Protein Alignment dom and rrp2

DIOPT Version :10

• Sequence 1: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Sequence 2: NP_596602.1
• Gene: rrp2 / 2540464
• PomBaseID: SPBC23E6.02
• Length: 1040
• Species: Schizosaccharomyces pombe
• Alignment Length: 1357
• Identity: 257/1357 - (18%)
• Similarity: 431/1357 - (31%)
• Gaps: 520/1357 - (38%)

  Fly   643 RKQALDQHLSFIVDQTEKFSQ-----QLVEGM----NKSVADTPSLNSSRLTSPKRESDDD---- 694
            |||||..  :|:.|.:...:.     :.|.|:    |..:|..|  |..:|.|.....::|
pombe    64 RKQALFN--AFMHDSSSSLNTMESNIEKVNGLFPNDNSVIALKP--NEEKLNSSLSVENNDSTYT 124

  Fly   695 ----FRPESGSEDDEETIAKAEEDAADVKEEVTALAKESEMDFDDFLNDLPPGYLENRDKLMKEE 755
                ..|:.|.:.........:.|...::.|:::                      :.||| ...
pombe   125 DATLIAPKIGLDRPNINAITIDVDGHSLQNEISS----------------------STDKL-SPS 166

  Fly   756 QSSAIKTETPDD---SDDSEFEAKEASDDDENTISKQEEAEQEIDHKKEIDELEADNDLSVEQLL 817
            ||.|:..:..|.   :|::.....::..||.|..:|....:.:..:.||...||          |
pombe   167 QSDALFEQKQDSLFWNDNAVIVVSDSESDDNNVRTKSSLNDHDKVNMKEKRNLE----------L 221

  Fly   818 AKYKSEQPPSPKRRKL-APRDPELDS-----------------------------DDDSTAVDST 852
            |...|      ||:|| .|..|.|.:                             :||.......
pombe   222 AFMNS------KRKKLELPSLPVLSTAGPSYTNSLALPPFHHHNNYKMFNTTHTLEDDKFLQGKG 280

  Fly   853 EESEDAATEDEEDLS------------------------------------------------TV 869
            ..:...:..||||..                                                .:
pombe   281 TSNNPISLSDEEDNEINFQNKRYGSDSVILPGGLLHDSKLPEPGKHLFHLQWYHDRFHNIEGFNL 345

  Fly   870 KTDTDMEEQDEQEDGLKSLMADADATSGAAGSGSTAGASGNKDDMLNDAAALAESLQPKGNTLSS 934
            ....:.:.||:|:..|:.|..|.|                  :.::||.            |:..
pombe   346 SDSNNQKVQDDQQQQLEELFKDLD------------------EQLVNDP------------TIRE 380

  Fly   935 TNVVTPVPFLLKHSLREYQHIGLDWLVTMNE-RKLNGILADEMGLGKTIQTIALLAHLACAKGNW 998
            ......:|.|::|     |..||.||..:.| .|..|||||:||||||:|.:|||........:.
pombe   381 GTPAGLIPTLMEH-----QKEGLMWLKRLEESSKKGGILADDMGLGKTVQALALLVTRPPESKSV 440

  Fly   999 GPHLIVVPSSVMLNWEME-FKKWCPGFK--ILTYYGSQKERKLKRVGWTKPNAFHVCITSYKLV- 1059
            ...||:.|.|::..|..| ..|..|..:  :..::||.|:.|:..    :..::.:.:|:|.::
pombe   441 KTTLIITPVSLLQQWHNEILTKIAPSHRPTVYIHHGSSKKHKIAE----QLMSYDIVLTTYNVIA 501

  Fly  1060 ------------VQDQQSFRR--------KKWKYLILDEAQNIKNFKSQRWQLLLNFSTERRLLL 1104
                        ::|....::        .:|..:||||||.|||..:...:......:..|..|
pombe   502 YEFKNKMAYDKSIEDNAPIKKFEHLPFFEAEWYRVILDEAQTIKNRNTLAARGCCLLESTYRWCL 566

  Fly  1105 TGTPLQNDLMELWSLMHFLMPYVFSSHREFKEWFSNPMTGMIEGNMEYNETLITRLHKVIRPFLL 1169
            :|||:||.:.|.:||:.||....:|....|.:.|:.|::..|.     ....:.|...:::..||
pombe   567 SGTPMQNGVEEFYSLIKFLRIKPYSDWSSFSKDFTIPLSSNIN-----TSAPMKRFRGLLKAVLL 626

