Protein Alignment dom and rad-54.L2

DIOPT Version :10

• Sequence 1: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Sequence 2: NP_501545.1
• Gene: rad-54.L2 / 177706
• WormBaseID: WBGene00007761
• Length: 1274
• Species: Caenorhabditis elegans
• Alignment Length: 1635
• Identity: 305/1635 - (18%)
• Similarity: 526/1635 - (32%)
• Gaps: 673/1635 - (41%)

  Fly   702 EDDEETIAKAEEDAADVKEEVTALAKESEMDFDDFLNDLPPGYLENRDKLMKEEQSSAIKTE-TP 765
            |.||.|:.:.:|:  :.::|:....::.:....:.||...|   ....|.:|.:.   |||: ..
 Worm     4 EIDENTMKEEQEE--EERDEIEEKEEKPDAQQQELLNIRIP---TQTKKSLKRKH---IKTDFGA 60

  Fly   766 DDSDDSEFEAKEASDDDENTISKQEEAEQEIDHKKEID-------------ELEADND------- 810
            :|.|::..||:..   ::..:.:.|:.:.|.||.::::             :|:..:|
 Worm    61 EDLDENVLEAQRL---EKQRLERLEKIKPENDHIQQMESLFLAGASEGQLPQLDLQDDDFEEMFG 122

  Fly   811 LSVEQLLAKYK---SEQP--------PSPKRRKLAPRDPEL-DSDDDSTAVDS------------ 851
            .|||....||:   .|:|        ||..|..:...|..| |||||....|.
 Worm   123 FSVENDNKKYRYGDEEKPEPMFHLQEPSTSRGHVDVVDLTLDDSDDDCLITDVKSVMPQVVPGRR 187

  Fly   852 ---TEESEDAATEDEEDLSTVKTDTDMEEQDEQEDGLKSLMADADATSGAAGSGSTAGASGN--K 911
               .:..:|....|:.|:          :.:.:...||.:.:..|..|.....|.....:|:  :
 Worm   188 MRWAQAEKDRIDADQMDI----------QHNIEARRLKKMRSAKDLESTEKKEGRLLVNAGHPEE 242

  Fly   912 DDMLNDAAALAESLQPK---GNTLSSTNVVTPVPFLLKHSLREYQHIGLDWLVTMNERKLNG--- 970
            |..:...:.|...|||.   |......|.:        .||.||             :|.:|
 Worm   243 DPDIFVISHLTHVLQPHQLGGIRFMYDNTI--------ESLGEY-------------KKSDGFGC 286

  Fly   971 ILADEMGLGKTIQTIALL-AHLACAKGNWGPHLIVVPSSVMLNWEMEFKKWCPG----------- 1023
            |||..||||||||.|... ..|...|..  ..|::||.:.:.||..|:.||.|.
 Worm   287 ILAHSMGLGKTIQVITFSEIFLRATKAK--KVLVIVPINTIQNWYSEYDKWIPKFSDTGDRIRSF 349

  Fly  1024 -----------------------------------FKILTYYGSQKERKLKR---------VGWT 1044
                                               |::|......|::|..|         .|::
 Worm   350 EVFLLGDGVKTFDQRVNLIEQWDQTGGVMLVGYDMFRLLIKMTLPKKQKKGRPKLNLSGISSGFS 414

  Fly  1045 KPNA-----------FHVCITSYKLVVQDQQSFRRKKW-----KYLILDEAQNIKNFKSQRWQLL 1093
            |.::           |....||...|.|:..|..|...     ..::.||...|||..::....|
 Worm   415 KDSSEDQKLRDEELEFETGFTSGGRVRQEAYSLIRSALLEPGPDLVVCDEGHKIKNITAEISMTL 479

  Fly  1094 LNFSTERRLLLTGTPLQNDLMELWSLMHFLMPYVFSSHREFKEWFSNPMTG--MIEGNMEYNETL 1156
            ...:|:||::|||.||||:|:|.:.::.|:.|....:.:.|.:.|..|:..  .::.:.:..:..
 Worm   480 GAINTKRRIVLTGYPLQNNLLEYFCMIDFVRPKYLGTRKSFIDRFEKPIKNGQCVDSSPDDVKIA 544

  Fly  1157 ITRLH---KVIRPFLLRRLKKEVEKQMPKKYEHVITCRLSNRQRYLYEDFMSRAKTRETLQTGNL 1218
            :.|.|   ::::.|:.||....::|.:|:..|:|:..|.|..||.||.:|:..||..   ...|.
 Worm   545 LQRTHVLVELVKGFVQRRTHHLLKKILPESKEYVLLLRKSQIQRQLYRNFVLWAKNE---IAANN 606

  Fly  1219 LSVINVLMQL---RKVCNHPNMFEARPTISPFQMDGITFHTPRLVCDIMEYDPFTQINLETLNLL 1280
            .:|.|.||..   .|:.|||                          ||:
 Worm   607 DAVFNPLMAFSACSKIWNHP--------------------------DIL---------------- 629

  Fly  1281 LLHLEQTMTAYVSHKSRLLAPPRKLIEDIDTAPLPAPRCPNGKYRFHIRVRSAELAQRIKLNAVK 1345
                           .||:...::..||              |.|.. :::.|:|.|:.:
 Worm   630 ---------------YRLVEQKKRAEED--------------KKRVE-QMKFAQLQQQQQ----- 659

  Fly  1346 VGASPAMRLEGSKIMPMRNLLPSGRVLKRVSASINPVNMALKPVVINSVVTTTSSSTTASSPTGA 1410
               ....:|:|..:|....::|
 Worm   660 ---QQQQQLQGMMMMGNNGMMP------------------------------------------- 678

