLNHLLKSFEERCADLKPVFANFVIYVPSVC 1634
..:.:.|.|. .|....|.:.:| ||...:.|..|:.|....:...|...:|:..
Zfish 1765 FPAPQHSRWSWVGRDSCIRAQQTCVSTVA-----SLRSAILSNTEQEAAASTLLKRFSWILPAAV 1824
Fly 1635 APRIRRYVQNLSSTHWQHEQRIENIVDQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKLQTMD 1699
||..:.|..|...::...::.....:.:|..|..|.:..:.......|||..:::.|.|||:.:.
Zfish 1825 APPPQLYACNPPPSYSLAQKSFRRQLQEASAPFNAEIRKLACPPVASFPDAHMLEMDSGKLEALS 1889
Fly 1700 RLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHGHIYLRLDGSTRVEQRQILMERFNGDKRIFCF 1764
.||::|.....||||||||..|||:||:||::....|:|||.|..:|:||..::::|.:::|||.
Zfish 1890 ILLQKLSAENRRVLIFTQMASMLDILESFLDHRHLTYVRLDESLSLEERQEQVKKYNRNRQIFCT 1954
Fly 1765 ILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSERTIEVNILKK 1829
||:.|......::..|||::|||:|.||:||.:.|:.|.:||:::|:|||||.|..:||..:||.
Zfish 1955 ILTNRCCSAMGHVFDADTIVFYDTDLNPSMDMRTQEWCDKIGRSKDIHIYRLESGNSIEEKLLKN 2019
Fly 1830 ANQKRMLSDMAIEGGNFTTTYFKSSTIKDLFTMEQSEQDESS------QEKSENKDRIVATTTLS 1888
.. |.::.::|.:|.::|..:....||:|||.:|....::.. ||.|.::
Zfish 2020 GT-KDLIREVAAQGMDYTLAFLTQRTIQDLFEVEAGSGEKVEEFVVLHQEPSPSE---------- 2073
Fly 1889 DTPSTVVETEKQSLRAFEHALAAAEDEQDVQATKTAKA--EVAADLAEFDENIPIATEDPNAEGG 1951
..|..|.....|:|..........|:|..|:..:..|: |.|....|.| .|.|
Zfish 2074 SIPPHVARPYIQALNTIRQETQYEEEEGQVEVDEDVKSDKEKAGGPVEMD-----------IEEG 2127
Fly 1952 PQVELSKADLEMQNLVKQLSPIERYAMRFVEETGAAWTAEQLRAAEAELEAQKREWE--ANRLAA 2014
.:.|.|:.: |:..:::||:||||||:.::| ....:|..:..:..:|..||.|| ..:...
Zfish 2128 AREETSQLE-ELAAVMEQLTPIERYALHYLE---YLHISEDEQVVKERMETTKRGWELQLQQKLK 2188
Fly 2015 MHKEEELLKQETEAEEMLTYSRKDSSNQVWISRN---TMEQMPMWCPPTPPQDNDNDIYIDYSLS 2076
:.|||::: ||.| |::|:|:|:|:.|..::..| ..|.||:|.||||||| |||||||..:.
Zfish 2189 VEKEEQMI-QEDE-EDLLSYTREDAYNMEYVFENEDGQTEIMPLWTPPTPPQD-DNDIYIDSVIC 2250
Fly 2077 FMYELEPIAETDLPPVYVRKEHKRSRTDAGYDGSRRPNKMRREDNYVPPRSLFDRPTPQLARLRR 2141
.||:..|:.|:.|||||||||.||....:... |..|....::.:|||||||:.: |.::||
Zfish 2251 LMYDTAPMPESKLPPVYVRKERKRHMDPSALG---RKKKKGHGESVIPPRSLFDKAS--LLKVRR 2310
Fly 2142 ELKSQRFRGSFKPNMPIPGLKPQLPTKPLTEPEAMAEWCVFEDMAILHVLVNLQGLPCSLMLLSP 2206
::|.|:...|.|...|.....|.|....:...:...||.:.||.|:|..:..|..||.:|.::||
Zfish 2311 DVKDQKKNFSLKQQAPFAKPLPSLLKPAMESGQDNPEWLISEDWALLQAVKQLLELPLNLTIVSP 2375
Fly 2207 GQTPNWDLVSEMVNFCSKTYRSARQCRWRYETHIQPREEGKVV--ESPKKQKKLKPTLRTEYLKS 2269
..||||||||::||.||:.|||.:|||:|||..|.||||||:: .:|||.| .::.|...
Zfish 2376 AHTPNWDLVSDVVNSCSRIYRSPKQCRYRYENVIIPREEGKLIYDANPKKNK-----TKSIYKSK 2435
Fly 2270 PLRYLRTTQLYVSDNNASFYKTMRSRFDSIKTAYLKKAPPPKRQFSA-PSLMNPKHMEVLQEFGI 2333
..|.|||.|:|..|:||:..:...:||:.:|....|::||.|..... |...||||..||.|.||
Zfish 2436 NSRPLRTCQIYTQDDNATQIQLYSNRFELMKIIASKRSPPIKPLLGMNPFQKNPKHASVLAESGI 2500
Fly 2334 LNYDQPVSPQNIAAMKANKIREKQRGQQMSQPPVGVGVVQQMQQQSQQQQQPAPPPLPQQQQPQQ 2398
:||:|:.|..:|:.:|.:| .|::.|.:::. |:.||.:|||||.. ...|||.