  Fly  1170 RRLKK-EVEKQ----MPKKYEHVITCRLSNRQRYLYEDFMSRA--KTRETLQTGNLL----SVIN 1223
            ||.|. :::.:    :|.|........||:.:...|....|.|  :.|:.||.|.:.    |::.
pombe   627 RRTKNTKIDGKPILTLPPKTAVKSETDLSSSEMEFYNTLQSGAQIQMRKYLQEGTITTHYGSLLV 691

  Fly  1224 VLMQLRKVCNHPNMFEARPTISPFQMDGITFHTPRLVCDIMEYDPFTQINLETLNLLLLHLEQTM 1288
            :|::||:.|.||.:..||...                  :.:.|.|...|....|.:
pombe   692 LLLRLRQACCHPWLIVAREAA------------------VDDNDSFQAKNRAIYNQI-------- 730

  Fly  1289 TAYVSHKSRLLAPPRKLIEDIDTAPLPAPRCPNGKYRFHIRVRSAELAQRIKLNAVKVGASPAMR 1353
              |....:||     ||||.:        :|                             |..|.
pombe   731 --YPEAVNRL-----KLIETL--------QC-----------------------------SLCMD 751

  Fly  1354 LEGSKIMPMRNLLPSGRVLKRVSASINPVNMALKPVVINSVVTTTSSSTTASSPTGAL--SVLSN 1416
            :....::    ::|.|..|.|         ..|..|:.:|......:|....||..::  ..:..
pombe   752 VVAELLI----IVPCGHFLCR---------ECLTHVITSSEDMAKQTSNENISPKCSVCEEYIDT 803

  Fly  1417 SKLLGARSQINAPTPAKVAKTMQDGKPFFYLTPATNSGAAGARLTLTSKTTASASTTTSRTTVTA 1481
            .:||.                        |......||.|
pombe   804 ERLLS------------------------YALFRRYSGMA------------------------- 819

  Fly  1482 STTSGQQLIRDPIVKDLATHVKSTVQKQSIANGKTEPEEETEAEDPYKVQELIQMRKEQRLAALK 1546
                       |||                           :|::..:.:.:.::..:|
pombe   820 -----------PIV---------------------------DADNKLRTENISELLPKQ------ 840

  Fly  1547 RMAMINRRRTDATPIYGEDCREAIQRCMQATRSLKRSTWQTRGYANCCTAMAHRNGWSLNHLLKS 1611
                                                       |:|.
pombe   841 -------------------------------------------YSNI------------------ 844

  Fly  1612 FEERCADLKPVFANFVIYVPSVCAPRIRRYVQNLSSTHWQHEQRIENIVDQALRPKLALLHPIIS 1676
            .|.|...:| :|.:          |:           ||....:||..::            .:.
pombe   845 LENRQMGMK-IFTD----------PK-----------HWTTSTKIEKALN------------AVK 875

  Fly  1677 EMTTKFPDPRLIQYDCGKLQTMDRLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHGHIYLRLDG 1741
            |:..|.|.                         .::|||:|....|::........|..||...|
pombe   876 EIIKKQPT-------------------------DKILIFSQFVSFLELFTVPFRQEGIKYLMYTG 915

  Fly  1742 STRVEQRQILMERFNGDKRIFCFILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQAQDRCHRIG 1806
            .....:|...:..|..|..:...::|.::|.||:|||.|:.||..|..|||.::.||.||.||||
pombe   916 GLSTAERNQALINFEVDPNVRVLLISLKAGNVGLNLTCANHVIILDPFWNPYIEEQAVDRAHRIG 980

  Fly  1807 QTRDVHIYRLVSERTIEVNILKKANQKRMLSDMAI-EGGNFTTTYFKSSTIKDLFTM 1862
            |.:.|:|.|:|:..|||..:|...::||.|.|.|: |.|....:...:..:..||.|
pombe   981 QDKPVNILRIVTNNTIEERVLALQDRKRELIDSALGEKGLREISRLNTKELSFLFGM 1037

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dom	NP_001286676.1	HSA	543..614	CDD:214727
		HepA	692..>1235	CDD:440319	136/667 (20%)
		DEXQc_SRCAP	949..1171	CDD:350761	67/246 (27%)
		SF2_C_SNF	1685..1817	CDD:350180	38/131 (29%)
		DISARM_DrmD_b	<1702..>1936	CDD:468472	53/162 (33%)
		HEC1	<1858..>2031	CDD:444066	3/5 (60%)
		SP1-4_N	2486..>2819	CDD:425404
rrp2	NP_596602.1	HepA	<380..1016	CDD:440319	190/945 (20%)
		RING_Ubox	742..812	CDD:473075	17/143 (12%)