Protein Alignment dom and Marcal1

DIOPT Version :10

• Sequence 1: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Sequence 2: NP_608883.1
• Gene: Marcal1 / 33709
• FlyBaseID: FBgn0031655
• Length: 755
• Species: Drosophila melanogaster
• Alignment Length: 807
• Identity: 161/807 - (19%)
• Similarity: 280/807 - (34%)
• Gaps: 248/807 - (30%)

  Fly  1220 SVINVLMQLRKVCNHPNMFEARPTISPFQM--DGITFHTPRLVCDIMEYDPFTQI--NLETLNLL 1280
            |.:|.|..:::..|..   .:|....|:|.  .|...:.|.|.....:..|...:  |..|.||.
  Fly    92 SFLNALKAIKQTSNRE---LSRGAAHPYQRPNGGNERNKPTLSLSSDKEKPVAVLLGNSITCNLY 153

  Fly  1281 LLHLEQTMTAYVSHKSRLLAPPRKLIEDIDTAPLPAPRCPNGKYRF---------HIRVRSAELA 1336
            |:...:.......:..:|:.    :.:::.|      :|.:|:.|.         .::..:|:|.
  Fly   154 LISTHRFAAQTSGYHEQLVT----VFKNMPT------KCYDGQTRIWSFDLSDYQSLKTHAADLK 208

  Fly  1337 QRIKLNAV--KV----GASPAMRLEGSKIMPMRNLLPS------------------------GRV 1371
            ..:.:|.:  ||    |..|        ::|.|::|.|                        ||:
  Fly   209 PYVHMNGIPKKVLDLCGQPP--------VVPERSVLASIEPKLADQLMPFQQDGVCFAIAQKGRI 265

  Fly  1372 LKRVSASINPVNMALK---------PVVINSVVTTTSS------STTASSPTGALSVLSNSKLLG 1421
            :......:.....||.         |:::.:..:|..|      ......|...:.||:|::|..
  Fly   266 MICDEMGLGKTYQALAVADYFKDDWPLLVCTTASTRDSWAKHIMDLLPKVPIHYVQVLNNNQLYV 330

  Fly  1422 ARSQINAPTPAKVA----KTMQDGKPFFYLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTAS 1482
            ..:::...:...:.    |.||....|.....:.....:.|:.|    |||...|..::..|..|
  Fly   331 GEAKVLITSYNMMERHEDKLMQRKFGFIIFDESHTLKNSKAKCT----TTAKRLTDQAKRVVLLS 391

  Fly  1483 TT----------SGQQLIRDPIVKDLATHVKSTVQKQSI----ANGKTEPEEETEAEDPYKV-QE 1532
            .|          :..|:|....:..:....:....|||.    |||::..||       .|| ..
  Fly   392 GTPALSRPLELFTQLQMIDGKFMNFMEFTTRYCDGKQSTFGWDANGQSNLEE-------LKVILH 449

  Fly  1533 LIQMRKEQRLAALKRMAMINRRRTDATPIY---GEDCREAIQRCMQATRSLKRSTWQTRGYANCC 1594
            |..|.:..::..|.::|..||......|..   ..:.:|.:....:..::.|
  Fly   450 LKYMLRRTKVEVLPQLAEKNRETVVLDPALVWTNAETKETLDAFNKELKTAK------------- 501

  Fly  1595 TAMAHRNGWSLNHLLKSFEERCADLKPVFANFVIYVPSVCAPRIRRYVQNLSSTHWQHEQRIENI 1659
                   |.:...:|..|..|.|::|         ..:|||     |::.|..     ||:
  Fly   502 -------GRATEEILLRFYARTAEVK---------TRAVCA-----YLKTLVK-----EQK---- 536

  Fly  1660 VDQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKLQTMDRLLRQLKVNGHRVLIFTQMTKMLDV 1724
                                 ||                              :||.....|:|.
  Fly   537 ---------------------KF------------------------------IIFAHHRVMMDA 550

  Fly  1725 LEAFLNYHGHIYLRLDGSTRVEQRQILMERFNGDKRIFCFILSTRSGGVGINLTGADTVIFYDSD 1789
            :..||:.....|:|:||.||.:.|...::.|.........:||.::...||.||.|:.::|.:.|
  Fly   551 ISDFLSGLKVHYIRIDGQTRSDHRSDSVDTFQKKSSCKVALLSLKACNSGITLTAAEIIVFAELD 615

  Fly  1790 WNPTMDAQAQDRCHRIGQTRDVHIYRLVSERT---IEVNILKKANQKRMLSDMAIEGGNF----- 1846
            |||:..|||:.|.||||||:.|....|::..|   |..|:||  |::.:||.:.|...|.
  Fly   616 WNPSTLAQAESRAHRIGQTKPVICRYLIAHNTADDIIWNMLK--NKQEVLSKVGIFAENLQKATH 678

  Fly  1847 TTTYFKSSTIKDLFTMEQSEQDESSQEKSENKDRIVATTTLSDTPSTVVETEKQSLRAFEHALAA 1911
            |.....|..|::.|                           |.:.||.:|.|:.|::.:...:.|
  Fly   679 TAAPTSSHKIEEYF---------------------------SPSTSTSLEPERNSIKQYFSTIPA 716

  Fly  1912 ---AEDEQDVQATKTAKAEVAADLAEF 1935
               .|...:.:.||..|||  :|:|.|
  Fly   717 KEPPEQNNNTEMTKVNKAE--SDIAAF 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dom	NP_001286676.1	HSA	543..614	CDD:214727
		HepA	692..>1235	CDD:440319	4/14 (29%)
		DEXQc_SRCAP	949..1171	CDD:350761
		SF2_C_SNF	1685..1817	CDD:350180	37/131 (28%)
		DISARM_DrmD_b	<1702..>1936	CDD:468472	68/245 (28%)
		HEC1	<1858..>2031	CDD:444066	17/81 (21%)
		SP1-4_N	2486..>2819	CDD:425404
Marcal1	NP_608883.1	HARP	160..216	CDD:462166	8/65 (12%)
		HepA	<233..666	CDD:440319	110/539 (20%)
		DEXHc_HARP_SMARCAL1	247..456	CDD:350768	39/219 (18%)