Protein Alignment dom and Ino80

DIOPT Version :9

• Sequence 1: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Sequence 2: NP_001248333.1
• Gene: Ino80 / 296084
• RGDID: 1310969
• Length: 1559
• Species: Rattus norvegicus
• Alignment Length: 1563
• Identity: 413/1563 - (26%)
• Similarity: 658/1563 - (42%)
• Gaps: 429/1563 - (27%)

  Fly   429 PLLPCNTSAGSTALRRPQGQNNASSGSAAASGGGGSLTPTPLYTGNG---PAALGGSGGLTPGTP 490
            ||||   .:|...::..:...|:..|..:.:...|.|.|   |:.||   ..:....|.|...:.
  Rat    60 PLLP---ESGDPLIQVKEEPPNSLLGETSGASSSGLLNP---YSLNGVLQSESKSDKGNLYNFSK 118

  Fly   491 TSGS---LLSPALGGGSGTPNSAAQEFSFKAKQEVYVMQRISELQREGLWTERRLPKLQEPSRPK 552
            ...|   |.|..|...|...:|.::: :...::|:       .|.||.|....||.|.::..:.|
  Rat   119 LKKSRKWLKSILLSDESSEADSQSED-NDDEEEEL-------SLSREELHNMLRLHKYKKLHQNK 175

  Fly   553 AHWDYLLEEMVWLAA-------DFAQERKWKKNAAKKCAKMVQKYFQDKATAAQRAEKAQELQLK 610
            ...|..|::..:.:|       .|.::::......||      |:.:||...|    |.::::.|
  Rat   176 YSKDKELQQYQYYSAGLLSTCDPFYEQQRHLLGPKKK------KFKEDKKLKA----KLKKVKKK 230

  Fly   611 RVASFIAREVKSFWSNVEKLVEYKHQTKI------------EEKRKQALDQ--------HLSFIV 655
            |      |..:.| |:.|....:.||||:            .:|:..:::|        .||.:.
  Rat   231 R------RRDEEF-SSEESPRHHHHQTKVFAKFSHDAPPPGTKKKHLSIEQLNARRRKVWLSIVK 288

  Fly   656 DQTEKFSQQLVEGMNKSVADTPSLNSSRLTSPKRESDDDFRPESGSEDDEETIAKAEEDAADVKE 720
            .:..|.::|      ||.|....|.:||..:.:...:.........::.:||:.:|..
  Rat   289 KELPKANKQ------KSSARNLFLTNSRKLAHQCMKEVRRAALQAQKNCKETLPRARR------- 340

  Fly   721 EVTALAKESEMDFDDFLNDLPPGYLENRDKLMKEEQSSAIKTETPDDSDDSEFEAKEASDDDENT 785
                |.||..:            |.:..:|:.||.:..|            |.||.|....||
  Rat   341 ----LTKEMLL------------YWKKYEKVEKEHRKRA------------EKEALEQRKLDE-- 375

  Fly   786 ISKQEEAEQEIDHKKEIDELEADNDLSVEQLLAKYKSEQPPSPKRRKLAPRDPELDSDDDSTAVD 850
              :..||:::   :::::.|     ::..:|.|.:.|.     ||          |...|....:
  Rat   376 --EMREAKRQ---QRKLNFL-----ITQTELYAHFMSR-----KR----------DMGHDGIQEE 415

  Fly   851 STEESEDAATEDEEDL-STVKTDTDMEEQDEQEDGLKSL---------------MADADATSGAA 899
            ...:.||::|:.:.|: ..|..:...|:.|......::|               ..|.||....|
  Rat   416 ILRKLEDSSTQRQIDIGGGVVVNITQEDYDSNHFKAQALKNAENAYHIHQARTRSFDEDAKESRA 480

  Fly   900 GSGSTAGASGNKDDMLNDAAALAESLQPKGNTLSSTNVVTPVPFLLKHSLREYQHIGLDWLVTMN 964
            .:...|..||:.   ..::.:||......|..:       |.|.:....|:.||..|::||..:.
  Rat   481 AALRAADKSGSG---FGESYSLANPSIRAGEDI-------PQPTIFNGKLKGYQLKGMNWLANLY 535

  Fly   965 ERKLNGILADEMGLGKTIQTIALLAHLACAKGNWGPHLIVVPSSVMLNWEMEFKKWCPGFKILTY 1029
            |:.:|||||||||||||:|:||||||||..:..|||.||:.|:|.:.||..||.::.|.||:|.|
  Rat   536 EQGINGILADEMGLGKTVQSIALLAHLAERENIWGPFLIISPASTLNNWHQEFTRFVPKFKVLPY 600

  Fly  1030 YGSQKERKLKRVGW------TKPNAFHVCITSYKLVVQDQQSFRRKKWKYLILDEAQNIKNFKSQ 1088
            :|:..:||:.|..|      |:...|||.||||:|||||.:.|:|.||:|::|||||.:|:..|.
  Rat   601 WGNPHDRKVIRRFWSQKTLYTQDAPFHVVITSYQLVVQDVKYFQRVKWQYMVLDEAQALKSSSSV 665

  Fly  1089 RWQLLLNFSTERRLLLTGTPLQNDLMELWSLMHFLMPYVFSSHREFKEWFSNPMTGMIEGNMEYN 1153
            ||::||.|....||||||||:||.:.|||:|:||:||.:|.||.||.||||..:....|.....:
  Rat   666 RWKILLQFQCRNRLLLTGTPIQNTMAELWALLHFIMPTLFDSHEEFNEWFSKDIESHAENKSAID 730