Zfish 2501 -SYDKPLPPIQVASQRAERI-AKEKKQALAEQ-------QRAQQLAQQQQQTT-----GAAQPQG 2551
Fly 2399 VVQQVQQQQQQQQQQQQQQVVQQQLPTVSNVQQTLPVQQTVELVQQQPTTTTTVAVPAAGGQLQQ 2463
...|.|.|.| .||||.|
Zfish 2552 AAAQPQAQTQ---------------------------------------------TPAAGAQ--- 2568
Fly 2464 LQIQHLTSSNVSPGQQTAILLHQPQQQLRTHPGQGGQSNTQQLVKTIVGTSSSLTAGQLQQLAQQ 2528
:|..| ||.| ||....:||
Zfish 2569 --------ANAVP---------QPSQ-----PGAAAVANT------------------------- 2586
Fly 2529 SAVASGGQSSVSVVLTTPVQTLPSVVQPQIGSGAQIVSISSQTLPVNSSPQLGSIVQTQSLPQVV 2593
.|||..::|..: |:.:|
Zfish 2587 ------------AVLTGALKTAAA----------------------------GTSIQ-------- 2603
Fly 2594 SVSTLPTVGTVLTTTANQPQQQHQTTAVTTLNTTMLRGQRIVSTAAGNTLQQRTTAGGQSIVSMP 2658
|..||| .|..||:|.|
Zfish 2604 -----PAAGTV-------------------------SGNVIVNTVA------------------- 2619
Fly 2659 NLGQGASPSQFQTQLRLA------AVPTSPATQTTQLVTTKGIPVSALQQGGKTTVIPVTQQSGG 2717
|..|.|||...||| |:|.: .|.|.|:|.|:|
Zfish 2620 ----GVPPGQFQANKRLASPVIPGALPAT-GTATAQVVHTRG----------------------- 2656
Fly 2718 AHIQLYRQRSLKVLQTTTQAVPSGSAGATGATANLVQAGGTIIQASNMATHVTSQKV-AVSGMPG 2781
|||:.:|.| .:....|||.| ||
Zfish 2657 -------------------AVPAAAAPA------------------EVVAIATSQSVRAV----- 2679
Fly 2782 TSTTVQAGNVVSSVQMHGQARTQFIKQMAAGKQQLQRQVVSADGTTTTTAAGDMLLVKRHNILAA 2846
|.|.|..|||:....||::|:.:...|...|..|.:.:: ..||.::
Zfish 2680 --TPVTASAVVSTNLTSGQSQTRTLVATAPAVQLSQNKQIT-----------QQLLFRQ------ 2725
Fly 2847 QKAQQASGALFTTTTGQQQQQQQQQ-----GQLPVAGQPQ---------QVTQHQIASLVKASTA 2897
|:.|| ||||||||| .|:...|:|| |:.|.|:|:.|.|:..
Zfish 2726 QQLQQ-----------QQQQQQQQQPQATSPQIKAVGKPQQELLKQKKLQMAQQQVAAAVAAAQG 2779
Fly 2898 AAASGS----SVNAGGVTVSAT-NPTV------QAGSV--NMTLPQLKPGSQIKVTMPNQMRHLQ 2949
..|..: .|:| |.:|| ||.: :||:| ..|:..|:.....:|..|..::
Zfish 2780 QQAPSTQQPQQVHA---TPAATANPQIATVAAPRAGAVLAGTTVTNLQVARLTRVPAPGSIQ--- 2838
Fly 2950 MQQQLTMPRKISRMTQLVSASGQPTATNIITTTGPQQQQQGVTVSGGGTLP-TVASQQQQQQHQQ 3013
:..||| |...:|...|......|..||..||| |:|..........
Zfish 2839 ------------------AQPGQP-AQVTLTKPPPVVSVPAVVSSGVTTLPVTMAGISVAIGQAP 2884
Fly 3014 KVGGGNSVQAQLLHIQNTKGLSNSVTMQQIQQVMRSGQQGTLATTNLVLGKTSVGRVIPVSVASQ 3078
|.|| ..:::...:||:||::...:|..:|.. .:|...
Zfish 2885 KTGG--------------PMVTHPFQVQQVQQLLHRQKQQAVAQA--------------AAVQKA 2921
Fly 3079 ANQRQTIQVVSAASAQALAAGNLRTHVAGPSIASTLKVAAPGSAGGQTTQQTLIAALQHNQRQNA 3143
|..:||...|...:||..|....:.:...| ..|| ...|....::...|:..|
Zfish 2922 AQPQQTQAAVQQKAAQTPAQQQQKVYTTAP--------LQPG-----IKTQFFTTSITQPQKTAA 2973
Fly 3144 SPVRLQTTAGGNLLAVVQQQQQQQHTSIAGPTAGPAEVMTITQTTTTLPTVGSLQQQQQQQQQQG 3208
|| ::|.| .:..:|||| .::.|....|:..|:. .|...|..||:|.|.|.|....
Zfish 2974 SP-QIQVT---KIPQIVQQQ------IVSSPQQIQAQPQTVA-LTQAAPAAGSVQAQAQVQVIPA 3027
Fly 3209 GISQPTTQQVRKLVQKKIL 3227
|.:|...| ||:|::::
Zfish 3028 GTAQVVQQ---KLLQQQVV 3043
| 