  Fly  1411 LSVLSNSKLLGARSQINAPTPAKVAKTMQDGK--PFFYLTPATNSGAAGARLTLTSKTTASASTT 1473
                      |..:|.:   |.:....||:|.  |..|..|:..:                 |..
 Worm   679 ----------GFGAQFH---PQQNGMMMQNGSWHPNNYQMPSPFN-----------------SIP 713

  Fly  1474 TSRTTVTASTTSGQQLIRDPIVKDLATHVKSTVQKQSIANGKTEPEEETEAEDPYKVQELIQMRK 1538
            ::.:|.|:|:||                 ||..:.:.....|..|:.:.|.|         ::.|
 Worm   714 SNPSTPTSSSTS-----------------KSAKKTKKPRGSKKAPKSDEEDE---------EVEK 752

  Fly  1539 EQRLAALKRMAMINRRRTDATPIYGEDCREAIQRCMQATRSLKRSTWQTRGYANCCTAMAHRNGW 1603
            |.|:                                                         :..|
 Worm   753 ESRM---------------------------------------------------------KYDW 760

  Fly  1604 SLNHLLKSFEERCADLKPVFANFVIYVPSVCAPRIRRYVQNLSSTHWQHEQRIENIVDQALRPKL 1668
            :. .|.:.::|..                                       :||      ..|:
 Worm   761 TF-ELFEKYQEGV---------------------------------------LEN------GYKI 779

  Fly  1669 ALLHPIISEMTTKFPDPRLIQYDCGKLQTMDRLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYH- 1732
            .:...|:.|.|                        |:   |.::|||:|....||:||..|...
 Worm   780 VISLEILDEST------------------------QI---GEKILIFSQNLTALDMLEEILKKRQ 817

  Fly  1733 -------------GHIYLRLDGSTRVEQRQILMERFNGDKRIFCFILSTRSGGVGINLTGADTVI 1784
                         ...||||||:|....|:.|:.|||.:..:..|::|||:|.:||||..|:..|
 Worm   818 IRGKDGPGQRWEKNRNYLRLDGTTSGADREKLINRFNSEPGLSLFLISTRAGSLGINLVSANRCI 882

  Fly  1785 FYDSDWNPTMDAQAQDRCHRIGQTRDVHIYRLVSERTIEVNIL-----KKANQKRMLSDMAIEGG 1844
            ..|:.|||..||||..|.:|.||.:...:|||:.:.::|.:|.     |...|:|::.|..::
 Worm   883 IIDACWNPCHDAQAVCRVYRYGQQKKTFVYRLIMDNSMERSIFNRQISKHGLQQRVVDDAQVD-- 945

  Fly  1845 NFTTTYFKSSTIKDLFTMEQSEQDESSQEKSENKDRIVATTTLSDTPSTVVETEKQSLRAFEHAL 1909
                                                           :.:.:.|.::|..::.|
 Worm   946 -----------------------------------------------ANISQKELETLLMYDEA- 962

  Fly  1910 AAAEDEQDVQATKTAKAEVAADLAEFDENIPIATEDPNAEGGPQVELSKADLEMQNLVKQLSPIE 1974
                  |||...|.       :..::|...|:                     :.::.|::|  :
 Worm   963 ------QDVNHDKW-------NTDDWDFGDPV---------------------LDSITKRMS--Q 991

  Fly  1975 RYAMR-FVEETGAAWTAEQLRAAEAEL-EAQKREWEANRLAAMHKEEELLKQETEAEEMLTYSRK 2037
            .:|.: |:.||       .:..:|..| |.:|||           .:.|..:|...|.....|..
 Worm   992 MFAGKPFLHET-------LIMESEQSLSEQEKRE-----------AQLLFDRERRMENYDPLSGL 1038

  Fly  2038 DSSNQVWISRNTMEQMPMWCPPTPPQDNDNDIYIDYSLSFMYELEPIAETDLPPVYVRKEHKRSR 2102
            .|||  :.:......|.|..||..|..|:|   :..|.:..::
 Worm  1039 SSSN--FYNNAPGSSMGMMGPPPVPMFNNN---MQNSFNNHWQ---------------------- 1076

  Fly  2103 TDAGYDGSRRPNKMRREDNYVPPRSLFDRPTPQLARLRRELKSQRFRGSFKPNMPIPGLKPQLPT 2167
                    :.||::.......||:. |.:|.|.:::             |.|:.|    .||:|:
 Worm  1077 --------QSPNQLAPNFGSYPPQQ-FPQPMPNMSQ-------------FPPHGP----SPQIPS 1115

  Fly  2168 -KPLTEPEAM 2176
             :|...|..:
 Worm  1116 IRPSPMPHTL 1125

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dom	NP_001286676.1	HSA	543..614	CDD:214727
		HepA	692..>1235	CDD:440319	149/668 (22%)
		DEXQc_SRCAP	949..1171	CDD:350761	68/301 (23%)
		SF2_C_SNF	1685..1817	CDD:350180	48/145 (33%)
		DISARM_DrmD_b	<1702..>1936	CDD:468472	62/252 (25%)
		HEC1	<1858..>2031	CDD:444066	24/174 (14%)
		SP1-4_N	2486..>2819	CDD:425404
rad-54.L2	NP_501545.1	HepA	60..940	CDD:440319	239/1227 (19%)
		DEXHc_ARIP4	256..547	CDD:350827	71/313 (23%)