  Fly  1154 ETLITRLHKVIRPFLLRRLKKEVEKQMPKKYEHVITCRLSNRQRYLYEDFMSRAKTRETLQT--- 1215
            |..::|||.:::||:|||:||:||.::..|.|.::.|:|::||:.||:...::....:.||:
  Rat   731 ENQLSRLHMILKPFMLRRIKKDVENELSDKIEILMYCQLTSRQKLLYQALKNKISIEDLLQSSMG 795

  Fly  1216 ------GNLLSVINVLMQLRKVCNHPNMFEARPTISPFQMDGITFHTPRLVCDIMEYDPFTQINL 1274
                  ....|::|::||.|||||||.:||.:.|.|||.:....:...:.:....:...|.....
  Rat   796 STQQAQNTTSSLMNLVMQFRKVCNHPELFERQETWSPFHISLKPYEISKFIYRHGQIRVFNHSRD 860

  Fly  1275 ETLNLLLL-----HLEQTMTAYVSHKSRLLAPPRKLIED---------IDTAPLPAPRCPNGKYR 1325
            ..|.:||.     :::|::    .|        ||.|.:         ||.:|
  Rat   861 RWLKVLLSPFAPDYIQQSL----FH--------RKGINEGSCFSFLRFIDVSP------------ 901

  Fly  1326 FHIRVRSAELAQRIKLNAVKVGASPAMRLEGS-KIMPMRNL-LPSGRVLKR----------VSAS 1378
                   ||:|..:....:....:..:.|:.| ::..:|:. .|.|...:|          |...
  Rat   902 -------AEMANLMLQGLLARWLALFLSLKASYRLHQLRSWGEPDGESHQRYLRNKDFLLGVDFP 959

  Fly  1379 INPVNMALKPVVINSVVTTTSSSTTASSPTGALSVLSNSKLLGARSQINAPTPAKVAKTMQDGKP 1443
            ::..|:...|::         .|...||...|:|..|:..:...||
  Rat   960 LSFPNLCSCPLL---------KSLVFSSHCKAVSGYSDQVVHQWRS------------------- 996

  Fly  1444 FFYLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTASTTSGQQLIRDPIVKDLATHVK----- 1503
                  ||:|    .|..|.::..:.....:.|.|...         .|....|.:...:
  Rat   997 ------ATSS----LRCCLLTELPSFLCVASPRVTAVP---------LDSYCNDRSAEYERGVLK 1042

  Fly  1504 ---STVQKQSIANGKTEPEEETEAEDPYKVQELIQMRKEQRLAALKRMAMINRRRTDATPIYGED 1565
               |...||.:.||  .||..|:                          .:|||    :..:.|.
  Rat  1043 EGGSLAAKQCLLNG--APELATD--------------------------WLNRR----SQFFPEP 1075

  Fly  1566 CREAIQRCMQATRSLKRSTWQTRGYANCCTAMAHRNGWSLNHLLKSFEERCADLKPVFANFVIYV 1630
                                     |....::..:||||                     |:
  Rat  1076 -------------------------AGGLLSIRPQNGWS---------------------FI--- 1091

  Fly  1631 PSVCAPRIRRYVQNLSSTHWQHEQRIENIVDQALRPKLALLHPIISEMTTKFPDPRLIQYDCGKL 1695
                                                              :.|....:..|.|||
  Rat  1092 --------------------------------------------------RIPGKESLITDSGKL 1106

  Fly  1696 QTMDRLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHGHIYLRLDGSTRVEQRQILMERFNGDKR 1760
            ..:|.||.:||..||||||::|||:|:|:||.::.|..|.|:|||||:::.:|:.::..|.....
  Rat  1107 YALDILLTRLKSQGHRVLIYSQMTRMIDLLEEYMVYRKHTYMRLDGSSKISERRDMVADFQTRND 1171

  Fly  1761 IFCFILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSERTIEVN 1825
            ||.|:||||:||:|||||.||||||||||||||:|.||.||.||:|||:.|.:|||:.:.|||..
  Rat  1172 IFVFLLSTRAGGLGINLTAADTVIFYDSDWNPTVDQQAMDRAHRLGQTKQVTVYRLICKGTIEER 1236

  Fly  1826 ILKKANQKRMLSDMAIEGGNFTTTYFKSSTIKDLF-------------TMEQSEQDESSQEKSEN 1877
            ||::|.:|..:..|.|.||||.....|...:..|.             ..|:.:|:||::.|...
  Rat  1237 ILQRAKEKSEIQRMVISGGNFKPDTLKPKEVVSLLLDDEELEKKLRLRQEEKRQQEESNRVKERK 1301

  Fly  1878 KDR 1880
            :.|
  Rat  1302 RKR 1304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dom	NP_001286676.1	HSA	543..614	CDD:214727	15/77 (19%)
		ASF1_hist_chap	<674..831	CDD:304562	28/156 (18%)
		FAM176	<824..>868	CDD:291517	8/44 (18%)
		SNF2_N	952..1238	CDD:278600	141/300 (47%)
		DEXDc	969..1108	CDD:238005	79/144 (55%)
		Helicase_C	1692..1806	CDD:278689	66/113 (58%)
Ino80	NP_001248333.1	DBINO	275..404	CDD:404732	33/186 (18%)
		HepA	350..868	CDD:223627	191/566 (34%)
		DEXQc_INO80	520..748	CDD:350760	115/227 (51%)
		SF2_C_SNF	1093..1228	CDD:350180	74/134 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D188211at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920